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25

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2014

Malaria No More News

Malaria No More NewsMother�™s First Fundraiser a Big HitOutbreak Responder: A different game for a different future.Q&A with Ray Chambers, Challenge #5: Fuel the FightThis Baby Accepts Credit CardsThe shrinking malaria mapBill Gates: We can eradicate malaria in our lifetimesChallenge #5: Fuel the FightChallenge 4: Data & MobileChallenge #4: Data & Mobile �“ Ashifi Gogo, CEO of SproxilChallenge 3: Block TransmissionChallenge #3: Block Transmission - Grey Frandsen, Kite PatchThis mosquito helps save lives from malariaChallenge #2: Complete Cure �“ Roger Waltzman, NovartisChallenge #2: Complete CureDeconstructing malaria with Femi KutiChallenge #1: Find the Parasite - Duncan Blair, AlereChallenge #1: Find the parasiteSolve For M: 5 Key Challenges to Ending MalariaDomenico�™s �œCiao” to malariaEating Pizza with Katharine McPheeFrom behind the scenes to the spotlightThe World�™s Deadliest Animal Gets AirtimeYoung Cameroonian comic joins the malaria fightIt�™s Summer Time, and the Life-Saving is EasyU.S. Senate Staff see malaria investments overseasHow Ebola Makes Malaria More DeadlyAsia: The next frontier in the malaria fightFrom malaria victim to malaria victor20,750 nets for pregnant women and children70,000 children treated through Venmo!

ntent-Type: text/xml; charset=utf-8 https://www.malarianomore.org/ en Copyright 2014 2014-11-20T22:38:00+00:00 https://www.malarianomore.org/news/entry/mothers-first-fundraiser-a-big-hit https://www.malarianomore.org/news/entry/mothers-first-fundraiser-a-big-hit

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

Being a mother of three children, Inge was touched by our Power of One campaign’s simplistic message – $1 given = 1 child saved – and decided to start her fundraiser. She learned about the campaign through her employer, Novartis, a company that has been committed to the fight against malaria for more than a decade.

Her boss at Novartis was the initial inspiration to get involved – and was one of her biggest supporters. “She was the first to donate a large amount of money to kick start the fundraiser,” said Inge. “And she also reached out to her personal network that resulted in donations adding up to several thousands of dollars.” Inge also shared stories with other co-workers who were also fundraising for the malaria fight.

Inge says the Power of One message made her first fundraising effort an easy one. “I just had to reach out to my family, friends and colleagues via email – and the results were amazing!” said Inge.

Inge’s campaign was so successful that she kept moving her fundraising goal up! “Two days after launching my fundraiser I had to increase the target,” said Inge. “One week before the end of the campaign, I was at 4400 treatments, so I raised the target again. I am proud that together, in the end we could raise more than 5600 treatments.”

While this was Inge’s first fundraising campaign ever, it doesn’t seem like it will be her last. “Personally it has been a very rewarding exercise,” said Inge. “I have been very blessed in many aspects and the campaign has given me the opportunity to ‘give back’ and feel the joy and pride in encouraging others doing the same.”

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Power of One, Supporter Spotlight, 2014--T:: https://www.malarianomore.org/news/entry/outbreak-responder-a-different-game-for-a-different-future https://www.malarianomore.org/news/entry/outbreak-responder-a-different-game-for-a-different-future

MNM is always looking for new and interesting ways to bring attention to the malaria fight. That’s why we’re really excited to partner with Global Gaming Initiative on its latest endeavor, which will benefit Malaria No More’s Power of One campaign.

When we started Global Gaming Initiative, (GGI) we wanted to utilize technology for good by creating a fun and easy way for people to make a difference. Our solution - mobile games. The goal being to inspire the developed world to get involved globally and provide the developing word greater access to education.  This year we ourselves received a massive education in the realities of global health issues, specifically malaria. The reality that malaria is a completely treatable disease, which an estimated 627,000 still die from annually, was both beyond unsettling and urgently motivating. We partnered with developers who share our desire to create a future without malaria to create our combative agent, Outbreak Responder, as we know that nothing is possible without health.

Outbreak Responder - using beautiful graphics and strategic challenges puts the player on a mission to cure communities from the spread of malaria. The best part is, being an Outbreak Responder player, you literally become an agent of change as your in-game contributions unlock malaria tests and treatments for African children through Malaria No More’s Power of One campaign. We have long admired the work Malaria No More does on the ground and are thrilled to partner with them to help you provide a healthy future for children with malaria. This is what fun and games and saving lives looks like. It’s the power of the change in your pocket – so download Outbreak Responder, put your game time to good use and help us create a better future, one child at a time.

Learn more about Outbreak Responder here.

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Mobile and Malaria, 2014--T:: https://www.malarianomore.org/news/entry/qa-with-ray-chambers-challenge-5-fuel-the-fight https://www.malarianomore.org/news/entry/qa-with-ray-chambers-challenge-5-fuel-the-fight

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge #5 focuses on a crucial component of finally ending malaria – maintaining and growing funding. For more, we spoke to Ray Chambers, co-founder of Malaria No More and United Nations Special Envoy for Financing the Health Millennium Development Goals and for Malaria.

1. What are some of the changes you anticipate in global financing for health over the next decade?

Funding has increased dramatically for global health since the world got serious about saving millions of children and mothers from preventable causes. The results have been impressive: Since 2000 the number of under-five deaths worldwide has declined from 12.7 million in 1990 to 6.3 million in 2013. But continuing to fund these gains from donor countries is not sustainable, especially if we want to move toward the elimination of malaria. We need to support three existing trends that can shift us to a new funding paradigm.

Endemic countries must increase their domestic health budgets. Domestic financing for malaria increased over the period of 2005 to 2012, from $436 million in 2005 to $522 million in 2012, rising at an estimated rate of 4% per year - a move in the right direction. But most countries still fall short of the Abuja target of dedicating 15% of their domestic budgets to improving health.

We must approach financing of life-saving commodities more creatively. We’re seeing early success from pay-for-performance social impact bonds that demonstrate the returns on investing in net distribution in Mozambique. An innovative tax on airline tickets to support work on AIDS, TB and Malaria has produced millions of dollars for AIDS treatment.

The private sector has recognized that healthier communities are better places to do business, and investing in the health of employees in the countries where they operate can help the bottom line as well.

2. How important have the Millennium Development Goals been to galvanizing support for malaria and other global health programs?

As a businessman I was drawn to the MDGs as time-bound, quantifiable targets against which we could measure our success. The inclusion of malaria in Goal 6 of the MDGs was essential to allowing the global health community to rally around the malaria targets. With this support came coordinated plans and, crucially, financing to enact those plans. Similarly with child and maternal health, by quantifying where we were, and where we needed to get, the MDGs provided the outline of a roadmap others could build upon and collectively enact. And with all 193 countries signing on to the MDGs back in 2000, their value has gone well beyond the tangible achievements of lives saved. They’ve linked all of us in a shared pursuit of something greater than our individual or even national selves. This shared global consciousness will carry the spirit and ambitions of the MDGs well beyond 2015.

3. How do you expect the funding landscape to change at the end of 2015, when the Millennium Development Goals deadline hits?

Relying on outdated models of north-to-south donor contributions will eventually hit a wall, and some would argue that the fatigue has already begun to set in. If we continue to think creatively about how we finance life-saving programs and commodities among a broader community - leveraging previously untapped resources, especially from the private sector - funding for health should continue to grow. Companies including Exxon Mobil, Chevron, Unilever and AngloGold Ashanti have demonstrated the leadership role businesses can play in keeping populations healthy. Similarly, the private sector plays an essential role in the research and development of new technologies and vaccines that could replace existing costly interventions. Now is the time to test new models of funding while investing in research that could deliver cheaper, more effective diagnostics, treatments, and vaccines.

4. What would the consequences be if malaria funding were scaled back?

Recent history has already demonstrated what happens when funding for malaria is decreased or held-up. From 2006 t0 2008 net coverage dropped due to delayed funding disbursements, resulting in an upsurge of malaria cases in 2009.  We’ve successfully covered almost every person in need of a net with a net, and in doing so saved over 3.3 million children since 2000. But as a result of this success, millions of children protected by nets have no immunity to malaria. If their nets aren’t replaced every three years, we will see malaria infections and deaths far exceed previous levels. Total funding for malaria control is expected to reach $2.85 billion each year between 2014 and 2016, substantially below the required amount for this period. We have come so close to lifting the burden of malaria off an entire continent. A final push - in political commitment, partner support and funding - will put the end of malaria deaths in our grasp and make elimination a reality.

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5 challenges to end malaria, Advocacy, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/this-baby-accepts-credit-cards https://www.malarianomore.org/news/entry/this-baby-accepts-credit-cards

Above:  Manishha Patel used inventive and fun memes to rally her friends to donate to Power of One.

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

MNM supporter Manishha raised money for our Power of One campaign with the help of her good-hearted loved ones and colleagues at her employer, the Genomics Institute of the Novartis Research Foundation (GNF). Fundraising for the cause came naturally to her given the lessons her parents taught her growing up – to be appreciative of the opportunities she has and to help those less fortunate.

“My parents are from a very rural and poor region of India,” says Manishha. “They always taught us to be grateful for the opportunities that were given to us in Canada and to help and care for the less fortunate.”

 



Manishha has always felt a strong urge to help those less fortunate. “I have always wanted to help people in underdeveloped countries, and Power of One affected me because of the impact it can have for people in Africa – the idea that just one dollar can save one person’s life really resonated with me and I wanted to help them in any way that I could.”

In addition to drawing on the wise words of her parents, she drew on the talents of her boyfriend. Together, they came up with eye-catching posters, featuring funny pictures of babies offering words of encouragement. And the kid theme didn’t end there – Manishha even inspired her niece and godchildren to donate their piggybank savings.

Manishha’s colleagues were a huge help too. They championed her cause to their families, friends, religious organizations, and sports teams, helping her break her past fundraising record of $500! “The sheer amount of support from GNF as a whole was phenomenal,” said Manisha. “The encouragement and support I received for the campaign was unbelievable, and helped me eventually recruit more than 330 friends to join Power of One.”

Good news is Manishha isn’t done yet. “This is the kind of work I have dreamed of doing and that is why I decided to get involved in the fundraiser,” said Manishha. “I will continue to promote the cause of Malaria No More and I hope that, in the very near future, malaria will no longer be as devastating a disease as it is now.”

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2014--T:: https://www.malarianomore.org/news/entry/shrinking-malaria-map-bill-gates https://www.malarianomore.org/news/entry/shrinking-malaria-map-bill-gates

This video of the shrinking malaria was shared by Bill Gates at the ASTMH conference.

Malaria has been killing for centuries. In 1900, it was taking lives from nearly every country on Earth, but the goal is to wipe this killer disease from the planet within a generation.

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2014--T:: https://www.malarianomore.org/news/entry/bill-gates-we-can-eradicate-malaria-in-our-lifetimes https://www.malarianomore.org/news/entry/bill-gates-we-can-eradicate-malaria-in-our-lifetimes

It was a packed house last night, as the best and brightest in the public health world poured into a New Orleans conference hall to hear one of the world’s most prolific philanthropists share his vision for the future of global health.

As Bill Gates joked, he was eager to finally have a captive audience for his thoughts on some of the world’s most pervasive diseases, as he typically bores dinner party guests with his excitement over discussing topics such as dengue fever, polio and malaria.

During his keynote speech at the Association of Tropical Medicine and Hygiene, Gates focused his remarks on Ebola and malaria. He spoke to the lessons the global health community can take from the Ebola crisis, and how it can serve to educate and strengthen our response to other public health issues. He spent the bulk of his speech talking about malaria, and urging the gathered group of the world’s premier scientists and doctors to embrace the idea of malaria eradication in our lifetimes. He also announced that the Bill & Melinda Gates Foundation will be increasing its already substantial financial commitment to fighting malaria by 30 percent.

Gates laid out the elements of a new strategy to achieve the ambitious goal of eradication, including fostering innovation in the surveillance and research & development arenas, as well as continued investment in malaria control efforts as we concurrently set our longer term vision on eradication.

You can read more on the new plan here. It is not an easy task, but with a shared vision and energy in the global health community, it is possible. His closing statement, which drew a standing ovation, echoed the sentiment that malaria eradication is within our grasp: “I’m optimistic we’ll get there faster than the skeptics think.”

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malaria elimination, 2014--T:: https://www.malarianomore.org/news/entry/challenge-5-fuel-the-fight https://www.malarianomore.org/news/entry/challenge-5-fuel-the-fight

To win the malaria fight, we need to rethink how we pay for it

Malaria No More was founded by two prominent business leaders, Ray Chambers and Peter Chernin, who saw combating malaria as a unique opportunity to save lives and improve livelihoods on a global scale. As Chernin put it, ending malaria represents “the best humanitarian investment in the world today.”

It’s easy to see why. Malaria is a devastating disease and one of the top killers of children under the age of five and pregnant women worldwide. It’s also a huge drain on economies, accounting for approximately $12 billion in lost economic productivity in Africa each year, due to the burden it places on health systems and the toll of work absenteeism and missed school days.

By contrast, the existing tools are simple and scalable - a mosquito net can protect a mother and child for three years for around $5; a 50 cent rapid diagnostic test and $1 treatment can save a child’s life – and, as this series highlights, revolutionary new technologies are just around the corner.

When Malaria No More was founded in 2006, global spending on malaria was only a few hundred million dollars a year, and approximately a million people were dying from mosquito bites annually.

Through a massive global effort – including $3 billion in annual funding, led by the U.S. and U.K. governments, the Global Fund to Fight AIDS, Tuberculosis, and Malaria, the World Bank, the private sector and philanthropists - the rate of malaria deaths in Africa has been cut in half in under a decade. According to the World Health Organization, an estimated 3.3 million lives have been saved since the year 2000 from malaria alone.

 

Malaria funding now vs next

Planning for a Rainy Day

The danger with malaria - the thing that keeps us malaria fighters up at night - is that if you lose focus, even for a single rainy season, the disease can come roaring back with devastating consequences.

There have been 75 documented instances of malaria resurgence from the 1930s to the year 2000, and nearly all of them were associated with the weakening of malaria control efforts. If we stopped investing in malaria control today, it would cause a massive humanitarian crisis, claiming millions of lives, and undo the hard-fought gains we’ve made in the past decade.

As the burden of malaria continues to be reduced, we need to shift from catalytic “scale up” funding models to sustainable, long-term approaches that will enable us to end the disease. That means diversifying the sources of funding so that the continued commitment of international donors is buoyed by growing domestic and regional investments, as well as innovative financing approaches. It also means using better data to find efficiencies that will stretch and strengthen the impact of malaria spending at the country level.

Put Your Money Where Your Malaria Is

We often say that malaria is both a cause and a consequence of poverty. But the reverse is also true: malaria control is equally a cause and consequence of economic growth. It’s not just geography that caused malaria to be eliminated first in the United States in 1951 and most of Europe by 1975 - it was equally the result of economic growth, development and increased spending on health and infrastructure.

The current slate of countries moving toward malaria elimination – mostly in Asia and South America – are already covering the bulk of the expense themselves: almost 80 percent of interventions are self-financed, according to a recent analysis by UCSF’s Global Health Group and Cambridge Economic Policy Associates. 

 

Malaria funding vs deaths

In Africa, however, most countries still fall short of the self-declared “Abuja target” of dedicating 15% of domestic budgets to improving health. As “Africa Rising” moves from rhetoric to reality and economies on the continent continue to grow, Africa has the wherewithal to finance an increasing share of its malaria elimination ambitions. And it has powerful financial incentive to ensure the work continues - a recent study by Accenture estimated the present-day economic value (i.e. profit) of continued investment in malaria control in Africa at more than $322 billion between now and 2035, due to the tremendous health and productivity gains that would result.

Endemic countries also have the opportunity to stretch their budgets by working smarter. To the extent that countries can draw on good timely data to inform program decisions, they can save money by targeting the appropriate mix of interventions by region and setting. Zambia and Zimbabwe, for instance, have saved millions of dollars by using malaria risk-mapping to optimize their net and insecticide spraying programs.

Particularly as countries reduce their malaria burden, one-size-fits-all, national-scale approaches may no longer apply. Namibia, a country moving toward elimination, has used malaria and mobility data to develop a more sophisticated, spatially targeted malaria program.

The Future of Funding

Regional financing mechanisms are emerging for countries, companies, and philanthropists to invest in malaria control and elimination in their own backyards. Asia-Pacific has set the ambitious goals of eliminating drug-resistant malaria by 2020, and all malaria by 2030. To help finance the efforts, the Asian Development Bank and the Asia Pacific Leaders Malaria Alliance this year set up a regional trust fund to solve this pressing regional challenge.

Mechanisms for nontraditional donors to play a part in eliminating the disease are growing as well. In Indonesia, a small group of high net worth individuals have pledged to co-invest alongside the government and Global Fund in health priorities, while in the Philippines and Ghana companies with large local operations – the Pilipinas Shell Foundation and AngloGold Ashanti – have managed Global Fund malaria grants working hand-in-hand with government agencies.

Innovative financing efforts, including concepts such as development impact bonds, also have the potential to contribute. Creators of The Mozambique Malaria Performance bond aim to establish a sustainable new funding source that can also improve the efficiency of malaria programs through a pay-for-performance model.

It’s an attractive concept: private investors front the costs of malaria control interventions to be repaid by a group of government and private-sector partners who reap the rewards of successful malaria control, including healthy citizens, employees and consumers. But we have yet to see investors step up to participate in such an instrument vehicle. If these models take root, malaria could evolve from being “the best humanitarian investment” to an actual investment opportunity—one that pays a dividend to those who contribute.

Achieving the historic goal of malaria eradication requires endurance. To sustain and extend the gains of the past decade, the global community must commit to providing predictable, sustainable, long-term support.

Our success in fighting malaria over the past decade has been built upon a solid foundation of funding, and the continued support of the U.S., U.K. and Australian governments; as well as institutions such as the Global Fund and the World Bank, will be essential to finishing the job. But we also need endemic countries and regions to commit to shouldering an increasing share of the costs as we move toward malaria elimination.

In the end, it will not be one sector or government that will finally eradicate malaria. It will be a global success—one we should all be proud to have contributed to.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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5 challenges to end malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-4-data-mobile https://www.malarianomore.org/news/entry/challenge-4-data-mobile

How the mobile revolution in Africa is transforming global health

When I first moved to West Africa, back in 2009, you could travel to the most remote, rural villages – places without power, running water, or any other modern conveniences – and you would invariably find Coca-Cola. Somehow the familiar red-and-white brand had solved the distribution and marketing challenges of reaching these ends-of-the-earth consumers.

In those same remote villages, you can also find some of Africa’s highest-tech companies – mobile providers like MTN, Tigo, Airtel, Vodacom and Safaricom. Africa has leapfrogged the power line and the PC and gone directly to mobile phones. By the end of 2015, there will be an estimated 1 billion mobile phone accounts in Africa – one for nearly every man, woman and child on the continent.

First Disease Beaten By Mobile

In our first challenge (“Find the Parasite”), we talked about the importance of rapid diagnostics to locate the malaria parasite in people. What is a diagnostic test result but a plus or a minus, a one or a zero? It’s a bit of data. But in many malaria-endemic countries, that data used to just sit in stacks of paper to be collected every so often by health authorities. When you combine this data with rapid reporting via mobile phones, you have the makings of a revolution in global health.

Of all the tools in the malaria fight (including the obvious ones such as nets, testing, treatment and spraying) mobile phones may be the ones that tip the balance toward ending this disease. That’s why at Malaria No More we’ve been bold in proclaiming that malaria can be the first disease beaten by mobile.

A Swiss-Army Knife for Malaria

Sounds ambitious, but when you look at the problems we have to solve – from case detection and response, to stock management, and health education – mobile is at the center of the solutions time and again. It’s the Swiss Army knife of the malaria fight, helping to solve and accelerate a wide variety of other solutions. Here are a few examples of how mobile and data are already transforming the malaria fight.

The Novartis-led SMS for Life program has demonstrated the potential of mobile to address stock outs and ensure that people have malaria drugs when and where they need them. The pilot program focused on three districts in Tanzania. When it started, 26% of public health facilities were completely stocked out of malaria drugs at any given time. That means that parents had a one-in-four chance of showing up at a clinic with a sick child only to find that they didn’t have a dollar’s worth of life-saving treatment on hand.

To address the problem, under the umbrella of the Roll Back Malaria Partnership, Novartis and its public and private partners set up a simple, SMS reporting system that enabled health workers and pharmacists at public health facilities to record and report their stock levels on a weekly basis. This made it possible to anticipate shortages and distribute malaria drug supply more efficiently. Six months later, less than 1% of the facilities were stocked out of malaria drugs: a 97% reduction in stock outs through better and faster information flows. SMS for Life has now been expanded to several other African countries including Ghana, Kenya and Cameroon.

 

Mobile swiss army knife for malaria

In a similar fashion, mobile phones may be the key to solving the challenge of counterfeit and stolen malaria treatments. Nigeria is the epicenter of the malaria challenge, accounting for nearly a quarter of the world’s malaria burden. As the market for antimalarial treatments has grown, so too has the attraction for counterfeiters. Recent estimates suggest that nearly 40% of all antimalarials on the market are counterfeit.

The challenge is compounded by the fact that most Nigerians don’t get their treatments from public health facilities. Eighty percent of people go to the private sector for treatment. And this isn’t your corner Walgreens we’re talking about. In Nigeria, it’s not uncommon to see malaria drugs sold alongside open-air butcher stands and car parts in public markets.

The solution to this problem? You guessed it - mobile. Working with companies such as Sproxil, PharmaSecure and mPedigree, the Nigerian government now requires that every antimalarial drug (and antibiotic) carry a label that consumers can scratch off like a lottery ticket and text in for free to confirm their drug is authentic and safe. Read more about Sproxil’s efforts to combat counterfeiters here.

This scalable use of the technology is revolutionizing the fight against counterfeits, and even helping authorities to track down contraband drugs. Malaria No More is working with a group of partners to go a step further: to explore how this data – a real-time sample of antimalarial consumption – can be used to draw fresh insights that can inform public health decision-making to save even more lives.

The Big Benefits of Data

A study in Kenya presents another compelling example of leveraging non-health data to fight malaria.

Caroline Buckee of the Harvard School of Public Health worked with Kenya’s largest mobile operator to analyze anonymized mobile phone usage records from 15 million consumers to track human migration patterns. Researchers then combined this migration map with regional malaria incidence data to identify how malaria travels around the country via human carriers.

Unsurprisingly, most of the malaria emanated from the high-transmission areas along Lake Victoria on Kenya’s western border.  But the data also spotlighted unusually high migration from the Lake Zone region about 50 miles inland to the western highlands region.

A few clicks of a Google map reveal that the western highlands are host to massive and bustling tea plantations that serve as a kind of bus depot for malaria transmission. Infected workers came from the Lake Zone to the highlands, where mosquitoes picked up the parasite and infected fellow plantation workers, who in turn transported the parasite back to their home communities farther inland.

These data-driven insights can help direct resources and interventions to make the malaria fight more effective. For example, eliminating malaria in the Lake Zone might cut off the source of infections in the highlands – even if you didn’t run a large-scale elimination program in the highlands themselves.

Mobile Aids Elimination

If anything, harnessing the power of mobile and data becomes more important as countries move toward malaria elimination. As the scale of the problem shrinks, the need for timely and precise surveillance data only grows. Vital elements such as real-time reporting of cases and accurate intervention mapping are now possible thanks to web, mapping, mobile and data analytics tools.

As you move toward the end game of elimination, countries must be able to track and respond to every case immediately to prevent it from spreading. They set up a sort of SWAT-team approach (painful pun intended): rapid-response systems in which health workers immediately report cases and teams show up to test and treat people in a perimeter around the infection to contain the spread of the parasite.

Even more so than Coca-Cola, that gives us something to smile about.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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5 challenges to end malaria, Mobile and Malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-4-data-mobile-ashifi-gogo-ceo-of-sproxil https://www.malarianomore.org/news/entry/challenge-4-data-mobile-ashifi-gogo-ceo-of-sproxil

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge 4 (link to post) looks at ways technology and data can be used to fight malaria. Ashifi Gogo is the head of Sproxil, a company that uses mobile phone technology to combat dangerous counterfeit malaria medication.

1) Many people aren’t aware of the major threat counterfeit drugs pose, can you briefly describe the problem and how mobile authentication, such as Sproxil, helps fight it?

Drug counterfeiting, while particularly prevalent in emerging markets, is a global disease that threatens the safety and well-being of all citizens. 700,000 people die every year from fake anti-malarial and tuberculosis drugs alone: it is the equivalent of the entire population of Boston disappearing in a single year.

By leveraging the increasing popularity of mobile phones, we developed a simple, but powerful and secure SMS system: Mobile Product Authentication™ (MPA™). We partner directly with manufacturers and distributors to append security labels with a scratch-off panel on each product. At point of sale, a consumer will scratch off the panel to reveal a unique, single use code that they SMS to our phone number for free. The consumer instantly receives a response back confirming that the product is genuine or warning that it is suspicious. Our 24/7 help desk, which supports major local languages, is available for reports of counterfeiting activity and for questions relating to the product or solution.

To further reduce access barriers, we have multiple channels for verification: mobile apps (available on iPhone, Android, and Blackberry 7), web apps and our help desk.

2) You’re working to integrate Sproxil into more countries. Where do you provide service currently, and where do you plan to expand?

We have operations in Ghana, India, Kenya, Nigeria, and the U.S. and can execute projects on six major continents. In an effort to stay ahead of counterfeiters, we do not disclose our plans for expansion.

3) Beyond preventing counterfeits, do you see other ways to leverage this data to improve health?

Our technology was developed to be flexible and scalable. By creating direct communication channels between our clients and their patients, MPA can help foster healthier lifestyles. Our technology can support medical adherence programs, message patients with expiration reminders and health and wellness information or connect them with health care providers or other experts and even send special coupons or recommendations for other wellness products.  The opportunities for improving health by connecting patients with the appropriate resources make the possibilities limitless.

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5 challenges to end malaria, Mobile and Malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-3-block-transmission https://www.malarianomore.org/news/entry/challenge-3-block-transmission

The secret to ending malaria could be protecting mosquitoes from humans

As villains go, the mosquito is well cast. The tiny pest is unique in nature in two important respects. First, it has no redeeming value to the broader ecosystem (the name of the particular breed that transmits malaria, “Anopheles,” actually means “useless” in Greek); and second, the mosquito is by far the deadliest creature on the planet to human beings, claiming 725,000 lives a year—principally to malaria, but also to diseases including dengue fever and West Nile virus.

Even Disney, the company that made ants and lobsters lovable, has it in for the mosquito. In a now-famous 1943 animated short titled “the Winged Scourge,” a Disney narrator brands mosquitoes “public enemy number one” for transmitting malaria, and cheers as the Seven Dwarves gleefully pump insecticide and stomp the bug.

Our first two columns explored how finding the parasite(link) and completely curing(link) infected people are two of the keys to ending this disease. The missing piece is to block transmission and stop the endless shuttling of the parasite back and forth between man and mosquito.

You see, for malaria, the transit between mosquito and man isn’t just a joy ride—it’s an essential step in reproduction. By blocking transmission you isolate the mosquito and interrupt that process. In mosquitoes, the parasites die quickly due to their host’s short life spans; and the ones in humans stay contained until you can eliminate them with medication.

The classic approach to blocking transmission is to protect people from mosquito bites using bed nets or insecticide sprays. And make no mistake, these tools have been extraordinarily effective: a major factor in saving 3.3 million lives from the disease since 2000.

Rethinking the Problem

But to break the back of transmission, we have to rethink the problem. We must move beyond vilifying the mosquito—and the key may be protecting mosquitoes from humans.

Surprised? You shouldn’t be. Consider that mosquitoes only carry the malaria parasite for up to 30 days—a mosquito’s maximum lifespan—while humans can carry the parasite for decades if left untreated. And where mosquitoes can only travel a mile or two on their tiny wings, humans circle the globe transporting the parasite like carry-on luggage. So if we’re looking for someone to blame for malaria transmission, we must start by taking a hard look in the mirror.

The surest way to avoid getting malaria from mosquitoes is to stop giving it to them. That’s why a new generation of treatments that completely eliminate the malaria parasite from the human body will be so important (for more, read Challenge 2: Complete Cure). But it is only one of the novel approaches that will make it possible to stop transmission.

 



Next Generation Protection

Soon, the tried-and-true bed net may be joined by new vector-control technologies that use radar-jamming molecules to disguise humans from mosquitoes. That’s the goal of a technology called Kite Patch, which took the crowd-funding site Indiegogo by storm. Worn on your clothes, this small sticker is a spatial repellent that blocks a mosquito’s ability to register carbon dioxide. In effect, it acts like Harry Potter’s cloak of invisibility, making people virtually undetectable to mosquitoes. (Read more about the Kite Patch technology and what it could mean for malaria.)

This past summer, the pharmaceutical company GlaxoSmithKline registered for regulatory review of the first partially effective malaria vaccine—called RTS,S—and hopes for a WHO seal of approval as early as 2015. In clinical trials, the vaccine reduced the number of malaria episodes by a quarter in infants immunized and cut in half malaria cases in older children (toddlers) - low by vaccine standards, but unprecedented in terms of malaria.

But even as we celebrate this milestone – the first vaccine against a parasite – the focus of research is moving beyond only protecting individual people against malaria symptoms (as RTS,S does) to blocking transmission.

New vaccine approaches target two “choke points” when parasites are at their fewest in number during their complex life cycle: the transitions from mosquito to man, and from man to mosquito. These potential vaccines could effectively hold the line against onward transmission of the parasite, stopping malaria dead in its tracks.

Despite the PR campaign against mosquitoes, the goal of malaria control has never been to eradicate the insect, but only to control it as a way to get at our true adversary: the parasite. Little did we suspect that the key to eradicating malaria around the globe could involve making the mosquito an asset in the malaria fight.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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5 challenges to end malaria, Mosquito Nets, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-3-block-transmission-grey-frandsen-kite-patch https://www.malarianomore.org/news/entry/challenge-3-block-transmission-grey-frandsen-kite-patch

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge 3 addresses new technologies and approaches that are in development to block the transmission of the malaria parasite between humans and mosquitoes. To learn more about one such innovation, we spoke with Grey Frandsen from Kite Patch, a sticker that protects humans from mosquitoes by disrupting the insect’s ability to detect humans.

 

1. In our eco-conscious age, a lot of people are wary of putting chemicals on their skin to repel mosquitoes. But mosquito bites are an annoying problem in the U.S., and a deadly one in parts of the world such as Africa and Asia where the pests carry life-threatening diseases, including malaria and dengue fever. Can you tell us how Kite Patch works to protect from mosquitoes without using the traditional skin contact of insect repellents?

Kite Patch is a small, beautifully-designed little “sticker” that creates something akin to an invisibility cloak, or as some suggest, a defense shield, around our bodies with spatial compounds emitted from the materials on the sticker. This product form is being designed to emit a certain level of those spatial compounds over a period of time so that the compounds hover and swirl around the body with movement and wind, and travel away from our bodies in varying distances to intercept mosquitoes as they track toward us. Once mosquitoes come into contact with these compounds, they lose the ability to detect carbon dioxide and sense skin odors – the two primary mechanisms by which they track us.

We’ve designed Kite’s brand to capture the spirit of freedom and joy – something we believe will be the result of new technologies and products, such as Kite Patch, that will lift both the burden of disease and the burden of the fear of disease.

 

2. Kite Patch coming to fruition was a collaborative effort involving several different groups pitching in on funding. Can you tell us about the process of getting this innovation from the idea to the production stage, and where you’re at now?

Kite Patch absolutely is a story about collaboration. It’s also the result of a new model developed by ieCrowd to transform innovative discoveries into solutions to global challenges. This model brought together the innovative discovery, the capital, the development partners and experts, the team, and the range of stakeholders that now make up the large, global Kite campaign.

People may know the Kite Patch from our Indiegogo campaign. Last year we launched a crowdfunding effort to raise awareness and support for a specific field test of some of our Kite Patch prototypes. We wanted to expand the number of people involved in our development process and inspire people to play a role in getting a new technology to market.

The result was amazing. The campaign went viral and Indiegogo named it one of the top five campaigns ever. We enjoyed support from around the world. Over 500 publications ran original stories about our campaign, the technology, our process for commercializing this technology, and how we branded and marketed the campaign and the product itself.

As for the product itself, Kite technology stems from scientific findings initially discovered at the University of California, Riverside (UCR) with assistance from The Bill & Melinda Gates Foundation, and the National Institutes of Health (NIH). ieCrowd exclusively licensed the technology from UCR, and has, since then, furthered the science into a range of new technologies, in order to advance disruptive products such as Kite Patch. Kite products - ranging from new mosquito repellents to spatial attractants - feature spatial and non-spatial active ingredients.

The next major step is to get Kite Patch to the field, to markets, and into the hands of people who need it the most. To do so, we’ll continue to build partnerships around the world with those who share our passion for eliminating this horrible disease.

 

3. Some readers may think a sticker is a novelty item, but you see Kite Patch having major implications on the field of public health. Can you tell us how far-reaching you hope Kite Patch will be?

We want to be humble about the role Kite technology and products can play, but we do know this: while our mock-ups make it look cool and pretty (and don’t those kids in the below Kite Patch video look cute? Those are mine!), the Kite technology platform is being developed to support what we believe can be one of the most powerful weapons platform in the fight against mosquito-borne diseases. We have a world-class team working 24/7 to build a powerful platform of actives that can ideally be deployed around the world in a range of applications – all of which will have minimal impact on our health and the health of our environment.

 

WATCH: Kite Patch in Action

 

Specifically, we’re working on repellents and attractants that can be deployed in any number of product forms that will play important roles in public health and disease intervention efforts globally. We pay attention to every detail and we’re designing each of our products with history and current technologies and needs in mind. Most importantly, we have opened our development process to people around the world and continue to build our technology and products with significant inputs and feedback from the Kite crowd.

Our technical foundation is strong, and ieCrowd’s system for deploying disruptive new solutions like Kite Patch is ready for action. We’re excited about the prospects of the Kite platform, and with the help of the crowd, amazing partners, and the world’s best team, we have no doubt that it will be among the leading tools to fight against malaria and other mosquito-borne diseases.

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5 challenges to end malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/best-fiends-malaria-no-more https://www.malarianomore.org/news/entry/best-fiends-malaria-no-more

While most of the world thinks of mosquitoes as blood sucking, disease-spreading pests, there’s a new guy in town who’s on a mission to redeem the rep of his fellow mosquitoes.  Meet Edward, the handsome, malaria-fighting skeeter who happens to be one of the stars of Seriously’s new mobile game, Best Fiends. 

The Best Fiends are a pack of fun-loving creatures who spend their time fighting slugs to protect the citizens of Minutia.  But Edward has his own side gig – educating the world about malaria and helping Malaria No More to beat back this awful mosquito-borne disease to protect humans!  Getting by on a diet of coconut water instead of blood, Edward changed his ways, and has developed a whole arsenal of tools to help prevent and treat the spread of this disease.

Want to help Edward end malaria?  Visit our Edward page for a whole list of ways you can support the malaria fight, and make sure to download the game on your iPhone or iPad!

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Mobile and Malaria, 2014--T:: https://www.malarianomore.org/news/entry/challenge-2-complete-cure-roger-waltzman-novartis https://www.malarianomore.org/news/entry/challenge-2-complete-cure-roger-waltzman-novartis

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge #2 focuses on the development of a single-dose cure for malaria, so we sat down with Dr. Roger Waltzman. Waltzman works for the Malaria Initiative at Novartis, the maker of one of the top malaria treatments on the market.

Q: Novartis is a pioneer in the research and development of malaria treatments. What is the quick history of innovations Novartis has been a part of?

A: Novartis is in the fight against malaria for the long haul. Together with Chinese partners, Novartis developed the first artemisinin-based combination therapy (ACT), today’s gold standard in malaria treatment, and launched the first child-friendly, dispersible formulation developed jointly with Medicines for Malaria Venture. More recently, we launched another new formulation which reduces the pill burden for adults; this helps to ensure patients follow through with their full treatment course. Today, Novartis partners with the best institutions and intensifies its research efforts to develop new compounds against malaria to eventually eliminate the disease. With two compounds in Phase 2 clinical development and one drug target in pre-clinical research, Novartis scientists are building one of the most promising malaria pipelines in the industry.

Q: What kind of treatments will it take to eliminate malaria?

A: A two-pronged approach is required to eliminate malaria. First, new treatments must be developed that attack the malaria parasites in novel ways in case resistance against current treatments spreads. These treatments will also need to provide a “complete cure”. Second, within malaria-endemic countries, a large proportion of people with malaria do not show malaria symptoms and therefore do not seek treatment for their infection. They constitute a reservoir of malaria parasites that can be transmitted to other, more vulnerable populations, therefore targeting and treating these individuals is central to achieving the goal of malaria elimination.

Q: What is a “complete cure” for malaria? How is it different from what we have today?

A: “Complete cure” implies that the treatment not only targets the parasites in the blood in their asexual stage, which is the stage when symptoms of malaria appear, but also in their sexual stage (gametocytes). Gametocytes can be harbored in the human without provoking any symptoms, and transported upon a mosquito bite, infecting other humans. A complete cure would enable a patient to be cleared from all malaria parasites. It would also stop transmission to other humans. Current treatments do not necessarily offer the potential for a complete cure.

Q: Why is a single-dose treatment important and how do you see it affecting malaria prevalence globally?

A: Developing a new combination, similar to today’s three-day ACT treatment, which is powerful enough to treat malaria in one single dose, would enable the patient to take the entire treatment at once, virtually eliminating the risk of insufficient treatment. Indeed, with current treatments patients sometimes save tablets for other family members or friends or in case they are infected by malaria again, not realizing they may be inadequately treated. Also, parasites can become resistant to treatments when dosing is inadequate. A single-dose treatment has the potential to ensure complete and effective treatment for patients. In addition, depending upon its efficacy and safety, the treatment could be given to people who show no symptoms but harbor malaria parasites in their blood, and can therefore transmit malaria. Ultimately, treatment of asymptomatic people could help eliminate the disease in broad population groups, potentially leading to malaria eradication.

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Malaria Treatments, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-2-complete-cure https://www.malarianomore.org/news/entry/challenge-2-complete-cure

Inventing a Wonder Drug to Win the Malaria Fight

The story of malaria control is the story of the promise – and peril – of wonder drugs. With hundreds of millions of people infected with malaria around the globe every year, effective treatment may be the difference between ending the disease and humanitarian disaster.

Quinine, the first antimalarial, was discovered in the bark of the cinchona tree in the foothills of the Andes Mountains back in the 1600s. But it was hard to produce and administer, and there still was no reliable global supply by World War I.

Finding a cheap, reliable alternative to quinine that could be mass-produced became a military imperative during World War II. America suffered humiliating defeats “not because the ammunition was gone,” The New York Times reported, “but because the quinine tablets gave out.”

However, the synthetic drugs that emerged from that furious R&D effort – most notably chloroquine – were little match for the fast-evolving parasite, which developed resistance in under a decade.

Progress Threatened

Our current front-line treatments for malaria, called artemisinin-based combination therapies (or ACTs for short), underscore the arms race between science and parasite. ACTs have been wildly successful in saving lives – a true wonder drug by any definition – but their effectiveness may also be cut short by resistance.

First touted for its curative powers in an ancient Chinese medical book dating back to 168 BC, artemisinin was finally brought to scale globally by Swiss healthcare company Novartis, which received WHO international approval for its drug in 1999. Global funders threw their weight behind ACTs five years later, and today more than 280 million ACT treatments are distributed every year in Africa alone.

But resistance is once again threatening to rob us of our best tool in the malaria fight. Just as chloroquine resistance emerged along the Thai-Cambodia border back in the 1960s, first signs of artemisinin resistance have now been documented in the region. If it follows the same pattern as past resistance – emerging across Asia, in India, making the leap to Africa – it could potentially cost millions of lives.

History has shown that containment isn’t an option: Only by eliminating malaria in Asia-Pacific can we staunch the spread of resistance. So the Greater Mekong subregion will be ground zero for a renewed global eradication effort.

In Search of a Solution

The race is already on to develop the next generation of wonder drugs—this time tailor-made for eradication. Such a drug would have four key features.

 



First, it would be a single-dose treatment. The pharma industry talks about the “pill burden” – the total number of pills someone has to take to complete a full course of treatment. The more pills, over more days, the greater the chance that a patient will stop midway and fail to be fully cured.

Malaria treatment currently requires between three and 14 days of treatment, depending on the strain of the parasite. Getting people to take all their pills is complicated by the fact that the drugs are so fast-acting and effective that malaria symptoms may subside after the first or second day, leading people to think they’ve been treated, when in fact trace amounts of the parasite may still be hanging around in their bodies waiting to mount another attack. A single dose treatment would ensure that everyone who is treated is parasite-free.

The second feature of a new wonder drug is that it will be a “complete cure.” Malaria is so challenging in part because the parasite plays hide and seek in the human body: traveling in the bloodstream, lodging in the liver, the brain – even bone marrow, as a recent study highlighted.

Before you can hope to eliminate malaria in a community of people, you must be able to effectively eliminate it in a single person. A complete cure treatment would wipe out the parasite at every stage of its lifecycle, ensuring zero risk of passing the parasite along to others.

The third feature is what we call a prophylactic effect. Essentially, you want a drug that will remain in the body for a period of time to prevent a person from developing another case of malaria if bitten again by an infected mosquito.

And finally, the new treatment would have a high barrier to resistance, so even as you scale up use it’s able to maintain its effectiveness. This means developing an arsenal of molecules that attack the parasite in novel ways, and then using drugs in combination to stave off resistance. New malaria drugs are a great investment, but they’re expensive to develop, so we must ensure they last.

In the Pipeline

The good news is we’re well on our way to making a new slate of wonder drugs (or “one-der” drugs) a reality. Supported by a product development partnership called Medicines for Malaria Venture out of Geneva, the malaria community and pharma industry leaders including Novartis, Sanofi, and GlaxoSmithKline have started clinical trials for treatments that will make ending malaria a reality.

As one example, Novartis has fast-tracked its first non-artemisinin based single-dose drug candidate, called KAE609, and recently published results showing that it was able to clear malaria parasites in adults in 12 hours on average. Read more about the quest for a malaria wonder drug here.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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Malaria Treatments, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/femi-kuti-answers-questions-malaria https://www.malarianomore.org/news/entry/femi-kuti-answers-questions-malaria

Femi Anikulapo Kuti has been able to stand tall as an icon in the music industry without being overshadowed by the colossal image of his legendary father, Fela Anikulapo Kuti. Over the years he has blended jazz and funk with afrobeat to create a cocktail of unique indelible sounds of afrobeat, and this has earned him four nominations for the prestigious Grammy Awards.

Today Femi Kuti joins Malaria No More to have a Twitter conversation on malaria, music and the Nigerian society. It promises to be an enthralling conversation as Femi is vocal in his opinions. To join this conversation, follow the Malaria No More Twitter account in Nigeria: @MalariaNoMoreN1 and tweet your questions to Femi Kuti as from 11AM - 12PM ET using the hashtag #AskFemiKuti. Femi Kuti is currently one of the ambassadors for the Malaria No More campaign in Nigeria.

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2014--T:: https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-spotlight-on-alere https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-spotlight-on-alere

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge #1 focuses on finding the parasite, so we sat down with Duncan Blair, PhD. Blair is the Director of Public Health Initiatives at Alere, the maker of one of the top malaria diagnostic tools on the market.

 

Q: Why are malaria RDTs a focus for your business?

With Alere being the global leader in rapid diagnostic tests for communicable diseases it would be almost impossible for us not to be involved in the malaria fight. Approximately half of the world’s population live in malaria-endemic areas, and consequently, are at risk of infection. With over 200 million infections and over 600,000 deaths a year, the risk to individuals and the burden on health care systems are enormous. To treat malaria appropriately and, just as importantly, to know when not to treat for malaria, requires accurate diagnosis. For decades, the only option for malaria diagnosis was microscopy, but microscopy is extremely challenging to implement with quality due to significant needs for complex equipment, electricity, water, well-trained and well-remunerated staff and many other reasons. The advent of the rapid diagnostic test (RDT) for malaria greatly improved our ability to diagnose malaria simply and effectively. RDTs are high quality, simple and quick tests that can be performed with just a few drops of finger-stick blood at the point of care and without any ancillary equipment. The benefits that the introduction of high-quality and properly deployed malaria RDTs have brought to individuals, to health care systems and to entire communities, is immeasurable.

Q: What are some of the new testing developments you’re working on?

We are always looking at ways to improve products or to fill a missing diagnostic need with a view of improving patient and health system outcomes. I think that we find ourselves at a time when malaria elimination is within reach and many of the tools needed to achieve that goal already exist, but not quite all of them. One of the missing pieces of the puzzle is a simple, affordable test capable of detecting the malarial parasites in asymptomatic patients. No such test exists today, but it will be critical for elimination, as we will need to find and treat patients who have no fever and no visible symptoms, but who do have circulating parasites and are therefore acting as a reservoir for future reinfection of the community. Alere is actively looking at developing just such a test.

Q: What are the key challenges you must solve to make this next-generation test a reality?

What we are talking about here is developing a test whose performance is many times better than the best tests currently available, which still meets our exacting quality standards and which can be reliably and sustainably manufactured, delivered and effectively deployed at accessible prices. We’re optimistic we can deliver that, given the great range of technologies at our disposal within Alere and the fantastic teams of dedicated and innovative people we have in R&D and manufacturing. So there may be challenges ahead, but we are very confident that we can rise to meet those challenges.

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5 challenges to end malaria, Alere, Malaria Tests, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-find-the-parasite https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-find-the-parasite

You can't beat an opponent you can't see

Malaria thrives on misinformation. It always has. Even the word malaria is a misnomer. It’s Italian for “bad air,” because the Romans attributed the seasonal sickness (that killed at least four Popes, and probably the poet Dante) to noxious fumes coming off the swamps. It wasn’t until 1897 that Dr. Ronald Ross confirmed the mosquito as the vector that spreads the disease.

And misinformation is one of the big reasons malaria continues to kill a child at the rate of one every sixty seconds. Solving the information challenge is going to be key if we’re going to end this disease, and no piece of information is more vital than knowing who is carrying the parasite and who isn’t.

THE HIDDEN MALARIA CHALLENGE

While there are more than 200 million malaria cases every year – that is, people who are getting sick from the disease – it is estimated that there are five times as many people carrying the parasite in their bodies at any given moment – a ticking time bomb of illness and infection.

That amounts to more than one billion people – one out of every seven people on the planet – who are potentially infected with the malaria parasite, jeopardizing their health, hampering their productivity and making them a source of infection for their families and communities. And, most of them have no idea they’re carrying the potentially deadly disease!

 



The biggest host of the malaria parasite is healthy people, not sick people or mosquitoes.

The insight that sick patients showing up at clinics are only the tip of the malaria iceberg underpins emerging strategies for eradicating the disease. Simply put: you can’t beat malaria if you can’t find it. So any attempt to eradicate the disease must start with developing the diagnostic capabilities to find and free the roughly one billion people living with the parasite in their body and stop them from transmitting.

It may sound like a daunting task, until you consider how far we’ve come in recent years – and how fast.

THE DIAGNOSTIC REVOLUTION

Until 2010, there was no practical way to get a timely, accurate diagnosis for malaria. If you had a fever and wanted to be tested for malaria, you had to travel a long distance – sometimes tens of miles on foot – to find a hospital or clinic equipped with an expensive microscope and a trained lab technician. You had to take a blood slide, then wait several hours for the result – hoping that the lab technician read it right.

It was impractical, and people simply didn’t do it.

In many African languages, the words for “malaria” and “fever” are the same. It’s easy to understand why. Absent practical diagnostics, doctors simply treated every fever as if it was malaria and hoped for the best.

Then came the breakthrough: the rapid diagnostic test, or RDT. This simple, fifty-cent, finger-prick blood test can tell you in a matter of minutes with better than 99% accuracy if your fever is malaria.

The RDT has revolutionized the malaria fight, enabling lightly trained community health workers operating on the far reaches of the health system to test patients for malaria. Negative results are as important as positive ones as they direct doctors to consider other top killers, such as pneumonia and upper-respiratory infection. There are now more than 200 million RDTs distributed across Africa each year.

NEXT GENERATION TESTS

Today, we need to revolutionize diagnosis yet again, this time with a focus on identifying asymptomatic cases and guiding treatment.

Current RDTs have a sensitivity of 200 parasites per microliter of blood – sufficient for identifying all cases in sick people. But finding low-levels of the parasite in asymptomatic patients is like an elaborate game of hide and seek. To do it, we need a new generation of simple, portable, inexpensive diagnostic tests that are 10 times more sensitive, detecting malaria at levels of 20 parasites per microliter or even lower.

Fortunately, through innovative public–private partnerships led by groups like the Medicines for Malaria Venture (MMV) and Seattle-based partner PATH, we’re well on our way to developing next-generation diagnostic tests.

Other next-generation diagnostics will potentially help solve some of the treatment challenges that stand in the way of elimination. Efforts to tackle the dominant strain of malaria in Asia and South America, known as P. vivax, have been hamstrung by the fact that some people have an adverse reaction to the drug recommended for completely clearing the parasite, due to a common inherited trait known as G6PD enzyme deficiency.

The development of diagnostics to identify individuals with G6PD deficiency would ensure better use of current drugs and potential new single-dose treatments, such as tafenoquine, currently in development by GlaxoSmithKline and MMV.

Armed with new diagnostics, we’ll be in a position to take the fight to the parasite. Instead of passively waiting for sick people to show up at clinics, we can go on offense: actively testing and treating entire communities to find and root out malaria, while ensuring the type of treatment provided to patients will be safe and effective.

Which sets up the next of our challenges - check back in next week to read about another big innovation in the malaria fight: developing a complete cure!

Q&A: Read about Malaria No More’s partner Alere and their quest for new diagnostics here.

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This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

Intro: Going on Offense 

Challenge 1: Find the Parasite

Challenge 2: Radical Cure (10/8/2014)

Challenge 3: Block Transmission (10/14/2014)

Challenge 4: Data & Mobile (10/21/2014)

Challenge 5: Fuel the Fight (10/28/2014)

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Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/solve-for-m-5-key-challenges-to-ending-malaria https://www.malarianomore.org/news/entry/solve-for-m-5-key-challenges-to-ending-malaria

After a century of playing defense, it’s time for the malaria fight to go on offense

In 1897, Dr. Ronald Ross – an Indian-born, British surgeon who counted poetry, mathematics, and songwriting among his other passions - made a medical discovery that would change the course of history.

Stationed in Secundebad, a monsoon-drenched city in Central India, Dr. Ross identified the malaria parasite in the gut of a dissected Anopheles mosquito. His discovery confirmed that the winged pest was in fact the vector responsible for spreading one of the oldest, deadliest, and most devastating diseases on the planet.

Dr. Ross was knighted and awarded a Nobel Prize for his efforts, and deservedly so: His discovery laid the foundation for the modern fight against malaria.

Historic Progress

We’ve made significant strides since Dr. Ross’ time. Malaria has been eliminated throughout most of the developed world, including the United States in 1951. And progress is accelerating: Just since 2000, we’ve cut global malaria deaths by half, saving 3.3 million lives - most of them children and pregnant women in Africa.

However, the work is far from done. A child still dies every minute from a mosquito bite, and more than 200 million people are afflicted with the disease each year, keeping adults out of work, children out of school, and stifling the growth of developing economies.

Based on the progress of the past decade, there is a growing determination among the global health community to eradicate the disease once and for all, recognizing that the only way to ensure zero malaria deaths is to have zero malaria.

Going on Offense

So what will it take to finish the job?

We need to rethink the malaria problem in as radical a way as Dr. Ross did more than a century ago. For all our progress, the prevailing approach to controlling malaria has fundamentally been about playing defense: trying to prevent mosquitos from biting and treating people when they’re sick so they don’t die. Don’t get me wrong. That has been the most cost-effective way of tackling a complex problem, going after the “low-hanging fruit” and bringing down the number of cases and deaths dramatically.

But to win this fight, we need to take a “parasite’s-eye” view of the problem. We must attack the malaria parasite where it lives - in the human reservoir – with aggressive new approaches to find, clear, and prevent onward-transmission of malaria, even in asymptomatic carriers of the disease. In short, we must go on offense.

As part of that approach, we need to confront one of the newest and most urgent threats to the advances we’ve made against malaria: Resistance in Asia to the frontline treatment of the disease, artemisinin. The last time drug-resistant malaria developed in that part of the world, it spread to India and Africa, robbing us of chloroquine as an effective tool.

If that happens again, it could cost millions of lives, since we are at least 4 to 5 years away from developing a viable treatment alternative.

The Path Forward

We find ourselves at another watershed moment in the malaria fight, and the only way we’re going to succeed is through relentless innovation. We need the next generation of tools and new implementation approaches; we need to harness the power of distinctly modern advances such as the use of mobile phones and big data in heatlh.

Broadly speaking, we’ve identified five key challenges the world needs to solve to win this fight. Every two weeks, starting this Monday, we’ll zero in on one challenge and let you know who’s innovating to find solutions. The series will culminate in some big news regarding the malaria community’s plan to reach eradication, delivered by one of the world’s biggest names and most prolific innovators in fighting disease, Bill Gates.

So stay tuned, and join us here next week as we launch with Challenge #1: Find the Parasite!

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This is the introduction to our new series, Solve for M: 5 Key Challenges to Ending Malaria. You can find others here:

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Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/domenicos-ciao-to-malaria https://www.malarianomore.org/news/entry/domenicos-ciao-to-malaria

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

Domenico learned about our Power of One campaign through his employer, Novartis. Domenico works in the Vaccines and Diagnostics Division and is passionate about Africa. He leveraged his professional move from Italy to Switzerland to help fundraise for the campaign. At his family’s going-away party, Domenico shared stories from his travels to malaria-endemic regions in Asia and Africa, mainly Uganda, where he supports orphanages, educational institutions for disabled children, as well as projects for the economic independence of small communities. He hit a nerve and got the attention of his friends. Today, 56 have decided to support him and joined the campaign!

Domenico also hosted a garage sale to benefit the cause, which inspired shoppers to pay the full price, instead of haggling for a better deal!

“This is a cause I really care about,” says Domenico. “I have increased my personal engagement significantly, and thanks to the support of my family and friend, we will be able to help 4,128 children with malaria”. Domenico found the campaign so rewarding, that he continues to fundraise for Power of One and to engage people around him. “One of my friends – a musician – after having donated called me in the middle of the night and told me he had just composed a song for my campaign. We are now discussing how we could use the song to help fight malaria.”

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2014--T:: https://www.malarianomore.org/news/entry/eating-pizza-with-katharine-mcphee https://www.malarianomore.org/news/entry/eating-pizza-with-katharine-mcphee

Malaria No More ambassador Katharine McPhee is fighting for good on TV and in her real life. Having traveled with us to Ghana and Burkina Faso in 2012 and having supported our most recent campaign called the Power of One (Po1), Katharine had a lot to talk about with a bunch of teenagers over pizza.

Academy Award-winning composer Hans Zimmer launched a web series called Pizza with an Icon, where teens can ask questions of influencers and all the good work they’re doing. In this segment, Katharine talks about her travels and how everyone can do their part to help end malaria deaths.

"It's such a tragedy that there are people dying from something that is so easy to cure," Katharine said. "It’s important for people to know that it’s not that hard to make a dent in a small part of the world that you may not necessarily even have any connection with.”

We couldn’t be more grateful to Katharine and all her hard work on the cause.

“Katharine has been an incredible supporter of Malaria No More for years, she is truly engaged in the push to eliminate deaths from malaria,” said our CEO, Martin Edlund. “Using her platform to raise awareness for the Power of One test and treatment campaign partnered with Novartis and Alere, Katharine has made a huge impact helping us move toward achieving our goal of raising three million treatments in our first partner country, Zambia.”

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2014--T:: https://www.malarianomore.org/news/entry/support-spotlight-roger-waltzman https://www.malarianomore.org/news/entry/support-spotlight-roger-waltzman

On World Malaria Day, our partner Novartis kicked off an employee engagement effort encouraging their employees to get behind the malaria fight. From April 25th, to our Independence Day, July 4th, Novartis employees got active and joined the fight through Power of One.

Roger Waltzman, in charge of developing new antimalarials at Novartis, is one of the top contributors to this employee engagement effort, having raised over 18,000 USD towards treatments for kids in Africa. Here, he’s filled us in on his work and how he raised all that money.

Q. Why do you believe in fighting malaria, and how did this contribute to your decision to start a fundraiser?

A. I believe it’s crucial to make available high quality medical treatments for people all over the world, particularly for those vulnerable people who are at risk for preventable, curable diseases. The focus of my work at Novartis is developing new antimalarials and I wanted to generate more attention both within and outside my work environment about the importance of this effort.

Q. Did anything interesting happen while you were fundraising? Did any of your supporters do or say anything really encouraging?

A. Quite a few people didn’t know that developing new antimalarials is the focus of my work and they seemed happy to hear this and happy to contribute. I appreciated their comments; one person simply said, “Good work should be supported,” and I thought that was so matter-of-fact and genuine. Some people contributed $1, since you could contribute any amount, and others contributed much more!

Q. How has this program increased your charitable efforts this year, compared to an average year?

A. I made a personal commitment to contribute to the campaign 10% of however much money I could raise from others. That ended up being one of my largest charitable contributions this year and I was delighted to do it.

Q. Now that the employee engagement campaign is over, how will you continue your efforts to help end malaria?

A. My daily work is focused on the development of better treatment or prevention of malaria, so the biggest change is that I feel even more determined and inspired by seeing the very positive response this campaign engendered in friends and family.

Q. Is there anything else you would like to tell us about your experience with our Power of One, Malaria No More, or the Novartis employee engagement campaign?

A. I was delighted that MNM created a campaign that was so simple, with a personal link for tracking contributions, and by enabling donors to contribute as little as $1. I felt completely comfortable asking my friends, family, and colleagues to consider donating something, anything, since the amount did not need to be large. I usually don’t find fundraising a particularly comfortable activity, but this enabled me to feel very comfortable with the “ask.” I am delighted that Novartis and MNM are collaborating in this and other ways. Eradicating malaria will take a huge effort on the part of many people and we need to collaborate for the benefit of the hundreds of millions of people who are infected every year.

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Malaria Treatments, Novartis, Supporter Spotlight, 2014--T:: https://www.malarianomore.org/news/entry/the-worlds-deadliest-animal-gets-airtime https://www.malarianomore.org/news/entry/the-worlds-deadliest-animal-gets-airtime

This past World Mosquito Day we were on ABC 7’s Let’s Talk Live discussing what else but mosquitoes, the deadliest animals on the planet.

Malaria Policy Center staff Josh Blumenfeld and Hannah Bowen, as well as our partner from DC Mosquito Squad, Damien Sanchez, spoke to the threat of malaria on Wednesday’s show. Watch the full show below.

Watch the video here: http://www.wjla.com/blogs/lets-talk-live/2014/08/world-mosqutio-day-22781.html 

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2014--T:: https://www.malarianomore.org/news/entry/young-cameroonian-comic-joins-the-malaria-fight https://www.malarianomore.org/news/entry/young-cameroonian-comic-joins-the-malaria-fight

Arnold Mbolo, a high school senior from a family of six kids, joined the Junior Ambassador program in April 2014 after placing 6th with a comedic sketch in the MNM Cameroon school contest. When asked why he participated, he responded “I like challenges. I’m a competitive person. But, I realized that the contest educated me. Before, I barely knew anything about malaria, hence I have also won in knowledge.”

For Arnold, humor is something he’s been around all his life - with a professional comedian as an uncle, helping him to develop into a charismatic comedian who is responsible for “cultural animation” in his local youth association, MOJAM. In just four months, Arnold has emerged as an all-star Junior Ambassador, using his energy and comedic talents in various events at school and with MNM to ensure his community is invested in putting an end to malaria.

The goal of the Junior Ambassador Program is to engage youth leaders from high schools across Yaounde, Cameroon’s capital city, to target their peers and wider communities through interpersonal communications, including clubs, school events and other activities. Arnold has done just that. He mobilized the other Junior Ambassadors to organize a school fair at his high school, where they had a stand teaching students about malaria prevention, which was also visited by the Secretary to the Minister of Education who encouraged the Junior Ambassadors to keep doing great work. He was selected as the K.O PALU mosquito mascot for the World Malaria Day Caravan and performed his winning sketch at stops throughout the city. Arnold has also received permission from his school to post K.O. PALU educational posters and a malaria prevention mural, ensuring malaria education and awareness are a part of everyday activities at school.

For World Mosquito Day 2014, Arnold worked with a fellow Junior Ambassador to mobilize hundreds of youth and community members, the mayor, and local chief to clean up a neighborhood to get rid of its standing water – which can be mosquito breeding grounds, especially during the rainy season.

Arnold is truly leading the charge, setting an example for fellow Junior Ambassadors and his community and motivating them to join the fight against malaria.

Stay tuned for more on the amazing work our Junior Ambassadors are doing in Cameroon to ensure their communities understand the threat of malaria and know how to protect themselves against the disease.

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Cameroon, 2014--T:: https://www.malarianomore.org/news/entry/world-mosquito-day-america-africa https://www.malarianomore.org/news/entry/world-mosquito-day-america-africa

On World Mosquito Day, spoiling a BBQ is a mosquito’s most minor offense

My daughter Nell is just 8-months old, so this is her first summer. Her first taste of freshly yanked grass from the yard. Her first sunburn.

She and her big sister, 4-year-old Maret get to stay up way past their bedtimes, as we soak up what remains of the humid evenings and the lingering sunlight. And of course there’s the uninvited guest at outdoor summer events - the mosquito, that tiny but persistent blight on our backyard barbecues and pool parties.

This week at Malaria No More, we stop to acknowledge World Mosquito Day August 20th. Devoting an entire day to the mosquito may seem like overkill, until you remember that the mosquito is, in fact, the world’s deadliest living creature. This day in particular was chosen because it marks the anniversary of British surgeon Dr. Ronald Ross discovering that mosquitoes carried malaria back in 1897 – a breakthrough that set us on the path to ending this disease.

"A mosquito bite in the states only means a few days of minor irritation, rather than contracting a life-threatening disease."

As I dab the calamine lotion on the red bumps that dot Maret’s skin, I get a flash of the anxiety parents must feel in Africa, where mosquitoes lead to the deaths of more than a thousand children every day.

I remember El Hadj Diop, the Senegalese father who dedicated his life to ending deaths from malaria in his home community after losing his 11-year-old daughter, Ami, to the disease. I’m haunted by the face of the nameless Nigerian dad I encountered as he arrived, desperate, at a clinic with his daughter on the verge of a malaria coma. Pictures of both fathers hang above my desk.



Above:  El Hadj holds up a picture of his deceased daughter; a Nigerian father holds his malaria stricken daughter

These are but two examples of the African parents who lose their precious children to a mosquito bite every minute of every day. And my eyes well up at the prospect of that happening to Nell or Maret. We’re lucky here in the U.S., where malaria was eradicated in 1951. A mosquito bite in the states only means a few days of minor irritation, rather than contracting a life-threatening disease.

The good news is that we can help protect children who still live with the reality of a potentially deadly mosquito bite. Just one dollar buys and delivers a life-saving test and treatment for a child in Africa through our Power of One campaign, thanks to our partnership with Alere and Novartis.

So this World Mosquito Day, please consider contributing. With your help, we’re closer than ever to mosquitoes becoming just another summer nuisance alongside sunburns and brain freezes, instead of the world’s most deadly predator.

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2014--T:: https://www.malarianomore.org/news/entry/u.s.-senate-staff-see-government-malaria-investments-overseas https://www.malarianomore.org/news/entry/u.s.-senate-staff-see-government-malaria-investments-overseas

For many Americans, it’s difficult to see the impact foreign aid has on people half a world away. We’re working hard to close that gap, and bring stories from malaria endemic countries home. That’s why, last week, we brought three Senate staffers to Dakar, Senegal and Geneva, Switzerland; where the staff learned firsthand the impact malaria has across all aspects of the Senegalese health system. They also experienced the inspiring progress that Senegal has made with the help of partners like the U.S. President’s Malaria Initiative (PMI) and the Global Fund to Fight HIV/AIDS, TB, and Malaria, to which the U.S. is the largest donor.

Day 1

The week kicked off in Dakar with meetings at the U.S. Embassy and Senegal’s National Malaria Control Program, where staffers heard from the program officers on the ground working to eliminate malaria about challenges and successes in the region. We learned how malaria fits within a broader health and economic context in the region, and why so many parts of the Senegalese government, private sector leaders, and development partners are committed to fighting malaria. The PMI Resident Advisor helped to guide us around and explain how PMI’s staff from USAID and the CDC support Senegal’s health system.

Day 2

Tuesday started bright and early with a short drive to the Peace Corps Headquarters in Ngor where the team was briefed by Country Director Cheryl Gregory Faye and Vanessa Dickey, Director of Programming & Training, then boarded a van for the almost two-hour drive to Thies, where we saw the great work Peace Corps volunteers are doing to combat malaria as part of their continent-wide “Stomp Out Malaria in Africa” program. We even Skyped with volunteers from other countries who are implementing the same community-based case management strategies that were developed in Senegal and which are now in Benin, Madagascar, and other countries. Over a lunch of delicious family-style Senegalese yassa chicken, we heard presentations from current Peace Corps volunteers about some of the major challenges they face in the area, including commodity stock outs, village access and communication. We learned what they are doing in partnership with PMI to overcome these obstacles and stomp out malaria.

 

Senegal Peace Corps & SLAP Lab

Above: Lunch with the Peace Corps; visit to SLAP lab

In the afternoon we were able to see cutting-edge research taking place at the Parasite Control Service. Dr. Sy and Dr. Ndiaye presented the monitoring and research activities which are supported by various US governmental and higher education institutions including the NIH, CDC, USAID, Peace Corps as well as Tulane and Harvard Universities. The lab, although subject to challenges like fluctuating electricity (our demonstration of the microscopy center was cut short by a power outage), is helping track insecticide resistance and studying the genetic markers of parasites to track parasite populations over time. The day ended with two site visits, one to a larger health center in Thies and another smaller health hut in Keur Madaro, where we had the opportunity to meet the community leaders and health workers.

Day 3

On Wednesday, the team headed out to see another key global malaria partner, PATH. The PATH country director explained PATH’s work to strengthen the health system in Senegal through community empowerment and malaria prevention and treatment. After a brief visit and presentation from young members of the Malaria No More Club in a nearby school, the staff headed to a lunch, hosted by MNM’s long-time partner, Senegalese NGO Speak Up Africa, with key business leaders to hear why they care about malaria and what they are doing to stop malaria from draining Senegal’s economy. The ideas proposed by bankers, builders, and leaders of other industries included issuing a malaria bond, setting up a health investment fund, and contributing in-kind expertise and materials to the fight – something several leaders in the room pledged to do.

We made a quick stop to see a warehouse where the Long Lasting Insecticidal Nets procured with PMI funding are housed before being distributed nationwide, then arrived to our last meeting in Dakar with the Minister of Health, Dr. Awa Marie Coll-Seck. Given her previous experience as Roll Back Malaria’s Executive Director, the Honorable Awa Marie Coll-Seck’s vast knowledge of malaria allowed our time to be more of a working session than a typical courtesy call. During the hour she spent with the team, the Senate staffers were able to report back what they found from their time in Dakar, including the challenges of supply chain management to rural areas, but also the successes of the partnership between PMI and the inspiring staff of the National Malaria Control Program.

 

Senegal LLIN & Minister of Health

Above: Visit to the LLIN warehouse; meeting with the Minister of Health

The Minister of Health also spoke about Senegal’s commitment to pre-elimination and its challenges and strategies for tackling the higher-burden southeastern regions, such as indoor residual spraying and seasonal chemo-prevention for children. She also stressed the need for private sector engagement, and shared that she was very pleased to have presented Senegal’s story at the official health event during the trade and investment themed U.S. Africa Leaders Summit in Washington, D.C. the week before.

Geneva

After an overnight flight to Geneva, the team ended the trip with debriefing meetings to link the lessons from Senegal with broader global strategies for malaria and innovation for the next wave of the fight.

Experts from the Global Fund, the WHO’s Global Malaria Programme, Medicines for Malaria Venture, and MNM’s Power of One partner Novartis all shared their perspectives on the global fight against malaria, answered the staff’s questions in great detail, and closed out a busy, but productive, week.

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Advocacy, Senegal, 2014--T:: https://www.malarianomore.org/news/entry/how-ebola-makes-malaria-more-deadly https://www.malarianomore.org/news/entry/how-ebola-makes-malaria-more-deadly

If you’re even a casual consumer of news, you’ve likely heard plenty about New York City resident Eric Silverman, who was hospitalized recently at Mt. Sinai hospital after displaying symptoms of Ebola.

While the media went into overdrive, it turns out that the Brooklyn man – who recently returned from Sierra Leone – was likely suffering from malaria. The mistake is understandable, since the two diseases display similar symptoms - such as fever, headache, and aching joints. As The Gothamist headline joked, “Ebola Man" Probably Just Had Boring Malaria.

The Ebola fears are well justified: As the death toll in West Africa surpassed 1,000, the World Health Organization recently approved the experimental use of drugs to try to save infected patients. But the reality is that “boring” malaria kills more people every day - about 1,700 - than have died in the Ebola outbreak to date. And, with the rainy season underway in West Africa, the Ebola outbreak may compound malaria’s deadly effects. As Bloomberg reports, Sierra Leone residents suffering from malaria are staying away from health clinics and hospitals, fearing they may be quarantined or infected with Ebola from a sick patient.

Unlike Ebola, we have simple cost-effective treatments for malaria. They key is getting them in time, since kids can die within the first 24 hours of the onset of malaria symptoms.

So, as health officials tackle the Ebola crisis, they must take special pains to encourage people to seek timely testing and treatment for similar-seeming illnesses, so “boring” malaria doesn’t become even more deadly.

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2014--T:: https://www.malarianomore.org/news/entry/asia-the-next-frontier-in-the-malaria-fight https://www.malarianomore.org/news/entry/asia-the-next-frontier-in-the-malaria-fight

MNM staff just returned from Singapore, where we held an official event to kick-off our partnership to fight malaria with the Asia Pacific Leaders Malaria Alliance (APLMA) and the Asian Development Bank (ADB). 

The Asia-Pacific region is home to more than two billion people at risk of malaria infection and accounts for 32 million cases of malaria each year. Recently, resistance to the front line treatment to the disease, aretemisin-based combination therapies (ACTs), has emerged in the Greater Mekong Region. This is a major concern to the public health community, as ACTs are the most effective way to treat malaria, and past resistance to malaria treatment has spread from Asia to Africa, where most cases of the disease occur.

The reception celebrating the new collaboration took place at the St. Regis Hotel in Singapore with attendance from both private sector and government leaders including Alere, the American Chamber of Commerce, Bayer, Chevron, ExxonMobil, Edelman, Kimberly-Clark, and US Embassy and Australian officials.

While many of the business leaders in the room understand the importance of defeating malaria in the region, the goal of the event was also to take advantage of their expertise and resources to leverage engagement across additional sectors.  To that end, MNM staff heard directly from the private sector representatives, including a presentation from Alere, about strategies to garner support within their organization as well as effective ways to engage new champions in the business world.

The event was a great start in helping to deepen the bench for the Champions of APLMA, which will be a major focus of the new partnership. The group will build a coalition of private sector leaders in Asia-Pacific to raise the profile of malaria as a massive roadblock to the region’s social and economic progress, and to advocate for the elimination of the disease in Asia and beyond.

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Advocacy, Asia, Malaria Policy, 2014--T:: https://www.malarianomore.org/news/entry/from-malaria-victim-to-malaria-victor https://www.malarianomore.org/news/entry/from-malaria-victim-to-malaria-victor

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

Today’s supporter, Chinweike, is what we at MNM call a super supporter. When his company, Novartis, encouraged him to take part in fundraising for our Power of One campaign, he set himself a lofty goal – to raise $1,500. Through Po1, that’s enough to provide malaria tests and treatments to 1,500 African children. And not only did Chinwe achieve his goal, he far surpassed it – raising $12,347! In fact, his personal fundraiser was so successful that he had to raise the bar for himself after just two days, as he had already met his initial $1,500 goal. For him it was more than just participating in a Novartis employee engagement effort. It was personal.

Growing up in Nigeria, Chinwe suffered from malaria during his childhood, as did many of his family members. Chinwe, who is now working at the Novartis Institutes for BioMedical Research, beat tough odds. While major progress has been made since he was a child in Nigeria, malaria still takes a massive toll on the world’s children - with a child dying every minute from the treatable disease.

Though he left the country as a teenager, he says his ties to the continent still remain. He has taken part in African medical and education programs since leaving, and was especially drawn to the scale and ambition of the Power of One effort, which has already raised enough money to provide malaria treatments to two million children. “A death a minute for a preventable and treatable disease is just unacceptable,” says Chinwe. “To be able to change a life with a dollar is quite a bargain.”

Chinwe’s passion for Po1 was contagious. Though he had just started in his position, he used the campaign as a way to connect with new co-workers. He took the message everywhere he went – from work, to the airport, to his monthly poker game – he even fundraised at a couple’s engagement party! And his family is just as excited about the cause as he is. His 10-year-old son and 8-year-old daughter offered up their savings to be donated. His wife sent messages to her friends and family soliciting donations, and made sure Chinwe was actively fundraising through some good-natured spousal nagging.

And the impact was incredible – as Chinwe says he’d never given or raised even a third of what he did through Power of One. And he plans to continue raising money for the campaign throughout the year.

While Chinwe provided enough money to test and treat more than 12,000 children for malaria, he says he benefited from the effort as well. “It was a great thrill doing this,” he says. “I have reconnected with a host of great friends and colleagues from my pre-Novartis days, and in less than six months at the company I already know I have wonderful colleagues and friends I can count on.”

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Malaria Tests, Malaria Treatments, Novartis, Power of One, 2014--T:: https://www.malarianomore.org/news/entry/20750-nets-for-pregnant-women-and-children https://www.malarianomore.org/news/entry/20750-nets-for-pregnant-women-and-children

Thanks to MNM’s generous international donors, MNM Cameroon was able to purchase 20,750 long lasting insecticide treated mosquito nets (LLINs).

The majority of the nets will go to the two populations who need it the most: pregnant women and children. Malaria attacks these two groups the most viciously, where 45% of malaria deaths are children under 5, and pregnant women suffer from miscarriages and birth complications.

The nets will also be used as prizes for community sensitization activities and radio contests to engage the public and test their malaria knowledge.

MNM Cameroon donated 15,000 LLINs to the Ministry of Public Health to be distributed to pregnant women during their antenatal visits in health centers in the Center region, where net possession is the lowest. When a pregnant woman goes in for her prenatal care, she will receive this three-year-lasting net, and as of her fourth month of pregnancy the health centers also provide her with free Intermittent Preventative Treatment (IPT), which protects her and her baby from malaria.

In Cameroon a child is lost every four hours to this killer. Mosquito nets are still the most efficient protection against malaria, but unfortunately orphanages are not covered by the universal net distributions.

Because of this - and in honor of the International Day of the African Child in June - MNM Cameroon went to four different children’s centers to teach 160 orphans, abandoned and disadvantaged children and caregivers about malaria. K.O. PALU Junior and Senior Ambassadors donated food to the orphanages, performing malaria themed songs and leading an interactive quiz with exciting prizes. After the sensitization session, nets were installed on each of their beds.

In Yaoundé, MNM was invited to join in on Day of the African Child celebrations at two centers in collaboration with “Association des Jeunes pour un Comportement Positif” (AJECP- an association founded and led by a former MNM intern) and “Hope for All.”

At one of the centers in Yaoundé, K.O. PALU Ambassador and Percussionist Zorobabel performed with his cute and talented sons for the first time. After his performance, the children performed a creative malaria-themed sketch, which included using headphones for a stethoscope.

In the Southwest, Peace Corps Volunteers stationed there came out to help, as did K.O. PALU Ambassador and singer Sine and Radio Balafon’s Cyrille Bojicko.

To increase the chances of the nets being used, MNM aired them out in advance and directly installed the nets after the sensitizations. With the help of the ambassadors, the team also put up posters in each center that encourage mosquito net usage.

After the installation of nets, every child received a bracelet and sticker to encourage them to sleep under their bed nets nightly in order to be healthy and fulfill their dreams.

Caregivers and the center’s directors testified about the malaria cases they have endured, including one 8-month-old baby who died from malaria. They expressed their gratitude toward COTCO-ExxonMobil for the net donation, promising to ensure the children use and maintain the nets regularly and appropriately. They all believe they will now suffer fewer cases of malaria thanks to these nets!

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Cameroon, Mosquito Nets, 2014--T:: https://www.malarianomore.org/news/entry/70000-children-treated-through-venmo1 https://www.malarianomore.org/news/entry/70000-children-treated-through-venmo1

Your friend just paid you to split a cab ride, and you just purchased a malaria treatment for a child in Africa. It’s that easy! Through mobile payments provider Venmo, people all over America have been donating to our Power of One platform as part of their everyday lives.

When we launched Power of One, we wanted to make it so effortless to treat a child for malaria that you could do it while going about your daily business. When we met Venmo, a mobile app that lets you easily pay your friends back for a beer or concert ticket and socialize it in your newsfeed, we not only realized that this was attainable, but that the platform’s socially engaged user base could create a massive impact.

As of today, Venmo donors have provided a whopping 70,000 malaria treatments to children in Zambia, a total of $35,000 in one-dollar treatments, which was matched with 35,000 treatments provided by our Power of One partner, Novartis.

Users were able to donate with just one tap on their phone while cashing out their Venmo balance to their bank account. Even cooler, they could donate through their newsfeed! Any time a payment was made to Malaria No More, the payment would appear in their friends’s newsfeed, along with a hyperlink to create a one-touch donation of their own. The result was a viral loop of donations, and Venmo users had tons of fun with all of the social features that came with it (see below).

We’d like to extend a huge thank you to Venmo for their innovative efforts to end malaria deaths, and to our treatment partner Novartis for matching the impact that was made. Through the help of our partners and supporters, we’re one step closer to finally making malaria no more!



Venmo users having fun while treating kids for malaria

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Mobile and Malaria, 2014--T::

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Malaria No More NewsMother�™s First Fundraiser a Big HitOutbreak Responder: A different game for a different future.Q&A with Ray Chambers, Challenge #5: Fuel the FightThis Baby Accepts Credit CardsThe shrinking malaria mapBill Gates: We can eradicate malaria in our lifetimesChallenge #5: Fuel the FightChallenge 4: Data & MobileChallenge #4: Data & Mobile �“ Ashifi Gogo, CEO of SproxilChallenge 3: Block TransmissionChallenge #3: Block Transmission - Grey Frandsen, Kite PatchThis mosquito helps save lives from malariaChallenge #2: Complete Cure �“ Roger Waltzman, NovartisChallenge #2: Complete CureDeconstructing malaria with Femi KutiChallenge #1: Find the Parasite - Duncan Blair, AlereChallenge #1: Find the parasiteSolve For M: 5 Key Challenges to Ending MalariaDomenico�™s �œCiao” to malariaEating Pizza with Katharine McPheeFrom behind the scenes to the spotlightThe World�™s Deadliest Animal Gets AirtimeYoung Cameroonian comic joins the malaria fightIt�™s Summer Time, and the Life-Saving is EasyU.S. Senate Staff see malaria investments overseasHow Ebola Makes Malaria More DeadlyAsia: The next frontier in the malaria fightFrom malaria victim to malaria victor20,750 nets for pregnant women and children70,000 children treated through Venmo!

ntent-Type: text/xml; charset=utf-8 https://www.malarianomore.org/ en Copyright 2014 2014-11-20T22:38:00+00:00 https://www.malarianomore.org/news/entry/mothers-first-fundraiser-a-big-hit https://www.malarianomore.org/news/entry/mothers-first-fundraiser-a-big-hit

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

Being a mother of three children, Inge was touched by our Power of One campaign’s simplistic message – $1 given = 1 child saved – and decided to start her fundraiser. She learned about the campaign through her employer, Novartis, a company that has been committed to the fight against malaria for more than a decade.

Her boss at Novartis was the initial inspiration to get involved – and was one of her biggest supporters. “She was the first to donate a large amount of money to kick start the fundraiser,” said Inge. “And she also reached out to her personal network that resulted in donations adding up to several thousands of dollars.” Inge also shared stories with other co-workers who were also fundraising for the malaria fight.

Inge says the Power of One message made her first fundraising effort an easy one. “I just had to reach out to my family, friends and colleagues via email – and the results were amazing!” said Inge.

Inge’s campaign was so successful that she kept moving her fundraising goal up! “Two days after launching my fundraiser I had to increase the target,” said Inge. “One week before the end of the campaign, I was at 4400 treatments, so I raised the target again. I am proud that together, in the end we could raise more than 5600 treatments.”

While this was Inge’s first fundraising campaign ever, it doesn’t seem like it will be her last. “Personally it has been a very rewarding exercise,” said Inge. “I have been very blessed in many aspects and the campaign has given me the opportunity to ‘give back’ and feel the joy and pride in encouraging others doing the same.”

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Power of One, Supporter Spotlight, 2014--T:: https://www.malarianomore.org/news/entry/outbreak-responder-a-different-game-for-a-different-future https://www.malarianomore.org/news/entry/outbreak-responder-a-different-game-for-a-different-future

MNM is always looking for new and interesting ways to bring attention to the malaria fight. That’s why we’re really excited to partner with Global Gaming Initiative on its latest endeavor, which will benefit Malaria No More’s Power of One campaign.

When we started Global Gaming Initiative, (GGI) we wanted to utilize technology for good by creating a fun and easy way for people to make a difference. Our solution - mobile games. The goal being to inspire the developed world to get involved globally and provide the developing word greater access to education.  This year we ourselves received a massive education in the realities of global health issues, specifically malaria. The reality that malaria is a completely treatable disease, which an estimated 627,000 still die from annually, was both beyond unsettling and urgently motivating. We partnered with developers who share our desire to create a future without malaria to create our combative agent, Outbreak Responder, as we know that nothing is possible without health.

Outbreak Responder - using beautiful graphics and strategic challenges puts the player on a mission to cure communities from the spread of malaria. The best part is, being an Outbreak Responder player, you literally become an agent of change as your in-game contributions unlock malaria tests and treatments for African children through Malaria No More’s Power of One campaign. We have long admired the work Malaria No More does on the ground and are thrilled to partner with them to help you provide a healthy future for children with malaria. This is what fun and games and saving lives looks like. It’s the power of the change in your pocket – so download Outbreak Responder, put your game time to good use and help us create a better future, one child at a time.

Learn more about Outbreak Responder here.

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Mobile and Malaria, 2014--T:: https://www.malarianomore.org/news/entry/qa-with-ray-chambers-challenge-5-fuel-the-fight https://www.malarianomore.org/news/entry/qa-with-ray-chambers-challenge-5-fuel-the-fight

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge #5 focuses on a crucial component of finally ending malaria – maintaining and growing funding. For more, we spoke to Ray Chambers, co-founder of Malaria No More and United Nations Special Envoy for Financing the Health Millennium Development Goals and for Malaria.

1. What are some of the changes you anticipate in global financing for health over the next decade?

Funding has increased dramatically for global health since the world got serious about saving millions of children and mothers from preventable causes. The results have been impressive: Since 2000 the number of under-five deaths worldwide has declined from 12.7 million in 1990 to 6.3 million in 2013. But continuing to fund these gains from donor countries is not sustainable, especially if we want to move toward the elimination of malaria. We need to support three existing trends that can shift us to a new funding paradigm.

Endemic countries must increase their domestic health budgets. Domestic financing for malaria increased over the period of 2005 to 2012, from $436 million in 2005 to $522 million in 2012, rising at an estimated rate of 4% per year - a move in the right direction. But most countries still fall short of the Abuja target of dedicating 15% of their domestic budgets to improving health.

We must approach financing of life-saving commodities more creatively. We’re seeing early success from pay-for-performance social impact bonds that demonstrate the returns on investing in net distribution in Mozambique. An innovative tax on airline tickets to support work on AIDS, TB and Malaria has produced millions of dollars for AIDS treatment.

The private sector has recognized that healthier communities are better places to do business, and investing in the health of employees in the countries where they operate can help the bottom line as well.

2. How important have the Millennium Development Goals been to galvanizing support for malaria and other global health programs?

As a businessman I was drawn to the MDGs as time-bound, quantifiable targets against which we could measure our success. The inclusion of malaria in Goal 6 of the MDGs was essential to allowing the global health community to rally around the malaria targets. With this support came coordinated plans and, crucially, financing to enact those plans. Similarly with child and maternal health, by quantifying where we were, and where we needed to get, the MDGs provided the outline of a roadmap others could build upon and collectively enact. And with all 193 countries signing on to the MDGs back in 2000, their value has gone well beyond the tangible achievements of lives saved. They’ve linked all of us in a shared pursuit of something greater than our individual or even national selves. This shared global consciousness will carry the spirit and ambitions of the MDGs well beyond 2015.

3. How do you expect the funding landscape to change at the end of 2015, when the Millennium Development Goals deadline hits?

Relying on outdated models of north-to-south donor contributions will eventually hit a wall, and some would argue that the fatigue has already begun to set in. If we continue to think creatively about how we finance life-saving programs and commodities among a broader community - leveraging previously untapped resources, especially from the private sector - funding for health should continue to grow. Companies including Exxon Mobil, Chevron, Unilever and AngloGold Ashanti have demonstrated the leadership role businesses can play in keeping populations healthy. Similarly, the private sector plays an essential role in the research and development of new technologies and vaccines that could replace existing costly interventions. Now is the time to test new models of funding while investing in research that could deliver cheaper, more effective diagnostics, treatments, and vaccines.

4. What would the consequences be if malaria funding were scaled back?

Recent history has already demonstrated what happens when funding for malaria is decreased or held-up. From 2006 t0 2008 net coverage dropped due to delayed funding disbursements, resulting in an upsurge of malaria cases in 2009.  We’ve successfully covered almost every person in need of a net with a net, and in doing so saved over 3.3 million children since 2000. But as a result of this success, millions of children protected by nets have no immunity to malaria. If their nets aren’t replaced every three years, we will see malaria infections and deaths far exceed previous levels. Total funding for malaria control is expected to reach $2.85 billion each year between 2014 and 2016, substantially below the required amount for this period. We have come so close to lifting the burden of malaria off an entire continent. A final push - in political commitment, partner support and funding - will put the end of malaria deaths in our grasp and make elimination a reality.

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5 challenges to end malaria, Advocacy, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/this-baby-accepts-credit-cards https://www.malarianomore.org/news/entry/this-baby-accepts-credit-cards

Above:  Manishha Patel used inventive and fun memes to rally her friends to donate to Power of One.

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

MNM supporter Manishha raised money for our Power of One campaign with the help of her good-hearted loved ones and colleagues at her employer, the Genomics Institute of the Novartis Research Foundation (GNF). Fundraising for the cause came naturally to her given the lessons her parents taught her growing up – to be appreciative of the opportunities she has and to help those less fortunate.

“My parents are from a very rural and poor region of India,” says Manishha. “They always taught us to be grateful for the opportunities that were given to us in Canada and to help and care for the less fortunate.”

 



Manishha has always felt a strong urge to help those less fortunate. “I have always wanted to help people in underdeveloped countries, and Power of One affected me because of the impact it can have for people in Africa – the idea that just one dollar can save one person’s life really resonated with me and I wanted to help them in any way that I could.”

In addition to drawing on the wise words of her parents, she drew on the talents of her boyfriend. Together, they came up with eye-catching posters, featuring funny pictures of babies offering words of encouragement. And the kid theme didn’t end there – Manishha even inspired her niece and godchildren to donate their piggybank savings.

Manishha’s colleagues were a huge help too. They championed her cause to their families, friends, religious organizations, and sports teams, helping her break her past fundraising record of $500! “The sheer amount of support from GNF as a whole was phenomenal,” said Manisha. “The encouragement and support I received for the campaign was unbelievable, and helped me eventually recruit more than 330 friends to join Power of One.”

Good news is Manishha isn’t done yet. “This is the kind of work I have dreamed of doing and that is why I decided to get involved in the fundraiser,” said Manishha. “I will continue to promote the cause of Malaria No More and I hope that, in the very near future, malaria will no longer be as devastating a disease as it is now.”

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2014--T:: https://www.malarianomore.org/news/entry/shrinking-malaria-map-bill-gates https://www.malarianomore.org/news/entry/shrinking-malaria-map-bill-gates

This video of the shrinking malaria was shared by Bill Gates at the ASTMH conference.

Malaria has been killing for centuries. In 1900, it was taking lives from nearly every country on Earth, but the goal is to wipe this killer disease from the planet within a generation.

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2014--T:: https://www.malarianomore.org/news/entry/bill-gates-we-can-eradicate-malaria-in-our-lifetimes https://www.malarianomore.org/news/entry/bill-gates-we-can-eradicate-malaria-in-our-lifetimes

It was a packed house last night, as the best and brightest in the public health world poured into a New Orleans conference hall to hear one of the world’s most prolific philanthropists share his vision for the future of global health.

As Bill Gates joked, he was eager to finally have a captive audience for his thoughts on some of the world’s most pervasive diseases, as he typically bores dinner party guests with his excitement over discussing topics such as dengue fever, polio and malaria.

During his keynote speech at the Association of Tropical Medicine and Hygiene, Gates focused his remarks on Ebola and malaria. He spoke to the lessons the global health community can take from the Ebola crisis, and how it can serve to educate and strengthen our response to other public health issues. He spent the bulk of his speech talking about malaria, and urging the gathered group of the world’s premier scientists and doctors to embrace the idea of malaria eradication in our lifetimes. He also announced that the Bill & Melinda Gates Foundation will be increasing its already substantial financial commitment to fighting malaria by 30 percent.

Gates laid out the elements of a new strategy to achieve the ambitious goal of eradication, including fostering innovation in the surveillance and research & development arenas, as well as continued investment in malaria control efforts as we concurrently set our longer term vision on eradication.

You can read more on the new plan here. It is not an easy task, but with a shared vision and energy in the global health community, it is possible. His closing statement, which drew a standing ovation, echoed the sentiment that malaria eradication is within our grasp: “I’m optimistic we’ll get there faster than the skeptics think.”

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malaria elimination, 2014--T:: https://www.malarianomore.org/news/entry/challenge-5-fuel-the-fight https://www.malarianomore.org/news/entry/challenge-5-fuel-the-fight

To win the malaria fight, we need to rethink how we pay for it

Malaria No More was founded by two prominent business leaders, Ray Chambers and Peter Chernin, who saw combating malaria as a unique opportunity to save lives and improve livelihoods on a global scale. As Chernin put it, ending malaria represents “the best humanitarian investment in the world today.”

It’s easy to see why. Malaria is a devastating disease and one of the top killers of children under the age of five and pregnant women worldwide. It’s also a huge drain on economies, accounting for approximately $12 billion in lost economic productivity in Africa each year, due to the burden it places on health systems and the toll of work absenteeism and missed school days.

By contrast, the existing tools are simple and scalable - a mosquito net can protect a mother and child for three years for around $5; a 50 cent rapid diagnostic test and $1 treatment can save a child’s life – and, as this series highlights, revolutionary new technologies are just around the corner.

When Malaria No More was founded in 2006, global spending on malaria was only a few hundred million dollars a year, and approximately a million people were dying from mosquito bites annually.

Through a massive global effort – including $3 billion in annual funding, led by the U.S. and U.K. governments, the Global Fund to Fight AIDS, Tuberculosis, and Malaria, the World Bank, the private sector and philanthropists - the rate of malaria deaths in Africa has been cut in half in under a decade. According to the World Health Organization, an estimated 3.3 million lives have been saved since the year 2000 from malaria alone.

 

Malaria funding now vs next

Planning for a Rainy Day

The danger with malaria - the thing that keeps us malaria fighters up at night - is that if you lose focus, even for a single rainy season, the disease can come roaring back with devastating consequences.

There have been 75 documented instances of malaria resurgence from the 1930s to the year 2000, and nearly all of them were associated with the weakening of malaria control efforts. If we stopped investing in malaria control today, it would cause a massive humanitarian crisis, claiming millions of lives, and undo the hard-fought gains we’ve made in the past decade.

As the burden of malaria continues to be reduced, we need to shift from catalytic “scale up” funding models to sustainable, long-term approaches that will enable us to end the disease. That means diversifying the sources of funding so that the continued commitment of international donors is buoyed by growing domestic and regional investments, as well as innovative financing approaches. It also means using better data to find efficiencies that will stretch and strengthen the impact of malaria spending at the country level.

Put Your Money Where Your Malaria Is

We often say that malaria is both a cause and a consequence of poverty. But the reverse is also true: malaria control is equally a cause and consequence of economic growth. It’s not just geography that caused malaria to be eliminated first in the United States in 1951 and most of Europe by 1975 - it was equally the result of economic growth, development and increased spending on health and infrastructure.

The current slate of countries moving toward malaria elimination – mostly in Asia and South America – are already covering the bulk of the expense themselves: almost 80 percent of interventions are self-financed, according to a recent analysis by UCSF’s Global Health Group and Cambridge Economic Policy Associates. 

 

Malaria funding vs deaths

In Africa, however, most countries still fall short of the self-declared “Abuja target” of dedicating 15% of domestic budgets to improving health. As “Africa Rising” moves from rhetoric to reality and economies on the continent continue to grow, Africa has the wherewithal to finance an increasing share of its malaria elimination ambitions. And it has powerful financial incentive to ensure the work continues - a recent study by Accenture estimated the present-day economic value (i.e. profit) of continued investment in malaria control in Africa at more than $322 billion between now and 2035, due to the tremendous health and productivity gains that would result.

Endemic countries also have the opportunity to stretch their budgets by working smarter. To the extent that countries can draw on good timely data to inform program decisions, they can save money by targeting the appropriate mix of interventions by region and setting. Zambia and Zimbabwe, for instance, have saved millions of dollars by using malaria risk-mapping to optimize their net and insecticide spraying programs.

Particularly as countries reduce their malaria burden, one-size-fits-all, national-scale approaches may no longer apply. Namibia, a country moving toward elimination, has used malaria and mobility data to develop a more sophisticated, spatially targeted malaria program.

The Future of Funding

Regional financing mechanisms are emerging for countries, companies, and philanthropists to invest in malaria control and elimination in their own backyards. Asia-Pacific has set the ambitious goals of eliminating drug-resistant malaria by 2020, and all malaria by 2030. To help finance the efforts, the Asian Development Bank and the Asia Pacific Leaders Malaria Alliance this year set up a regional trust fund to solve this pressing regional challenge.

Mechanisms for nontraditional donors to play a part in eliminating the disease are growing as well. In Indonesia, a small group of high net worth individuals have pledged to co-invest alongside the government and Global Fund in health priorities, while in the Philippines and Ghana companies with large local operations – the Pilipinas Shell Foundation and AngloGold Ashanti – have managed Global Fund malaria grants working hand-in-hand with government agencies.

Innovative financing efforts, including concepts such as development impact bonds, also have the potential to contribute. Creators of The Mozambique Malaria Performance bond aim to establish a sustainable new funding source that can also improve the efficiency of malaria programs through a pay-for-performance model.

It’s an attractive concept: private investors front the costs of malaria control interventions to be repaid by a group of government and private-sector partners who reap the rewards of successful malaria control, including healthy citizens, employees and consumers. But we have yet to see investors step up to participate in such an instrument vehicle. If these models take root, malaria could evolve from being “the best humanitarian investment” to an actual investment opportunity—one that pays a dividend to those who contribute.

Achieving the historic goal of malaria eradication requires endurance. To sustain and extend the gains of the past decade, the global community must commit to providing predictable, sustainable, long-term support.

Our success in fighting malaria over the past decade has been built upon a solid foundation of funding, and the continued support of the U.S., U.K. and Australian governments; as well as institutions such as the Global Fund and the World Bank, will be essential to finishing the job. But we also need endemic countries and regions to commit to shouldering an increasing share of the costs as we move toward malaria elimination.

In the end, it will not be one sector or government that will finally eradicate malaria. It will be a global success—one we should all be proud to have contributed to.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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5 challenges to end malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-4-data-mobile https://www.malarianomore.org/news/entry/challenge-4-data-mobile

How the mobile revolution in Africa is transforming global health

When I first moved to West Africa, back in 2009, you could travel to the most remote, rural villages – places without power, running water, or any other modern conveniences – and you would invariably find Coca-Cola. Somehow the familiar red-and-white brand had solved the distribution and marketing challenges of reaching these ends-of-the-earth consumers.

In those same remote villages, you can also find some of Africa’s highest-tech companies – mobile providers like MTN, Tigo, Airtel, Vodacom and Safaricom. Africa has leapfrogged the power line and the PC and gone directly to mobile phones. By the end of 2015, there will be an estimated 1 billion mobile phone accounts in Africa – one for nearly every man, woman and child on the continent.

First Disease Beaten By Mobile

In our first challenge (“Find the Parasite”), we talked about the importance of rapid diagnostics to locate the malaria parasite in people. What is a diagnostic test result but a plus or a minus, a one or a zero? It’s a bit of data. But in many malaria-endemic countries, that data used to just sit in stacks of paper to be collected every so often by health authorities. When you combine this data with rapid reporting via mobile phones, you have the makings of a revolution in global health.

Of all the tools in the malaria fight (including the obvious ones such as nets, testing, treatment and spraying) mobile phones may be the ones that tip the balance toward ending this disease. That’s why at Malaria No More we’ve been bold in proclaiming that malaria can be the first disease beaten by mobile.

A Swiss-Army Knife for Malaria

Sounds ambitious, but when you look at the problems we have to solve – from case detection and response, to stock management, and health education – mobile is at the center of the solutions time and again. It’s the Swiss Army knife of the malaria fight, helping to solve and accelerate a wide variety of other solutions. Here are a few examples of how mobile and data are already transforming the malaria fight.

The Novartis-led SMS for Life program has demonstrated the potential of mobile to address stock outs and ensure that people have malaria drugs when and where they need them. The pilot program focused on three districts in Tanzania. When it started, 26% of public health facilities were completely stocked out of malaria drugs at any given time. That means that parents had a one-in-four chance of showing up at a clinic with a sick child only to find that they didn’t have a dollar’s worth of life-saving treatment on hand.

To address the problem, under the umbrella of the Roll Back Malaria Partnership, Novartis and its public and private partners set up a simple, SMS reporting system that enabled health workers and pharmacists at public health facilities to record and report their stock levels on a weekly basis. This made it possible to anticipate shortages and distribute malaria drug supply more efficiently. Six months later, less than 1% of the facilities were stocked out of malaria drugs: a 97% reduction in stock outs through better and faster information flows. SMS for Life has now been expanded to several other African countries including Ghana, Kenya and Cameroon.

 

Mobile swiss army knife for malaria

In a similar fashion, mobile phones may be the key to solving the challenge of counterfeit and stolen malaria treatments. Nigeria is the epicenter of the malaria challenge, accounting for nearly a quarter of the world’s malaria burden. As the market for antimalarial treatments has grown, so too has the attraction for counterfeiters. Recent estimates suggest that nearly 40% of all antimalarials on the market are counterfeit.

The challenge is compounded by the fact that most Nigerians don’t get their treatments from public health facilities. Eighty percent of people go to the private sector for treatment. And this isn’t your corner Walgreens we’re talking about. In Nigeria, it’s not uncommon to see malaria drugs sold alongside open-air butcher stands and car parts in public markets.

The solution to this problem? You guessed it - mobile. Working with companies such as Sproxil, PharmaSecure and mPedigree, the Nigerian government now requires that every antimalarial drug (and antibiotic) carry a label that consumers can scratch off like a lottery ticket and text in for free to confirm their drug is authentic and safe. Read more about Sproxil’s efforts to combat counterfeiters here.

This scalable use of the technology is revolutionizing the fight against counterfeits, and even helping authorities to track down contraband drugs. Malaria No More is working with a group of partners to go a step further: to explore how this data – a real-time sample of antimalarial consumption – can be used to draw fresh insights that can inform public health decision-making to save even more lives.

The Big Benefits of Data

A study in Kenya presents another compelling example of leveraging non-health data to fight malaria.

Caroline Buckee of the Harvard School of Public Health worked with Kenya’s largest mobile operator to analyze anonymized mobile phone usage records from 15 million consumers to track human migration patterns. Researchers then combined this migration map with regional malaria incidence data to identify how malaria travels around the country via human carriers.

Unsurprisingly, most of the malaria emanated from the high-transmission areas along Lake Victoria on Kenya’s western border.  But the data also spotlighted unusually high migration from the Lake Zone region about 50 miles inland to the western highlands region.

A few clicks of a Google map reveal that the western highlands are host to massive and bustling tea plantations that serve as a kind of bus depot for malaria transmission. Infected workers came from the Lake Zone to the highlands, where mosquitoes picked up the parasite and infected fellow plantation workers, who in turn transported the parasite back to their home communities farther inland.

These data-driven insights can help direct resources and interventions to make the malaria fight more effective. For example, eliminating malaria in the Lake Zone might cut off the source of infections in the highlands – even if you didn’t run a large-scale elimination program in the highlands themselves.

Mobile Aids Elimination

If anything, harnessing the power of mobile and data becomes more important as countries move toward malaria elimination. As the scale of the problem shrinks, the need for timely and precise surveillance data only grows. Vital elements such as real-time reporting of cases and accurate intervention mapping are now possible thanks to web, mapping, mobile and data analytics tools.

As you move toward the end game of elimination, countries must be able to track and respond to every case immediately to prevent it from spreading. They set up a sort of SWAT-team approach (painful pun intended): rapid-response systems in which health workers immediately report cases and teams show up to test and treat people in a perimeter around the infection to contain the spread of the parasite.

Even more so than Coca-Cola, that gives us something to smile about.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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5 challenges to end malaria, Mobile and Malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-4-data-mobile-ashifi-gogo-ceo-of-sproxil https://www.malarianomore.org/news/entry/challenge-4-data-mobile-ashifi-gogo-ceo-of-sproxil

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge 4 (link to post) looks at ways technology and data can be used to fight malaria. Ashifi Gogo is the head of Sproxil, a company that uses mobile phone technology to combat dangerous counterfeit malaria medication.

1) Many people aren’t aware of the major threat counterfeit drugs pose, can you briefly describe the problem and how mobile authentication, such as Sproxil, helps fight it?

Drug counterfeiting, while particularly prevalent in emerging markets, is a global disease that threatens the safety and well-being of all citizens. 700,000 people die every year from fake anti-malarial and tuberculosis drugs alone: it is the equivalent of the entire population of Boston disappearing in a single year.

By leveraging the increasing popularity of mobile phones, we developed a simple, but powerful and secure SMS system: Mobile Product Authentication™ (MPA™). We partner directly with manufacturers and distributors to append security labels with a scratch-off panel on each product. At point of sale, a consumer will scratch off the panel to reveal a unique, single use code that they SMS to our phone number for free. The consumer instantly receives a response back confirming that the product is genuine or warning that it is suspicious. Our 24/7 help desk, which supports major local languages, is available for reports of counterfeiting activity and for questions relating to the product or solution.

To further reduce access barriers, we have multiple channels for verification: mobile apps (available on iPhone, Android, and Blackberry 7), web apps and our help desk.

2) You’re working to integrate Sproxil into more countries. Where do you provide service currently, and where do you plan to expand?

We have operations in Ghana, India, Kenya, Nigeria, and the U.S. and can execute projects on six major continents. In an effort to stay ahead of counterfeiters, we do not disclose our plans for expansion.

3) Beyond preventing counterfeits, do you see other ways to leverage this data to improve health?

Our technology was developed to be flexible and scalable. By creating direct communication channels between our clients and their patients, MPA can help foster healthier lifestyles. Our technology can support medical adherence programs, message patients with expiration reminders and health and wellness information or connect them with health care providers or other experts and even send special coupons or recommendations for other wellness products.  The opportunities for improving health by connecting patients with the appropriate resources make the possibilities limitless.

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5 challenges to end malaria, Mobile and Malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-3-block-transmission https://www.malarianomore.org/news/entry/challenge-3-block-transmission

The secret to ending malaria could be protecting mosquitoes from humans

As villains go, the mosquito is well cast. The tiny pest is unique in nature in two important respects. First, it has no redeeming value to the broader ecosystem (the name of the particular breed that transmits malaria, “Anopheles,” actually means “useless” in Greek); and second, the mosquito is by far the deadliest creature on the planet to human beings, claiming 725,000 lives a year—principally to malaria, but also to diseases including dengue fever and West Nile virus.

Even Disney, the company that made ants and lobsters lovable, has it in for the mosquito. In a now-famous 1943 animated short titled “the Winged Scourge,” a Disney narrator brands mosquitoes “public enemy number one” for transmitting malaria, and cheers as the Seven Dwarves gleefully pump insecticide and stomp the bug.

Our first two columns explored how finding the parasite(link) and completely curing(link) infected people are two of the keys to ending this disease. The missing piece is to block transmission and stop the endless shuttling of the parasite back and forth between man and mosquito.

You see, for malaria, the transit between mosquito and man isn’t just a joy ride—it’s an essential step in reproduction. By blocking transmission you isolate the mosquito and interrupt that process. In mosquitoes, the parasites die quickly due to their host’s short life spans; and the ones in humans stay contained until you can eliminate them with medication.

The classic approach to blocking transmission is to protect people from mosquito bites using bed nets or insecticide sprays. And make no mistake, these tools have been extraordinarily effective: a major factor in saving 3.3 million lives from the disease since 2000.

Rethinking the Problem

But to break the back of transmission, we have to rethink the problem. We must move beyond vilifying the mosquito—and the key may be protecting mosquitoes from humans.

Surprised? You shouldn’t be. Consider that mosquitoes only carry the malaria parasite for up to 30 days—a mosquito’s maximum lifespan—while humans can carry the parasite for decades if left untreated. And where mosquitoes can only travel a mile or two on their tiny wings, humans circle the globe transporting the parasite like carry-on luggage. So if we’re looking for someone to blame for malaria transmission, we must start by taking a hard look in the mirror.

The surest way to avoid getting malaria from mosquitoes is to stop giving it to them. That’s why a new generation of treatments that completely eliminate the malaria parasite from the human body will be so important (for more, read Challenge 2: Complete Cure). But it is only one of the novel approaches that will make it possible to stop transmission.

 



Next Generation Protection

Soon, the tried-and-true bed net may be joined by new vector-control technologies that use radar-jamming molecules to disguise humans from mosquitoes. That’s the goal of a technology called Kite Patch, which took the crowd-funding site Indiegogo by storm. Worn on your clothes, this small sticker is a spatial repellent that blocks a mosquito’s ability to register carbon dioxide. In effect, it acts like Harry Potter’s cloak of invisibility, making people virtually undetectable to mosquitoes. (Read more about the Kite Patch technology and what it could mean for malaria.)

This past summer, the pharmaceutical company GlaxoSmithKline registered for regulatory review of the first partially effective malaria vaccine—called RTS,S—and hopes for a WHO seal of approval as early as 2015. In clinical trials, the vaccine reduced the number of malaria episodes by a quarter in infants immunized and cut in half malaria cases in older children (toddlers) - low by vaccine standards, but unprecedented in terms of malaria.

But even as we celebrate this milestone – the first vaccine against a parasite – the focus of research is moving beyond only protecting individual people against malaria symptoms (as RTS,S does) to blocking transmission.

New vaccine approaches target two “choke points” when parasites are at their fewest in number during their complex life cycle: the transitions from mosquito to man, and from man to mosquito. These potential vaccines could effectively hold the line against onward transmission of the parasite, stopping malaria dead in its tracks.

Despite the PR campaign against mosquitoes, the goal of malaria control has never been to eradicate the insect, but only to control it as a way to get at our true adversary: the parasite. Little did we suspect that the key to eradicating malaria around the globe could involve making the mosquito an asset in the malaria fight.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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5 challenges to end malaria, Mosquito Nets, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-3-block-transmission-grey-frandsen-kite-patch https://www.malarianomore.org/news/entry/challenge-3-block-transmission-grey-frandsen-kite-patch

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge 3 addresses new technologies and approaches that are in development to block the transmission of the malaria parasite between humans and mosquitoes. To learn more about one such innovation, we spoke with Grey Frandsen from Kite Patch, a sticker that protects humans from mosquitoes by disrupting the insect’s ability to detect humans.

 

1. In our eco-conscious age, a lot of people are wary of putting chemicals on their skin to repel mosquitoes. But mosquito bites are an annoying problem in the U.S., and a deadly one in parts of the world such as Africa and Asia where the pests carry life-threatening diseases, including malaria and dengue fever. Can you tell us how Kite Patch works to protect from mosquitoes without using the traditional skin contact of insect repellents?

Kite Patch is a small, beautifully-designed little “sticker” that creates something akin to an invisibility cloak, or as some suggest, a defense shield, around our bodies with spatial compounds emitted from the materials on the sticker. This product form is being designed to emit a certain level of those spatial compounds over a period of time so that the compounds hover and swirl around the body with movement and wind, and travel away from our bodies in varying distances to intercept mosquitoes as they track toward us. Once mosquitoes come into contact with these compounds, they lose the ability to detect carbon dioxide and sense skin odors – the two primary mechanisms by which they track us.

We’ve designed Kite’s brand to capture the spirit of freedom and joy – something we believe will be the result of new technologies and products, such as Kite Patch, that will lift both the burden of disease and the burden of the fear of disease.

 

2. Kite Patch coming to fruition was a collaborative effort involving several different groups pitching in on funding. Can you tell us about the process of getting this innovation from the idea to the production stage, and where you’re at now?

Kite Patch absolutely is a story about collaboration. It’s also the result of a new model developed by ieCrowd to transform innovative discoveries into solutions to global challenges. This model brought together the innovative discovery, the capital, the development partners and experts, the team, and the range of stakeholders that now make up the large, global Kite campaign.

People may know the Kite Patch from our Indiegogo campaign. Last year we launched a crowdfunding effort to raise awareness and support for a specific field test of some of our Kite Patch prototypes. We wanted to expand the number of people involved in our development process and inspire people to play a role in getting a new technology to market.

The result was amazing. The campaign went viral and Indiegogo named it one of the top five campaigns ever. We enjoyed support from around the world. Over 500 publications ran original stories about our campaign, the technology, our process for commercializing this technology, and how we branded and marketed the campaign and the product itself.

As for the product itself, Kite technology stems from scientific findings initially discovered at the University of California, Riverside (UCR) with assistance from The Bill & Melinda Gates Foundation, and the National Institutes of Health (NIH). ieCrowd exclusively licensed the technology from UCR, and has, since then, furthered the science into a range of new technologies, in order to advance disruptive products such as Kite Patch. Kite products - ranging from new mosquito repellents to spatial attractants - feature spatial and non-spatial active ingredients.

The next major step is to get Kite Patch to the field, to markets, and into the hands of people who need it the most. To do so, we’ll continue to build partnerships around the world with those who share our passion for eliminating this horrible disease.

 

3. Some readers may think a sticker is a novelty item, but you see Kite Patch having major implications on the field of public health. Can you tell us how far-reaching you hope Kite Patch will be?

We want to be humble about the role Kite technology and products can play, but we do know this: while our mock-ups make it look cool and pretty (and don’t those kids in the below Kite Patch video look cute? Those are mine!), the Kite technology platform is being developed to support what we believe can be one of the most powerful weapons platform in the fight against mosquito-borne diseases. We have a world-class team working 24/7 to build a powerful platform of actives that can ideally be deployed around the world in a range of applications – all of which will have minimal impact on our health and the health of our environment.

 

WATCH: Kite Patch in Action

 

Specifically, we’re working on repellents and attractants that can be deployed in any number of product forms that will play important roles in public health and disease intervention efforts globally. We pay attention to every detail and we’re designing each of our products with history and current technologies and needs in mind. Most importantly, we have opened our development process to people around the world and continue to build our technology and products with significant inputs and feedback from the Kite crowd.

Our technical foundation is strong, and ieCrowd’s system for deploying disruptive new solutions like Kite Patch is ready for action. We’re excited about the prospects of the Kite platform, and with the help of the crowd, amazing partners, and the world’s best team, we have no doubt that it will be among the leading tools to fight against malaria and other mosquito-borne diseases.

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5 challenges to end malaria, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/best-fiends-malaria-no-more https://www.malarianomore.org/news/entry/best-fiends-malaria-no-more

While most of the world thinks of mosquitoes as blood sucking, disease-spreading pests, there’s a new guy in town who’s on a mission to redeem the rep of his fellow mosquitoes.  Meet Edward, the handsome, malaria-fighting skeeter who happens to be one of the stars of Seriously’s new mobile game, Best Fiends. 

The Best Fiends are a pack of fun-loving creatures who spend their time fighting slugs to protect the citizens of Minutia.  But Edward has his own side gig – educating the world about malaria and helping Malaria No More to beat back this awful mosquito-borne disease to protect humans!  Getting by on a diet of coconut water instead of blood, Edward changed his ways, and has developed a whole arsenal of tools to help prevent and treat the spread of this disease.

Want to help Edward end malaria?  Visit our Edward page for a whole list of ways you can support the malaria fight, and make sure to download the game on your iPhone or iPad!

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Mobile and Malaria, 2014--T:: https://www.malarianomore.org/news/entry/challenge-2-complete-cure-roger-waltzman-novartis https://www.malarianomore.org/news/entry/challenge-2-complete-cure-roger-waltzman-novartis

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge #2 focuses on the development of a single-dose cure for malaria, so we sat down with Dr. Roger Waltzman. Waltzman works for the Malaria Initiative at Novartis, the maker of one of the top malaria treatments on the market.

Q: Novartis is a pioneer in the research and development of malaria treatments. What is the quick history of innovations Novartis has been a part of?

A: Novartis is in the fight against malaria for the long haul. Together with Chinese partners, Novartis developed the first artemisinin-based combination therapy (ACT), today’s gold standard in malaria treatment, and launched the first child-friendly, dispersible formulation developed jointly with Medicines for Malaria Venture. More recently, we launched another new formulation which reduces the pill burden for adults; this helps to ensure patients follow through with their full treatment course. Today, Novartis partners with the best institutions and intensifies its research efforts to develop new compounds against malaria to eventually eliminate the disease. With two compounds in Phase 2 clinical development and one drug target in pre-clinical research, Novartis scientists are building one of the most promising malaria pipelines in the industry.

Q: What kind of treatments will it take to eliminate malaria?

A: A two-pronged approach is required to eliminate malaria. First, new treatments must be developed that attack the malaria parasites in novel ways in case resistance against current treatments spreads. These treatments will also need to provide a “complete cure”. Second, within malaria-endemic countries, a large proportion of people with malaria do not show malaria symptoms and therefore do not seek treatment for their infection. They constitute a reservoir of malaria parasites that can be transmitted to other, more vulnerable populations, therefore targeting and treating these individuals is central to achieving the goal of malaria elimination.

Q: What is a “complete cure” for malaria? How is it different from what we have today?

A: “Complete cure” implies that the treatment not only targets the parasites in the blood in their asexual stage, which is the stage when symptoms of malaria appear, but also in their sexual stage (gametocytes). Gametocytes can be harbored in the human without provoking any symptoms, and transported upon a mosquito bite, infecting other humans. A complete cure would enable a patient to be cleared from all malaria parasites. It would also stop transmission to other humans. Current treatments do not necessarily offer the potential for a complete cure.

Q: Why is a single-dose treatment important and how do you see it affecting malaria prevalence globally?

A: Developing a new combination, similar to today’s three-day ACT treatment, which is powerful enough to treat malaria in one single dose, would enable the patient to take the entire treatment at once, virtually eliminating the risk of insufficient treatment. Indeed, with current treatments patients sometimes save tablets for other family members or friends or in case they are infected by malaria again, not realizing they may be inadequately treated. Also, parasites can become resistant to treatments when dosing is inadequate. A single-dose treatment has the potential to ensure complete and effective treatment for patients. In addition, depending upon its efficacy and safety, the treatment could be given to people who show no symptoms but harbor malaria parasites in their blood, and can therefore transmit malaria. Ultimately, treatment of asymptomatic people could help eliminate the disease in broad population groups, potentially leading to malaria eradication.

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Malaria Treatments, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/challenge-2-complete-cure https://www.malarianomore.org/news/entry/challenge-2-complete-cure

Inventing a Wonder Drug to Win the Malaria Fight

The story of malaria control is the story of the promise – and peril – of wonder drugs. With hundreds of millions of people infected with malaria around the globe every year, effective treatment may be the difference between ending the disease and humanitarian disaster.

Quinine, the first antimalarial, was discovered in the bark of the cinchona tree in the foothills of the Andes Mountains back in the 1600s. But it was hard to produce and administer, and there still was no reliable global supply by World War I.

Finding a cheap, reliable alternative to quinine that could be mass-produced became a military imperative during World War II. America suffered humiliating defeats “not because the ammunition was gone,” The New York Times reported, “but because the quinine tablets gave out.”

However, the synthetic drugs that emerged from that furious R&D effort – most notably chloroquine – were little match for the fast-evolving parasite, which developed resistance in under a decade.

Progress Threatened

Our current front-line treatments for malaria, called artemisinin-based combination therapies (or ACTs for short), underscore the arms race between science and parasite. ACTs have been wildly successful in saving lives – a true wonder drug by any definition – but their effectiveness may also be cut short by resistance.

First touted for its curative powers in an ancient Chinese medical book dating back to 168 BC, artemisinin was finally brought to scale globally by Swiss healthcare company Novartis, which received WHO international approval for its drug in 1999. Global funders threw their weight behind ACTs five years later, and today more than 280 million ACT treatments are distributed every year in Africa alone.

But resistance is once again threatening to rob us of our best tool in the malaria fight. Just as chloroquine resistance emerged along the Thai-Cambodia border back in the 1960s, first signs of artemisinin resistance have now been documented in the region. If it follows the same pattern as past resistance – emerging across Asia, in India, making the leap to Africa – it could potentially cost millions of lives.

History has shown that containment isn’t an option: Only by eliminating malaria in Asia-Pacific can we staunch the spread of resistance. So the Greater Mekong subregion will be ground zero for a renewed global eradication effort.

In Search of a Solution

The race is already on to develop the next generation of wonder drugs—this time tailor-made for eradication. Such a drug would have four key features.

 



First, it would be a single-dose treatment. The pharma industry talks about the “pill burden” – the total number of pills someone has to take to complete a full course of treatment. The more pills, over more days, the greater the chance that a patient will stop midway and fail to be fully cured.

Malaria treatment currently requires between three and 14 days of treatment, depending on the strain of the parasite. Getting people to take all their pills is complicated by the fact that the drugs are so fast-acting and effective that malaria symptoms may subside after the first or second day, leading people to think they’ve been treated, when in fact trace amounts of the parasite may still be hanging around in their bodies waiting to mount another attack. A single dose treatment would ensure that everyone who is treated is parasite-free.

The second feature of a new wonder drug is that it will be a “complete cure.” Malaria is so challenging in part because the parasite plays hide and seek in the human body: traveling in the bloodstream, lodging in the liver, the brain – even bone marrow, as a recent study highlighted.

Before you can hope to eliminate malaria in a community of people, you must be able to effectively eliminate it in a single person. A complete cure treatment would wipe out the parasite at every stage of its lifecycle, ensuring zero risk of passing the parasite along to others.

The third feature is what we call a prophylactic effect. Essentially, you want a drug that will remain in the body for a period of time to prevent a person from developing another case of malaria if bitten again by an infected mosquito.

And finally, the new treatment would have a high barrier to resistance, so even as you scale up use it’s able to maintain its effectiveness. This means developing an arsenal of molecules that attack the parasite in novel ways, and then using drugs in combination to stave off resistance. New malaria drugs are a great investment, but they’re expensive to develop, so we must ensure they last.

In the Pipeline

The good news is we’re well on our way to making a new slate of wonder drugs (or “one-der” drugs) a reality. Supported by a product development partnership called Medicines for Malaria Venture out of Geneva, the malaria community and pharma industry leaders including Novartis, Sanofi, and GlaxoSmithKline have started clinical trials for treatments that will make ending malaria a reality.

As one example, Novartis has fast-tracked its first non-artemisinin based single-dose drug candidate, called KAE609, and recently published results showing that it was able to clear malaria parasites in adults in 12 hours on average. Read more about the quest for a malaria wonder drug here.

This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

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Malaria Treatments, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/femi-kuti-answers-questions-malaria https://www.malarianomore.org/news/entry/femi-kuti-answers-questions-malaria

Femi Anikulapo Kuti has been able to stand tall as an icon in the music industry without being overshadowed by the colossal image of his legendary father, Fela Anikulapo Kuti. Over the years he has blended jazz and funk with afrobeat to create a cocktail of unique indelible sounds of afrobeat, and this has earned him four nominations for the prestigious Grammy Awards.

Today Femi Kuti joins Malaria No More to have a Twitter conversation on malaria, music and the Nigerian society. It promises to be an enthralling conversation as Femi is vocal in his opinions. To join this conversation, follow the Malaria No More Twitter account in Nigeria: @MalariaNoMoreN1 and tweet your questions to Femi Kuti as from 11AM - 12PM ET using the hashtag #AskFemiKuti. Femi Kuti is currently one of the ambassadors for the Malaria No More campaign in Nigeria.

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2014--T:: https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-spotlight-on-alere https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-spotlight-on-alere

This Q&A is part of our Solve for M: Five Challenges for Ending Malaria series. Challenge #1 focuses on finding the parasite, so we sat down with Duncan Blair, PhD. Blair is the Director of Public Health Initiatives at Alere, the maker of one of the top malaria diagnostic tools on the market.

 

Q: Why are malaria RDTs a focus for your business?

With Alere being the global leader in rapid diagnostic tests for communicable diseases it would be almost impossible for us not to be involved in the malaria fight. Approximately half of the world’s population live in malaria-endemic areas, and consequently, are at risk of infection. With over 200 million infections and over 600,000 deaths a year, the risk to individuals and the burden on health care systems are enormous. To treat malaria appropriately and, just as importantly, to know when not to treat for malaria, requires accurate diagnosis. For decades, the only option for malaria diagnosis was microscopy, but microscopy is extremely challenging to implement with quality due to significant needs for complex equipment, electricity, water, well-trained and well-remunerated staff and many other reasons. The advent of the rapid diagnostic test (RDT) for malaria greatly improved our ability to diagnose malaria simply and effectively. RDTs are high quality, simple and quick tests that can be performed with just a few drops of finger-stick blood at the point of care and without any ancillary equipment. The benefits that the introduction of high-quality and properly deployed malaria RDTs have brought to individuals, to health care systems and to entire communities, is immeasurable.

Q: What are some of the new testing developments you’re working on?

We are always looking at ways to improve products or to fill a missing diagnostic need with a view of improving patient and health system outcomes. I think that we find ourselves at a time when malaria elimination is within reach and many of the tools needed to achieve that goal already exist, but not quite all of them. One of the missing pieces of the puzzle is a simple, affordable test capable of detecting the malarial parasites in asymptomatic patients. No such test exists today, but it will be critical for elimination, as we will need to find and treat patients who have no fever and no visible symptoms, but who do have circulating parasites and are therefore acting as a reservoir for future reinfection of the community. Alere is actively looking at developing just such a test.

Q: What are the key challenges you must solve to make this next-generation test a reality?

What we are talking about here is developing a test whose performance is many times better than the best tests currently available, which still meets our exacting quality standards and which can be reliably and sustainably manufactured, delivered and effectively deployed at accessible prices. We’re optimistic we can deliver that, given the great range of technologies at our disposal within Alere and the fantastic teams of dedicated and innovative people we have in R&D and manufacturing. So there may be challenges ahead, but we are very confident that we can rise to meet those challenges.

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5 challenges to end malaria, Alere, Malaria Tests, Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-find-the-parasite https://www.malarianomore.org/news/entry/5-challenges-to-end-malaria-find-the-parasite

You can't beat an opponent you can't see

Malaria thrives on misinformation. It always has. Even the word malaria is a misnomer. It’s Italian for “bad air,” because the Romans attributed the seasonal sickness (that killed at least four Popes, and probably the poet Dante) to noxious fumes coming off the swamps. It wasn’t until 1897 that Dr. Ronald Ross confirmed the mosquito as the vector that spreads the disease.

And misinformation is one of the big reasons malaria continues to kill a child at the rate of one every sixty seconds. Solving the information challenge is going to be key if we’re going to end this disease, and no piece of information is more vital than knowing who is carrying the parasite and who isn’t.

THE HIDDEN MALARIA CHALLENGE

While there are more than 200 million malaria cases every year – that is, people who are getting sick from the disease – it is estimated that there are five times as many people carrying the parasite in their bodies at any given moment – a ticking time bomb of illness and infection.

That amounts to more than one billion people – one out of every seven people on the planet – who are potentially infected with the malaria parasite, jeopardizing their health, hampering their productivity and making them a source of infection for their families and communities. And, most of them have no idea they’re carrying the potentially deadly disease!

 



The biggest host of the malaria parasite is healthy people, not sick people or mosquitoes.

The insight that sick patients showing up at clinics are only the tip of the malaria iceberg underpins emerging strategies for eradicating the disease. Simply put: you can’t beat malaria if you can’t find it. So any attempt to eradicate the disease must start with developing the diagnostic capabilities to find and free the roughly one billion people living with the parasite in their body and stop them from transmitting.

It may sound like a daunting task, until you consider how far we’ve come in recent years – and how fast.

THE DIAGNOSTIC REVOLUTION

Until 2010, there was no practical way to get a timely, accurate diagnosis for malaria. If you had a fever and wanted to be tested for malaria, you had to travel a long distance – sometimes tens of miles on foot – to find a hospital or clinic equipped with an expensive microscope and a trained lab technician. You had to take a blood slide, then wait several hours for the result – hoping that the lab technician read it right.

It was impractical, and people simply didn’t do it.

In many African languages, the words for “malaria” and “fever” are the same. It’s easy to understand why. Absent practical diagnostics, doctors simply treated every fever as if it was malaria and hoped for the best.

Then came the breakthrough: the rapid diagnostic test, or RDT. This simple, fifty-cent, finger-prick blood test can tell you in a matter of minutes with better than 99% accuracy if your fever is malaria.

The RDT has revolutionized the malaria fight, enabling lightly trained community health workers operating on the far reaches of the health system to test patients for malaria. Negative results are as important as positive ones as they direct doctors to consider other top killers, such as pneumonia and upper-respiratory infection. There are now more than 200 million RDTs distributed across Africa each year.

NEXT GENERATION TESTS

Today, we need to revolutionize diagnosis yet again, this time with a focus on identifying asymptomatic cases and guiding treatment.

Current RDTs have a sensitivity of 200 parasites per microliter of blood – sufficient for identifying all cases in sick people. But finding low-levels of the parasite in asymptomatic patients is like an elaborate game of hide and seek. To do it, we need a new generation of simple, portable, inexpensive diagnostic tests that are 10 times more sensitive, detecting malaria at levels of 20 parasites per microliter or even lower.

Fortunately, through innovative public–private partnerships led by groups like the Medicines for Malaria Venture (MMV) and Seattle-based partner PATH, we’re well on our way to developing next-generation diagnostic tests.

Other next-generation diagnostics will potentially help solve some of the treatment challenges that stand in the way of elimination. Efforts to tackle the dominant strain of malaria in Asia and South America, known as P. vivax, have been hamstrung by the fact that some people have an adverse reaction to the drug recommended for completely clearing the parasite, due to a common inherited trait known as G6PD enzyme deficiency.

The development of diagnostics to identify individuals with G6PD deficiency would ensure better use of current drugs and potential new single-dose treatments, such as tafenoquine, currently in development by GlaxoSmithKline and MMV.

Armed with new diagnostics, we’ll be in a position to take the fight to the parasite. Instead of passively waiting for sick people to show up at clinics, we can go on offense: actively testing and treating entire communities to find and root out malaria, while ensuring the type of treatment provided to patients will be safe and effective.

Which sets up the next of our challenges - check back in next week to read about another big innovation in the malaria fight: developing a complete cure!

Q&A: Read about Malaria No More’s partner Alere and their quest for new diagnostics here.

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This is one of five topics we’re covering in our new series, Solve for M: 5 Key Challenges to Ending Malaria, in partnership with Devex and the Gates Foundation. You can find others here:

Intro: Going on Offense 

Challenge 1: Find the Parasite

Challenge 2: Radical Cure (10/8/2014)

Challenge 3: Block Transmission (10/14/2014)

Challenge 4: Data & Mobile (10/21/2014)

Challenge 5: Fuel the Fight (10/28/2014)

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Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/solve-for-m-5-key-challenges-to-ending-malaria https://www.malarianomore.org/news/entry/solve-for-m-5-key-challenges-to-ending-malaria

After a century of playing defense, it’s time for the malaria fight to go on offense

In 1897, Dr. Ronald Ross – an Indian-born, British surgeon who counted poetry, mathematics, and songwriting among his other passions - made a medical discovery that would change the course of history.

Stationed in Secundebad, a monsoon-drenched city in Central India, Dr. Ross identified the malaria parasite in the gut of a dissected Anopheles mosquito. His discovery confirmed that the winged pest was in fact the vector responsible for spreading one of the oldest, deadliest, and most devastating diseases on the planet.

Dr. Ross was knighted and awarded a Nobel Prize for his efforts, and deservedly so: His discovery laid the foundation for the modern fight against malaria.

Historic Progress

We’ve made significant strides since Dr. Ross’ time. Malaria has been eliminated throughout most of the developed world, including the United States in 1951. And progress is accelerating: Just since 2000, we’ve cut global malaria deaths by half, saving 3.3 million lives - most of them children and pregnant women in Africa.

However, the work is far from done. A child still dies every minute from a mosquito bite, and more than 200 million people are afflicted with the disease each year, keeping adults out of work, children out of school, and stifling the growth of developing economies.

Based on the progress of the past decade, there is a growing determination among the global health community to eradicate the disease once and for all, recognizing that the only way to ensure zero malaria deaths is to have zero malaria.

Going on Offense

So what will it take to finish the job?

We need to rethink the malaria problem in as radical a way as Dr. Ross did more than a century ago. For all our progress, the prevailing approach to controlling malaria has fundamentally been about playing defense: trying to prevent mosquitos from biting and treating people when they’re sick so they don’t die. Don’t get me wrong. That has been the most cost-effective way of tackling a complex problem, going after the “low-hanging fruit” and bringing down the number of cases and deaths dramatically.

But to win this fight, we need to take a “parasite’s-eye” view of the problem. We must attack the malaria parasite where it lives - in the human reservoir – with aggressive new approaches to find, clear, and prevent onward-transmission of malaria, even in asymptomatic carriers of the disease. In short, we must go on offense.

As part of that approach, we need to confront one of the newest and most urgent threats to the advances we’ve made against malaria: Resistance in Asia to the frontline treatment of the disease, artemisinin. The last time drug-resistant malaria developed in that part of the world, it spread to India and Africa, robbing us of chloroquine as an effective tool.

If that happens again, it could cost millions of lives, since we are at least 4 to 5 years away from developing a viable treatment alternative.

The Path Forward

We find ourselves at another watershed moment in the malaria fight, and the only way we’re going to succeed is through relentless innovation. We need the next generation of tools and new implementation approaches; we need to harness the power of distinctly modern advances such as the use of mobile phones and big data in heatlh.

Broadly speaking, we’ve identified five key challenges the world needs to solve to win this fight. Every two weeks, starting this Monday, we’ll zero in on one challenge and let you know who’s innovating to find solutions. The series will culminate in some big news regarding the malaria community’s plan to reach eradication, delivered by one of the world’s biggest names and most prolific innovators in fighting disease, Bill Gates.

So stay tuned, and join us here next week as we launch with Challenge #1: Find the Parasite!

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This is the introduction to our new series, Solve for M: 5 Key Challenges to Ending Malaria. You can find others here:

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Solve for M, 2014--T:: https://www.malarianomore.org/news/entry/domenicos-ciao-to-malaria https://www.malarianomore.org/news/entry/domenicos-ciao-to-malaria

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

Domenico learned about our Power of One campaign through his employer, Novartis. Domenico works in the Vaccines and Diagnostics Division and is passionate about Africa. He leveraged his professional move from Italy to Switzerland to help fundraise for the campaign. At his family’s going-away party, Domenico shared stories from his travels to malaria-endemic regions in Asia and Africa, mainly Uganda, where he supports orphanages, educational institutions for disabled children, as well as projects for the economic independence of small communities. He hit a nerve and got the attention of his friends. Today, 56 have decided to support him and joined the campaign!

Domenico also hosted a garage sale to benefit the cause, which inspired shoppers to pay the full price, instead of haggling for a better deal!

“This is a cause I really care about,” says Domenico. “I have increased my personal engagement significantly, and thanks to the support of my family and friend, we will be able to help 4,128 children with malaria”. Domenico found the campaign so rewarding, that he continues to fundraise for Power of One and to engage people around him. “One of my friends – a musician – after having donated called me in the middle of the night and told me he had just composed a song for my campaign. We are now discussing how we could use the song to help fight malaria.”

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2014--T:: https://www.malarianomore.org/news/entry/eating-pizza-with-katharine-mcphee https://www.malarianomore.org/news/entry/eating-pizza-with-katharine-mcphee

Malaria No More ambassador Katharine McPhee is fighting for good on TV and in her real life. Having traveled with us to Ghana and Burkina Faso in 2012 and having supported our most recent campaign called the Power of One (Po1), Katharine had a lot to talk about with a bunch of teenagers over pizza.

Academy Award-winning composer Hans Zimmer launched a web series called Pizza with an Icon, where teens can ask questions of influencers and all the good work they’re doing. In this segment, Katharine talks about her travels and how everyone can do their part to help end malaria deaths.

"It's such a tragedy that there are people dying from something that is so easy to cure," Katharine said. "It’s important for people to know that it’s not that hard to make a dent in a small part of the world that you may not necessarily even have any connection with.”

We couldn’t be more grateful to Katharine and all her hard work on the cause.

“Katharine has been an incredible supporter of Malaria No More for years, she is truly engaged in the push to eliminate deaths from malaria,” said our CEO, Martin Edlund. “Using her platform to raise awareness for the Power of One test and treatment campaign partnered with Novartis and Alere, Katharine has made a huge impact helping us move toward achieving our goal of raising three million treatments in our first partner country, Zambia.”

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2014--T:: https://www.malarianomore.org/news/entry/support-spotlight-roger-waltzman https://www.malarianomore.org/news/entry/support-spotlight-roger-waltzman

On World Malaria Day, our partner Novartis kicked off an employee engagement effort encouraging their employees to get behind the malaria fight. From April 25th, to our Independence Day, July 4th, Novartis employees got active and joined the fight through Power of One.

Roger Waltzman, in charge of developing new antimalarials at Novartis, is one of the top contributors to this employee engagement effort, having raised over 18,000 USD towards treatments for kids in Africa. Here, he’s filled us in on his work and how he raised all that money.

Q. Why do you believe in fighting malaria, and how did this contribute to your decision to start a fundraiser?

A. I believe it’s crucial to make available high quality medical treatments for people all over the world, particularly for those vulnerable people who are at risk for preventable, curable diseases. The focus of my work at Novartis is developing new antimalarials and I wanted to generate more attention both within and outside my work environment about the importance of this effort.

Q. Did anything interesting happen while you were fundraising? Did any of your supporters do or say anything really encouraging?

A. Quite a few people didn’t know that developing new antimalarials is the focus of my work and they seemed happy to hear this and happy to contribute. I appreciated their comments; one person simply said, “Good work should be supported,” and I thought that was so matter-of-fact and genuine. Some people contributed $1, since you could contribute any amount, and others contributed much more!

Q. How has this program increased your charitable efforts this year, compared to an average year?

A. I made a personal commitment to contribute to the campaign 10% of however much money I could raise from others. That ended up being one of my largest charitable contributions this year and I was delighted to do it.

Q. Now that the employee engagement campaign is over, how will you continue your efforts to help end malaria?

A. My daily work is focused on the development of better treatment or prevention of malaria, so the biggest change is that I feel even more determined and inspired by seeing the very positive response this campaign engendered in friends and family.

Q. Is there anything else you would like to tell us about your experience with our Power of One, Malaria No More, or the Novartis employee engagement campaign?

A. I was delighted that MNM created a campaign that was so simple, with a personal link for tracking contributions, and by enabling donors to contribute as little as $1. I felt completely comfortable asking my friends, family, and colleagues to consider donating something, anything, since the amount did not need to be large. I usually don’t find fundraising a particularly comfortable activity, but this enabled me to feel very comfortable with the “ask.” I am delighted that Novartis and MNM are collaborating in this and other ways. Eradicating malaria will take a huge effort on the part of many people and we need to collaborate for the benefit of the hundreds of millions of people who are infected every year.

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Malaria Treatments, Novartis, Supporter Spotlight, 2014--T:: https://www.malarianomore.org/news/entry/the-worlds-deadliest-animal-gets-airtime https://www.malarianomore.org/news/entry/the-worlds-deadliest-animal-gets-airtime

This past World Mosquito Day we were on ABC 7’s Let’s Talk Live discussing what else but mosquitoes, the deadliest animals on the planet.

Malaria Policy Center staff Josh Blumenfeld and Hannah Bowen, as well as our partner from DC Mosquito Squad, Damien Sanchez, spoke to the threat of malaria on Wednesday’s show. Watch the full show below.

Watch the video here: http://www.wjla.com/blogs/lets-talk-live/2014/08/world-mosqutio-day-22781.html 

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2014--T:: https://www.malarianomore.org/news/entry/young-cameroonian-comic-joins-the-malaria-fight https://www.malarianomore.org/news/entry/young-cameroonian-comic-joins-the-malaria-fight

Arnold Mbolo, a high school senior from a family of six kids, joined the Junior Ambassador program in April 2014 after placing 6th with a comedic sketch in the MNM Cameroon school contest. When asked why he participated, he responded “I like challenges. I’m a competitive person. But, I realized that the contest educated me. Before, I barely knew anything about malaria, hence I have also won in knowledge.”

For Arnold, humor is something he’s been around all his life - with a professional comedian as an uncle, helping him to develop into a charismatic comedian who is responsible for “cultural animation” in his local youth association, MOJAM. In just four months, Arnold has emerged as an all-star Junior Ambassador, using his energy and comedic talents in various events at school and with MNM to ensure his community is invested in putting an end to malaria.

The goal of the Junior Ambassador Program is to engage youth leaders from high schools across Yaounde, Cameroon’s capital city, to target their peers and wider communities through interpersonal communications, including clubs, school events and other activities. Arnold has done just that. He mobilized the other Junior Ambassadors to organize a school fair at his high school, where they had a stand teaching students about malaria prevention, which was also visited by the Secretary to the Minister of Education who encouraged the Junior Ambassadors to keep doing great work. He was selected as the K.O PALU mosquito mascot for the World Malaria Day Caravan and performed his winning sketch at stops throughout the city. Arnold has also received permission from his school to post K.O. PALU educational posters and a malaria prevention mural, ensuring malaria education and awareness are a part of everyday activities at school.

For World Mosquito Day 2014, Arnold worked with a fellow Junior Ambassador to mobilize hundreds of youth and community members, the mayor, and local chief to clean up a neighborhood to get rid of its standing water – which can be mosquito breeding grounds, especially during the rainy season.

Arnold is truly leading the charge, setting an example for fellow Junior Ambassadors and his community and motivating them to join the fight against malaria.

Stay tuned for more on the amazing work our Junior Ambassadors are doing in Cameroon to ensure their communities understand the threat of malaria and know how to protect themselves against the disease.

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Cameroon, 2014--T:: https://www.malarianomore.org/news/entry/world-mosquito-day-america-africa https://www.malarianomore.org/news/entry/world-mosquito-day-america-africa

On World Mosquito Day, spoiling a BBQ is a mosquito’s most minor offense

My daughter Nell is just 8-months old, so this is her first summer. Her first taste of freshly yanked grass from the yard. Her first sunburn.

She and her big sister, 4-year-old Maret get to stay up way past their bedtimes, as we soak up what remains of the humid evenings and the lingering sunlight. And of course there’s the uninvited guest at outdoor summer events - the mosquito, that tiny but persistent blight on our backyard barbecues and pool parties.

This week at Malaria No More, we stop to acknowledge World Mosquito Day August 20th. Devoting an entire day to the mosquito may seem like overkill, until you remember that the mosquito is, in fact, the world’s deadliest living creature. This day in particular was chosen because it marks the anniversary of British surgeon Dr. Ronald Ross discovering that mosquitoes carried malaria back in 1897 – a breakthrough that set us on the path to ending this disease.

"A mosquito bite in the states only means a few days of minor irritation, rather than contracting a life-threatening disease."

As I dab the calamine lotion on the red bumps that dot Maret’s skin, I get a flash of the anxiety parents must feel in Africa, where mosquitoes lead to the deaths of more than a thousand children every day.

I remember El Hadj Diop, the Senegalese father who dedicated his life to ending deaths from malaria in his home community after losing his 11-year-old daughter, Ami, to the disease. I’m haunted by the face of the nameless Nigerian dad I encountered as he arrived, desperate, at a clinic with his daughter on the verge of a malaria coma. Pictures of both fathers hang above my desk.



Above:  El Hadj holds up a picture of his deceased daughter; a Nigerian father holds his malaria stricken daughter

These are but two examples of the African parents who lose their precious children to a mosquito bite every minute of every day. And my eyes well up at the prospect of that happening to Nell or Maret. We’re lucky here in the U.S., where malaria was eradicated in 1951. A mosquito bite in the states only means a few days of minor irritation, rather than contracting a life-threatening disease.

The good news is that we can help protect children who still live with the reality of a potentially deadly mosquito bite. Just one dollar buys and delivers a life-saving test and treatment for a child in Africa through our Power of One campaign, thanks to our partnership with Alere and Novartis.

So this World Mosquito Day, please consider contributing. With your help, we’re closer than ever to mosquitoes becoming just another summer nuisance alongside sunburns and brain freezes, instead of the world’s most deadly predator.

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2014--T:: https://www.malarianomore.org/news/entry/u.s.-senate-staff-see-government-malaria-investments-overseas https://www.malarianomore.org/news/entry/u.s.-senate-staff-see-government-malaria-investments-overseas

For many Americans, it’s difficult to see the impact foreign aid has on people half a world away. We’re working hard to close that gap, and bring stories from malaria endemic countries home. That’s why, last week, we brought three Senate staffers to Dakar, Senegal and Geneva, Switzerland; where the staff learned firsthand the impact malaria has across all aspects of the Senegalese health system. They also experienced the inspiring progress that Senegal has made with the help of partners like the U.S. President’s Malaria Initiative (PMI) and the Global Fund to Fight HIV/AIDS, TB, and Malaria, to which the U.S. is the largest donor.

Day 1

The week kicked off in Dakar with meetings at the U.S. Embassy and Senegal’s National Malaria Control Program, where staffers heard from the program officers on the ground working to eliminate malaria about challenges and successes in the region. We learned how malaria fits within a broader health and economic context in the region, and why so many parts of the Senegalese government, private sector leaders, and development partners are committed to fighting malaria. The PMI Resident Advisor helped to guide us around and explain how PMI’s staff from USAID and the CDC support Senegal’s health system.

Day 2

Tuesday started bright and early with a short drive to the Peace Corps Headquarters in Ngor where the team was briefed by Country Director Cheryl Gregory Faye and Vanessa Dickey, Director of Programming & Training, then boarded a van for the almost two-hour drive to Thies, where we saw the great work Peace Corps volunteers are doing to combat malaria as part of their continent-wide “Stomp Out Malaria in Africa” program. We even Skyped with volunteers from other countries who are implementing the same community-based case management strategies that were developed in Senegal and which are now in Benin, Madagascar, and other countries. Over a lunch of delicious family-style Senegalese yassa chicken, we heard presentations from current Peace Corps volunteers about some of the major challenges they face in the area, including commodity stock outs, village access and communication. We learned what they are doing in partnership with PMI to overcome these obstacles and stomp out malaria.

 

Senegal Peace Corps & SLAP Lab

Above: Lunch with the Peace Corps; visit to SLAP lab

In the afternoon we were able to see cutting-edge research taking place at the Parasite Control Service. Dr. Sy and Dr. Ndiaye presented the monitoring and research activities which are supported by various US governmental and higher education institutions including the NIH, CDC, USAID, Peace Corps as well as Tulane and Harvard Universities. The lab, although subject to challenges like fluctuating electricity (our demonstration of the microscopy center was cut short by a power outage), is helping track insecticide resistance and studying the genetic markers of parasites to track parasite populations over time. The day ended with two site visits, one to a larger health center in Thies and another smaller health hut in Keur Madaro, where we had the opportunity to meet the community leaders and health workers.

Day 3

On Wednesday, the team headed out to see another key global malaria partner, PATH. The PATH country director explained PATH’s work to strengthen the health system in Senegal through community empowerment and malaria prevention and treatment. After a brief visit and presentation from young members of the Malaria No More Club in a nearby school, the staff headed to a lunch, hosted by MNM’s long-time partner, Senegalese NGO Speak Up Africa, with key business leaders to hear why they care about malaria and what they are doing to stop malaria from draining Senegal’s economy. The ideas proposed by bankers, builders, and leaders of other industries included issuing a malaria bond, setting up a health investment fund, and contributing in-kind expertise and materials to the fight – something several leaders in the room pledged to do.

We made a quick stop to see a warehouse where the Long Lasting Insecticidal Nets procured with PMI funding are housed before being distributed nationwide, then arrived to our last meeting in Dakar with the Minister of Health, Dr. Awa Marie Coll-Seck. Given her previous experience as Roll Back Malaria’s Executive Director, the Honorable Awa Marie Coll-Seck’s vast knowledge of malaria allowed our time to be more of a working session than a typical courtesy call. During the hour she spent with the team, the Senate staffers were able to report back what they found from their time in Dakar, including the challenges of supply chain management to rural areas, but also the successes of the partnership between PMI and the inspiring staff of the National Malaria Control Program.

 

Senegal LLIN & Minister of Health

Above: Visit to the LLIN warehouse; meeting with the Minister of Health

The Minister of Health also spoke about Senegal’s commitment to pre-elimination and its challenges and strategies for tackling the higher-burden southeastern regions, such as indoor residual spraying and seasonal chemo-prevention for children. She also stressed the need for private sector engagement, and shared that she was very pleased to have presented Senegal’s story at the official health event during the trade and investment themed U.S. Africa Leaders Summit in Washington, D.C. the week before.

Geneva

After an overnight flight to Geneva, the team ended the trip with debriefing meetings to link the lessons from Senegal with broader global strategies for malaria and innovation for the next wave of the fight.

Experts from the Global Fund, the WHO’s Global Malaria Programme, Medicines for Malaria Venture, and MNM’s Power of One partner Novartis all shared their perspectives on the global fight against malaria, answered the staff’s questions in great detail, and closed out a busy, but productive, week.

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Advocacy, Senegal, 2014--T:: https://www.malarianomore.org/news/entry/how-ebola-makes-malaria-more-deadly https://www.malarianomore.org/news/entry/how-ebola-makes-malaria-more-deadly

If you’re even a casual consumer of news, you’ve likely heard plenty about New York City resident Eric Silverman, who was hospitalized recently at Mt. Sinai hospital after displaying symptoms of Ebola.

While the media went into overdrive, it turns out that the Brooklyn man – who recently returned from Sierra Leone – was likely suffering from malaria. The mistake is understandable, since the two diseases display similar symptoms - such as fever, headache, and aching joints. As The Gothamist headline joked, “Ebola Man" Probably Just Had Boring Malaria.

The Ebola fears are well justified: As the death toll in West Africa surpassed 1,000, the World Health Organization recently approved the experimental use of drugs to try to save infected patients. But the reality is that “boring” malaria kills more people every day - about 1,700 - than have died in the Ebola outbreak to date. And, with the rainy season underway in West Africa, the Ebola outbreak may compound malaria’s deadly effects. As Bloomberg reports, Sierra Leone residents suffering from malaria are staying away from health clinics and hospitals, fearing they may be quarantined or infected with Ebola from a sick patient.

Unlike Ebola, we have simple cost-effective treatments for malaria. They key is getting them in time, since kids can die within the first 24 hours of the onset of malaria symptoms.

So, as health officials tackle the Ebola crisis, they must take special pains to encourage people to seek timely testing and treatment for similar-seeming illnesses, so “boring” malaria doesn’t become even more deadly.

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2014--T:: https://www.malarianomore.org/news/entry/asia-the-next-frontier-in-the-malaria-fight https://www.malarianomore.org/news/entry/asia-the-next-frontier-in-the-malaria-fight

MNM staff just returned from Singapore, where we held an official event to kick-off our partnership to fight malaria with the Asia Pacific Leaders Malaria Alliance (APLMA) and the Asian Development Bank (ADB). 

The Asia-Pacific region is home to more than two billion people at risk of malaria infection and accounts for 32 million cases of malaria each year. Recently, resistance to the front line treatment to the disease, aretemisin-based combination therapies (ACTs), has emerged in the Greater Mekong Region. This is a major concern to the public health community, as ACTs are the most effective way to treat malaria, and past resistance to malaria treatment has spread from Asia to Africa, where most cases of the disease occur.

The reception celebrating the new collaboration took place at the St. Regis Hotel in Singapore with attendance from both private sector and government leaders including Alere, the American Chamber of Commerce, Bayer, Chevron, ExxonMobil, Edelman, Kimberly-Clark, and US Embassy and Australian officials.

While many of the business leaders in the room understand the importance of defeating malaria in the region, the goal of the event was also to take advantage of their expertise and resources to leverage engagement across additional sectors.  To that end, MNM staff heard directly from the private sector representatives, including a presentation from Alere, about strategies to garner support within their organization as well as effective ways to engage new champions in the business world.

The event was a great start in helping to deepen the bench for the Champions of APLMA, which will be a major focus of the new partnership. The group will build a coalition of private sector leaders in Asia-Pacific to raise the profile of malaria as a massive roadblock to the region’s social and economic progress, and to advocate for the elimination of the disease in Asia and beyond.

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Advocacy, Asia, Malaria Policy, 2014--T:: https://www.malarianomore.org/news/entry/from-malaria-victim-to-malaria-victor https://www.malarianomore.org/news/entry/from-malaria-victim-to-malaria-victor

Malaria No More’s Supporter Spotlight series shines a light on people from around the world who share one thing in common – a commitment to finally bring an end to malaria.

Today’s supporter, Chinweike, is what we at MNM call a super supporter. When his company, Novartis, encouraged him to take part in fundraising for our Power of One campaign, he set himself a lofty goal – to raise $1,500. Through Po1, that’s enough to provide malaria tests and treatments to 1,500 African children. And not only did Chinwe achieve his goal, he far surpassed it – raising $12,347! In fact, his personal fundraiser was so successful that he had to raise the bar for himself after just two days, as he had already met his initial $1,500 goal. For him it was more than just participating in a Novartis employee engagement effort. It was personal.

Growing up in Nigeria, Chinwe suffered from malaria during his childhood, as did many of his family members. Chinwe, who is now working at the Novartis Institutes for BioMedical Research, beat tough odds. While major progress has been made since he was a child in Nigeria, malaria still takes a massive toll on the world’s children - with a child dying every minute from the treatable disease.

Though he left the country as a teenager, he says his ties to the continent still remain. He has taken part in African medical and education programs since leaving, and was especially drawn to the scale and ambition of the Power of One effort, which has already raised enough money to provide malaria treatments to two million children. “A death a minute for a preventable and treatable disease is just unacceptable,” says Chinwe. “To be able to change a life with a dollar is quite a bargain.”

Chinwe’s passion for Po1 was contagious. Though he had just started in his position, he used the campaign as a way to connect with new co-workers. He took the message everywhere he went – from work, to the airport, to his monthly poker game – he even fundraised at a couple’s engagement party! And his family is just as excited about the cause as he is. His 10-year-old son and 8-year-old daughter offered up their savings to be donated. His wife sent messages to her friends and family soliciting donations, and made sure Chinwe was actively fundraising through some good-natured spousal nagging.

And the impact was incredible – as Chinwe says he’d never given or raised even a third of what he did through Power of One. And he plans to continue raising money for the campaign throughout the year.

While Chinwe provided enough money to test and treat more than 12,000 children for malaria, he says he benefited from the effort as well. “It was a great thrill doing this,” he says. “I have reconnected with a host of great friends and colleagues from my pre-Novartis days, and in less than six months at the company I already know I have wonderful colleagues and friends I can count on.”

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Malaria Tests, Malaria Treatments, Novartis, Power of One, 2014--T:: https://www.malarianomore.org/news/entry/20750-nets-for-pregnant-women-and-children https://www.malarianomore.org/news/entry/20750-nets-for-pregnant-women-and-children

Thanks to MNM’s generous international donors, MNM Cameroon was able to purchase 20,750 long lasting insecticide treated mosquito nets (LLINs).

The majority of the nets will go to the two populations who need it the most: pregnant women and children. Malaria attacks these two groups the most viciously, where 45% of malaria deaths are children under 5, and pregnant women suffer from miscarriages and birth complications.

The nets will also be used as prizes for community sensitization activities and radio contests to engage the public and test their malaria knowledge.

MNM Cameroon donated 15,000 LLINs to the Ministry of Public Health to be distributed to pregnant women during their antenatal visits in health centers in the Center region, where net possession is the lowest. When a pregnant woman goes in for her prenatal care, she will receive this three-year-lasting net, and as of her fourth month of pregnancy the health centers also provide her with free Intermittent Preventative Treatment (IPT), which protects her and her baby from malaria.

In Cameroon a child is lost every four hours to this killer. Mosquito nets are still the most efficient protection against malaria, but unfortunately orphanages are not covered by the universal net distributions.

Because of this - and in honor of the International Day of the African Child in June - MNM Cameroon went to four different children’s centers to teach 160 orphans, abandoned and disadvantaged children and caregivers about malaria. K.O. PALU Junior and Senior Ambassadors donated food to the orphanages, performing malaria themed songs and leading an interactive quiz with exciting prizes. After the sensitization session, nets were installed on each of their beds.

In Yaoundé, MNM was invited to join in on Day of the African Child celebrations at two centers in collaboration with “Association des Jeunes pour un Comportement Positif” (AJECP- an association founded and led by a former MNM intern) and “Hope for All.”

At one of the centers in Yaoundé, K.O. PALU Ambassador and Percussionist Zorobabel performed with his cute and talented sons for the first time. After his performance, the children performed a creative malaria-themed sketch, which included using headphones for a stethoscope.

In the Southwest, Peace Corps Volunteers stationed there came out to help, as did K.O. PALU Ambassador and singer Sine and Radio Balafon’s Cyrille Bojicko.

To increase the chances of the nets being used, MNM aired them out in advance and directly installed the nets after the sensitizations. With the help of the ambassadors, the team also put up posters in each center that encourage mosquito net usage.

After the installation of nets, every child received a bracelet and sticker to encourage them to sleep under their bed nets nightly in order to be healthy and fulfill their dreams.

Caregivers and the center’s directors testified about the malaria cases they have endured, including one 8-month-old baby who died from malaria. They expressed their gratitude toward COTCO-ExxonMobil for the net donation, promising to ensure the children use and maintain the nets regularly and appropriately. They all believe they will now suffer fewer cases of malaria thanks to these nets!

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Cameroon, Mosquito Nets, 2014--T:: https://www.malarianomore.org/news/entry/70000-children-treated-through-venmo1 https://www.malarianomore.org/news/entry/70000-children-treated-through-venmo1

Your friend just paid you to split a cab ride, and you just purchased a malaria treatment for a child in Africa. It’s that easy! Through mobile payments provider Venmo, people all over America have been donating to our Power of One platform as part of their everyday lives.

When we launched Power of One, we wanted to make it so effortless to treat a child for malaria that you could do it while going about your daily business. When we met Venmo, a mobile app that lets you easily pay your friends back for a beer or concert ticket and socialize it in your newsfeed, we not only realized that this was attainable, but that the platform’s socially engaged user base could create a massive impact.

As of today, Venmo donors have provided a whopping 70,000 malaria treatments to children in Zambia, a total of $35,000 in one-dollar treatments, which was matched with 35,000 treatments provided by our Power of One partner, Novartis.

Users were able to donate with just one tap on their phone while cashing out their Venmo balance to their bank account. Even cooler, they could donate through their newsfeed! Any time a payment was made to Malaria No More, the payment would appear in their friends’s newsfeed, along with a hyperlink to create a one-touch donation of their own. The result was a viral loop of donations, and Venmo users had tons of fun with all of the social features that came with it (see below).

We’d like to extend a huge thank you to Venmo for their innovative efforts to end malaria deaths, and to our treatment partner Novartis for matching the impact that was made. Through the help of our partners and supporters, we’re one step closer to finally making malaria no more!



Venmo users having fun while treating kids for malaria

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Mobile and Malaria, 2014--T::

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Tue

18

Nov

2014

Drones Are Taking Pictures That Could Demystify A Malaria Surge



Researchers download images after a drone flight in Sabah, Malaysia.

Courtesy of Trends in Parasitology, Fornace et al

hide caption

itoggle caption

Courtesy of Trends in Parasitology, Fornace et al

Researchers download images after a drone flight in Sabah, Malaysia.

Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes.

Courtesy of Trends in Parasitology, Fornace et al

hide caption

itoggle caption

Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes.

Courtesy of Trends in Parasitology, Fornace et al

Aerial drones are targeting a new enemy: malaria.

Four hundred feet above a Malaysian forest, a three-foot eBee drone hovers and takes pictures with a 16-megapixel camera every 10 to 20 seconds. But it's not gathering images of the mosquitoes that transmit malaria. Even today's best drones aren't capable of such a photographic marvel. Rather, the drone is looking at a changing landscape that holds clues to the disease's spread.

The malaria drone mission, described in a study published Oct. 22 in Trends in Parasitology, began in December 2013, when UK scientists decided to track a rare strain of the mosquito-borne disease that has surged near Southeast Asian cities. Understanding deforestation may be the key in seeing how this kind of malaria, known as Plasmodium knowlesi, is transmitted.

The mosquitoes that carry P. knowlesi are forest dwellers. The insects breed in cool pools of water under the forest canopy and sap blood from macaque monkeys that harbor the malaria parasite.

In Sabah, Malaysia, human cases of this kind of malaria didn't surface until about 10 years ago, says infectious disease specialist Kimberly Fornace of the London School of Hygiene and Tropical Medicine. She is leading the drone study.

While cases of the most common malaria strains have steadily dropped during this time, P. knowlesi has thrived. It's now the number-one cause of malaria in the region. Fornace and her team suspect that human intrusion into forested areas has created more opportunities for the disease to pass between primates and humans via mosquitoes. The drone imagery they've collected so far suggests there were occasions where land development forced macaques within closer proximity of humans, who then developed malaria.

As part of a project called MONKEYBAR, the team tracks outbreaks by comparing the drone's land surveillance with hospital records of malaria cases. Meanwhile, a local wildlife commission has fitted macaques with GPS collars, which let scientists monitor the locations of monkey troops. Together, this information paints a public health map that explains how land development has influenced monkey movements -- and transmission of malaria to humans. In partnership with Conservation Drones, an organization that builds drones for under $1,000, Fornace and her team plan to build a drone that snaps thermal images of macaques, so the monkeys can someday be identified without GPS collars.

Drones provide a better surveillance picture than satellite images, which are the current standard for mapping environmental changes. But Google Earth images, for example, are only updated every few weeks or months, says parasitologist Chris Drakeley of the London School of Hygiene and Tropical Medicine, who coauthored the Trends in Parasitology study with Fornace. Drones, he says, can provide a more comprehensive, continuous picture: "We avoid cloud cover and can see what the land use was like today, next week and the week after."

The public health implications of drone use extend far beyond malaria, says Harvard epidemiologist Nathan Eagle. Doctors have already used unmanned aircraft to carry medical supplies between rural clinics in South Africa and Haiti. Humanitarian drones also tracked property damage and hunted for survivors after Typhoon Haiyan. And when a disease like Ebola surfaces, a drone could scan for changes in bats' habitats, given that the winged mammals are proposed carriers of the hemorrhagic fever. The prices of these drones are dropping while their specs -- flight performance and cameras -- are improving, says Eagle. All of which means in a few years, a series of very inexpensive aerial vehicles will exist for wider use in public health research.

http://www.npr.org/blogs/goatsandsoda/2014/10/22/357637900/drones-are-taking-pictures-that-could-demystify-a-malaria-surge?utm_medium=RSS&utm_campaign=malaria
0 Comments

Mon

17

Nov

2014

Drones Are Taking Pictures That Could Demystify A Malaria Surge



Researchers download images after a drone flight in Sabah, Malaysia.

Courtesy of Trends in Parasitology, Fornace et al

hide caption

itoggle caption

Courtesy of Trends in Parasitology, Fornace et al

Researchers download images after a drone flight in Sabah, Malaysia.

Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes.

Courtesy of Trends in Parasitology, Fornace et al

hide caption

itoggle caption

Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes.

Courtesy of Trends in Parasitology, Fornace et al

Aerial drones are targeting a new enemy: malaria.

Four hundred feet above a Malaysian forest, a three-foot eBee drone hovers and takes pictures with a 16-megapixel camera every 10 to 20 seconds. But it's not gathering images of the mosquitoes that transmit malaria. Even today's best drones aren't capable of such a photographic marvel. Rather, the drone is looking at a changing landscape that holds clues to the disease's spread.

The malaria drone mission, described in a study published Oct. 22 in Trends in Parasitology, began in December 2013, when UK scientists decided to track a rare strain of the mosquito-borne disease that has surged near Southeast Asian cities. Understanding deforestation may be the key in seeing how this kind of malaria, known as Plasmodium knowlesi, is transmitted.

The mosquitoes that carry P. knowlesi are forest dwellers. The insects breed in cool pools of water under the forest canopy and sap blood from macaque monkeys that harbor the malaria parasite.

In Sabah, Malaysia, human cases of this kind of malaria didn't surface until about 10 years ago, says infectious disease specialist Kimberly Fornace of the London School of Hygiene and Tropical Medicine. She is leading the drone study.

While cases of the most common malaria strains have steadily dropped during this time, P. knowlesi has thrived. It's now the number-one cause of malaria in the region. Fornace and her team suspect that human intrusion into forested areas has created more opportunities for the disease to pass between primates and humans via mosquitoes. The drone imagery they've collected so far suggests there were occasions where land development forced macaques within closer proximity of humans, who then developed malaria.

As part of a project called MONKEYBAR, the team tracks outbreaks by comparing the drone's land surveillance with hospital records of malaria cases. Meanwhile, a local wildlife commission has fitted macaques with GPS collars, which let scientists monitor the locations of monkey troops. Together, this information paints a public health map that explains how land development has influenced monkey movements -- and transmission of malaria to humans. In partnership with Conservation Drones, an organization that builds drones for under $1,000, Fornace and her team plan to build a drone that snaps thermal images of macaques, so the monkeys can someday be identified without GPS collars.

Drones provide a better surveillance picture than satellite images, which are the current standard for mapping environmental changes. But Google Earth images, for example, are only updated every few weeks or months, says parasitologist Chris Drakeley of the London School of Hygiene and Tropical Medicine, who coauthored the Trends in Parasitology study with Fornace. Drones, he says, can provide a more comprehensive, continuous picture: "We avoid cloud cover and can see what the land use was like today, next week and the week after."

The public health implications of drone use extend far beyond malaria, says Harvard epidemiologist Nathan Eagle. Doctors have already used unmanned aircraft to carry medical supplies between rural clinics in South Africa and Haiti. Humanitarian drones also tracked property damage and hunted for survivors after Typhoon Haiyan. And when a disease like Ebola surfaces, a drone could scan for changes in bats' habitats, given that the winged mammals are proposed carriers of the hemorrhagic fever. The prices of these drones are dropping while their specs -- flight performance and cameras -- are improving, says Eagle. All of which means in a few years, a series of very inexpensive aerial vehicles will exist for wider use in public health research.

http://www.npr.org/blogs/goatsandsoda/2014/10/22/357637900/drones-are-taking-pictures-that-could-demystify-a-malaria-surge?utm_medium=RSS&utm_campaign=malaria
0 Comments

Tue

11

Nov

2014

Which Contagious Diseases Are The Deadliest?



Do you know what the deadliest disease is? Hint: It's not Ebola (viral particles seen here in a digitally colorized microscopic image, at top right, along with similar depictions of other contagious diseases) NPR Composite/CDC hide caption

itoggle caption NPR Composite/CDC

Do you know what the deadliest disease is? Hint: It's not Ebola (viral particles seen here in a digitally colorized microscopic image, at top right, along with similar depictions of other contagious diseases)

NPR Composite/CDC

No one knows what the death toll in the Ebola epidemic will be. As of Tuesday, nearly 2,500 people have died and nearly 5,000 have caught the virus, the World Health Organization says.

So how does this epidemic compare with the toll taken by other contagious diseases?

Comparing fatality rates could help put the current Ebola outbreak in perspective. Trouble is, getting an accurate value for many diseases can be hard, especially in places where the health care infrastructure is weak.

Take the situation in West Africa right now. "We can only count those who come to the doctor, not those who stayed home and got well, or those who stayed home and died," says Carol Sulis, an epidemiologist at Boston University School of Medicine and the Boston Medical Center.

Another issue is that "deadliest" can mean two things. It can refer to the fatality rate -- the number of deaths per number of cases -- or it can mean the number of deaths in total caused by a disease.

What's more, diseases can take a different toll in different parts of the world. In low- and middle-income countries, only limited medical care may be available, if that. This will raise the fatality rate for many infectious diseases, such as tuberculosis, malaria and infectious diarrhea.

"Similar to Ebola, people's chances of survival increase for most of these [contagious] diseases, some dramatically, if people receive medical treatment," says epidemiologist Derek Cummings, at the Johns Hopkins Bloomberg School of Public Health.

Even if lists have their limitations, they can shed light. We spoke to Cummings and Sulis and consulted data from the World Health Organization and the U.S. Centers for Disease Control and Prevention to come up with two lists: the deadliest contagious diseases by death toll and by death rate if untreated.

Data are for all fatalities in 2012, except for infectious diarrhea and pneumonia. For those, death tolls represent a yearly estimate and represent childhood victims only.

Deadliest Contagious Diseases By Death Toll

Comparison point: As of Sept. 7, the number of reported deaths in the current Ebola epidemic is 2,218.

HIV/AIDS: 1.6 million deaths

Even though HIV takes a tremendous toll each year, the population of people living with the disease is about 35 million.

Since antiretroviral therapy -- ART -- became available in the mid-1990s, life expectancy for someone infected with HIV has dramatically increased. Today, a person who is promptly diagnosed with HIV and treated can look forward to a close-to-normal life span.

But as with other diseases, Sulas says, "we have to have the infrastructure to find the cases and be able to afford the medicine and deliver it to those affected."

Tuberculosis: 1.3 million deaths

Despite the death toll for this airborne disease, there is encouraging news: 7.3 million people developed TB and survived in 2012.

Recovery requires a regimen of several drugs over a six- to nine-month period. Patients who don't follow the drug schedule can develop drug-resistant TB. Drug-resistant forms of TB are also airborne. For those patients, treatment can extend to two years.

Pneumonia: 1.1 million children under the age of 5

It's the world's leading killer of children, "more than AIDS, malaria and tuberculosis combined," WHO says. The risks are also high for the elderly and those with other underlying conditions. In rich countries, like the U.S., vaccines can prevent the disease, but that is not the case in much of the world.

Infectious Diarrhea: 760,000 children under the age of 5

"That's an enormous waste," Sulis says. The majority of cases (about 1.7 billion globally each year) could be prevented and treated with better hygiene and sanitation, along with access to clean food and water. "There are many pathogens" that can cause these infections, she says, "but the whole class of diseases categorized as infectious diarrhea is deadly."

Malaria: 627,000 deaths

The world records about 200 million malaria cases each year. According to WHO, "most deaths occur among children living in Africa where a child dies every minute from malaria."

There's a growing worry for both malaria and TB, Sulis says, because "the organisms that cause those diseases are becoming increasingly drug resistant throughout the world."

Deadliest Contagious Diseases By Fatality Rate (If Not Treated)

Here, as in the list above, fatality rates can be lowered significantly depending on the presence of sanitary conditions and the availability of medical care and vaccines.

We present the diseases that appear to have the highest fatality rates if not treated. If the rate is a range, we ranked the disease by the highest possible fatality rate.

Comparison Point: Outbreaks of Ebola can have fatality rates up to 90 percent, WHO says. But in the current outbreak, it's about 50 to 60 percent.

Rabies is nearly 100 percent fatal if not treated. There are approximately 55,000 deaths each year, primarily in Asia and Africa.

Doses of the rabies vaccine after a bite from an infected animal will essentially abort the disease. But a person must receive treatment immediately. Initial symptoms include discomfort where the bite occurred, anxiety and agitation. Once clinical signs such as delirium and hallucinations arise, the patient almost always succumbs.

Creutzfeldt-Jakob disease is apparently 100 percent fatal.

This neurodegenerative disease rapidly progresses. It is caused by prions (nonviral, nonbacterial infectious agents that consist of a misfolded protein) that damage healthy brain tissue. Prions create holes in the brain that make it look like a sponge under the microscope.

CJD is classified as a contagious disease because it can be transmitted through contact with contaminated tissue during medical procedures. But it's not spread through the air or by casual contact.

No treatment exists for CJD. Its incidence is very low, affecting about 1 in 1 million people each year, with about 300 cases annually in the U.S. CJD can be difficult to diagnose because symptoms often resemble those of dementia and other diseases, with memory lapses, behavioral changes and sleep disturbances.

Marburg hemorraghic fever: 24 to 88 percent

Marburg is caused by a virus similar to Ebola, transmitted mainly by contact with bodily fluids from someone who's been infected. Fever, chills, headache and muscle pain are the first symptoms, showing up within five to 10 days after infection. The next stage can cause vomiting, diarrhea, delirium and organ dysfunction or failure. There's no known treatment beyond supportive hospital therapy. Since 1967, when Marburg was first recognized by scientists, there have been 571 reported cases.

H5N1 and H7N9 flu viruses: 60 percent for the former, 25 percent for the latter

These two viruses "remain two of the influenza viruses with pandemic potential," WHO says. They're in wide circulation among some groups of poultry; humans do not appear to have any immunity. The total number of human cases for both viruses so far is about 1,000. Some antiviral treatments and vaccines are available.

Middle East respiratory syndrome: 41 percent

First detected in 2012, this illness can lead to coughing, shortness of breath, fever and pneumonia. When patients die, the cause may be a lack of oxygen passing from the lungs into the blood. Scientists theorize that MERS could have first appeared in bats, which passed it to Arabian camels, which may then have infected humans. The majority of the 800 cases have been on the Arabian Peninsula.

http://www.npr.org/blogs/goatsandsoda/2014/09/16/347727459/which-contagious-diseases-are-the-deadliest?utm_medium=RSS&utm_campaign=malaria
0 Comments

Wed

05

Nov

2014

Drones Are Taking Pictures That Could Demystify A Malaria Surge



Researchers download images after a drone flight in Sabah, Malaysia. Courtesy of Trends in Parasitology, Fornace et al hide caption

itoggle caption Courtesy of Trends in Parasitology, Fornace et al

Researchers download images after a drone flight in Sabah, Malaysia.

Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes. Courtesy of Trends in Parasitology, Fornace et al hide caption

itoggle caption Courtesy of Trends in Parasitology, Fornace et al

The map above combines drone images with yellow dots that track the movement of macaques as determined by a GPS collar. The red dot indicates a human case of malaria, which can spread from macaques via mosquitoes.

Courtesy of Trends in Parasitology, Fornace et al

Aerial drones are targeting a new enemy: malaria.

Four hundred feet above a Malaysian forest, a three-foot eBee drone hovers and takes pictures with a 16-megapixel camera every 10 to 20 seconds. But it's not gathering images of the mosquitoes that transmit malaria. Even today's best drones aren't capable of such a photographic marvel. Rather, the drone is looking at a changing landscape that holds clues to the disease's spread.

The malaria drone mission, described in a study published Oct. 22 in Trends in Parasitology, began in December 2013, when UK scientists decided to track a rare strain of the mosquito-borne disease that has surged near Southeast Asian cities. Understanding deforestation may be the key in seeing how this kind of malaria, known as Plasmodium knowlesi, is transmitted.

The mosquitoes that carry P. knowlesi are forest dwellers. The insects breed in cool pools of water under the forest canopy and sap blood from macaque monkeys that harbor the malaria parasite.

In Sabah, Malaysia, human cases of this kind of malaria didn't surface until about 10 years ago, says infectious disease specialist Kimberly Fornace of the London School of Hygiene and Tropical Medicine. She is leading the drone study.

While cases of the most common malaria strains have steadily dropped during this time, P. knowlesi has thrived. It's now the number-one cause of malaria in the region. Fornace and her team suspect that human intrusion into forested areas has created more opportunities for the disease to pass between primates and humans via mosquitoes. The drone imagery they've collected so far suggests there were occasions where land development forced macaques within closer proximity of humans, who then developed malaria.

As part of a project called MONKEYBAR, the team tracks outbreaks by comparing the drone's land surveillance with hospital records of malaria cases. Meanwhile, a local wildlife commission has fitted macaques with GPS collars, which let scientists monitor the locations of monkey troops. Together, this information paints a public health map that explains how land development has influenced monkey movements — and transmission of malaria to humans. In partnership with Conservation Drones, an organization that builds drones for under $1,000, Fornace and her team plan to build a drone that snaps thermal images of macaques, so the monkeys can someday be identified without GPS collars.

Drones provide a better surveillance picture than satellite images, which are the current standard for mapping environmental changes. But Google Earth images, for example, are only updated every few weeks or months, says parasitologist Chris Drakeley of the London School of Hygiene and Tropical Medicine, who coauthored the Trends in Parasitology study with Fornace. Drones, he says, can provide a more comprehensive, continuous picture: "We avoid cloud cover and can see what the land use was like today, next week and the week after."

The public health implications of drone use extend far beyond malaria, says Harvard epidemiologist Nathan Eagle. Doctors have already used unmanned aircraft to carry medical supplies between rural clinics in South Africa and Haiti. Humanitarian drones also tracked property damage and hunted for survivors after Typhoon Haiyan. And when a disease like Ebola surfaces, a drone could scan for changes in bats' habitats, given that the winged mammals are proposed carriers of the hemorrhagic fever. The prices of these drones are dropping while their specs — flight performance and cameras — are improving, says Eagle. All of which means in a few years, a series of very inexpensive aerial vehicles will exist for wider use in public health research.

http://www.npr.org/blogs/goatsandsoda/2014/10/22/357637900/drones-are-taking-pictures-that-could-demystify-a-malaria-surge?utm_medium=RSS&utm_campaign=malaria
0 Comments

Tue

04

Nov

2014

A $1 Microscope Folds From Paper With A Drop Of Glue



All folded up and ready to magnify: The Foldscope weighs less than two nickels, is small enough to fit in your back pocket and offers more than 2,000-fold magnification. TED/YouTube hide caption

itoggle caption TED/YouTube

All folded up and ready to magnify: The Foldscope weighs less than two nickels, is small enough to fit in your back pocket and offers more than 2,000-fold magnification.

TED/YouTube

We have pocket watches, pocket cameras and now — with smartphones — pocket computers.

So why shouldn't doctors and scientists around the world have pocket microscopes?

Origami microscope: Lines on the paper show you how to fold up and assemble the microscope.

Courtesy of Prakash lab

Bioengineer Manu Prakash and his team at Stanford University have designed a light microscope that not only fits in your pocket but costs less than a dollar to make.

And here's the coolest part: You put the microscope together yourself, by folding it.

Imagine all the uses for this so-called Foldscope. Even in the poorest corners of the globe, doctors and scientists could use the pocket scope to diagnose common bacteria and pathogens, such as giardia, Chagas and malaria.

Here's how it works.

Using Foldscope is simple: Stick the glass slide in the middle pocket and look through the lens. The microscope even has a stage.

Courtesy of the Prakash lab

"So the starting material looks really like a flat sheet of paper," Prakash says.

That's because, well, it is a flat sheet of paper. But it has a thin plastic coating that makes it sturdier and resistant to tearing, Prakash says.

Then he and his team run the paper through a special printer that actually prints a lens on the paper. "You should think of it as a drop of glue, a tiny drop of glue," he says, "except it is an optical-quality glue."

The printer also prints lines on the paper, showing people where to make the folds that will align the light on the lens so the microscope will work.

It turns out people can fold paper quite accurately, Prakash says. "So that's one of the things that is hidden in the design that allows us to make instruments that are very precise, but actually are just made by people folding a simple sheet."

And all the components of the Foldscope are quite cheap. When you manufacture 10,000 devices:

The sheet of paper costs 6 cents.

The lens costs between 17 and 56 cents, depending on the type of lens and microscope.

Add in an LED light for 21 cents.

A battery for 6 cents.

An on-off switch for 5 cents.

And a few other bits and bobs, and you've got a microscope for less than a dollar.

Prakash says he expects some people will use the microscope in schools. And others will find them useful in clinics or laboratories for doing simple medical tests or for making field repairs of small electronic equipment. But he's sending the Foldscopes out to many people around the world, hoping they'll find uses for them that he can't even imagine.

"By the end of the summer," he says, "we'll be shipping 50,000 of these microscopes to 130 countries, and then just watch what happens." Or to put it another way: He'll see what unfolds.

http://www.npr.org/blogs/goatsandsoda/2014/09/03/345521442/a-1-microscope-folds-up-from-paper-and-a-lens-of-glue?utm_medium=RSS&utm_campaign=malaria
0 Comments

Wed

29

Oct

2014

The requested URL could not be retrieved



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http://blog.againstmalaria.com/syndication.axd?format=rss
0 Comments

Tue

28

Oct

2014

The requested URL could not be retrieved



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Your cache administrator is root.

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0 Comments

Wed

22

Oct

2014

Ntcheu, Malawi 33-month post-distribution check-up will start on 13 Oct 14

Monitoring net use and condition is an important element in optimising the protection of a population at risk from malaria.

This will be the fourth post-distribution check-up (PDCU) of net use and net condition in Ntcheu, Malawi following the June 2012 net distribution that achieved district-wide universal coverage of the population of some 550,000 people.

9,500 households, representing approximately 7% of those that received nets 33 months ago, will be randomly selected and visited unannounced.

The results will assist the District Health Officer (DHO) and National Malaria Control Programme’s (NMCP) decision as to when a re-coverage campaign should be conducted in Ntcheu so the people of Ntcheu remain protected.

http://blog.againstmalaria.com/post/2014/10/01/Ntcheu-Malawi-33-month-post-distribution-check-up-will-start-on-13-Oct-14.aspx
0 Comments

Tue

21

Oct

2014

Drug-Resistant Malaria Spreads Across Southeast Asia



Yonta, 6, rests with her sister Montra, 3, and brother Leakhena, 4 months, under a mosquito net in the Pailin province of Cambodia — an epicenter of drug-resistant malaria. Paula Bronstein/Getty Images hide caption

itoggle caption Paula Bronstein/Getty Images

Yonta, 6, rests with her sister Montra, 3, and brother Leakhena, 4 months, under a mosquito net in the Pailin province of Cambodia — an epicenter of drug-resistant malaria.

Paula Bronstein/Getty Images

Back in 2008, doctors in Cambodia made a worrisome discovery. They were having a hard time curing some people of malaria.

Even the most powerful drug wasn't clearing out the parasite from patients' blood as quickly as it should. Malaria had evolved resistance to the last medicine we have against it, a drug called artemisinin.

Adam Cole/NPR/YouTube

What do Jesuit priests, gin and tonics, and ancient Chinese scrolls have in common? They all show up in our animated history of malaria.

At the time, scientists thought they might be able to keep this dangerous form of malaria from spreading, says biologist Carole Sibley, of the University of Washington.

"There has been a hope that we could keep drug-resistant malaria in the Pailin province of Cambodia," she says. "That you could launch a massive intervention, cast a ring around it and extinguish it."

Now all those hopes have been dashed.

A study published Wednesday in the New England Journal of Medicine found that artemisinin-resistant malaria is common throughout mainland Southeast Asia. It's cropped up in Thailand, Laos, Vietnam and Myanmar, an international team of scientists reported.

"The take-home message of the study is clear," says Sibley, who wasn't involved in the study. "Drug-resistant malaria hasn't stayed in Pailin."

Although there's no evidence yet that the dangerous type of malaria has spread outside Southeast Asia, scientists are looking for it in Africa and fear it could easily jump over to nearby India.

Artemisinin comes from a shrubbery plant, called sweet wormwood. The Chinese have used wormword extracts for thousands of years to treat fevers, and artemisinin drugs were highly effective in Cambodia for decades.

So why has the drug lost its potency recently?

Researchers aren't sure, says Dr. Christopher Plowe, of the University of Maryland School of Medicine, who contributed to the study. "But now that drug resistance has occurred, it seems to be spreading pretty rapidly."

It looks like the parasites in Southeast Asia have picked up a few mutations in their DNA that make it easier for them to evolve drug resistance, Plowe says.

It's like the parasites have a genetic predisposition for picking up resistance, he says, just like some people have a genetic predisposition for gaining weight or getting a specific type of cancer.

The good news, though, is that artemisinin can still cure nearly all malaria infections when it's mixed with other drugs. "It just takes longer to clear the parasite out of the blood [in some cases]," Plowe says. "Instead of taking a day or two after starting treatment, it can take up to four or five days," he says.

Artemisinin is the last approved drug that can cure any type of malaria around the world. But there are a few new medicines in the pipeline. One from the pharmaceutical company Novartis can clear the parasite from blood in about 12 hours, a preliminary study found.

"The new drug looks promising," Plowe says. "But it's only been tested in very small studies. So it will be some time before that's available."

http://www.npr.org/blogs/goatsandsoda/2014/08/05/336594646/drug-resistant-malaria-spreads-across-southeast-asia?utm_medium=RSS&utm_campaign=malaria
0 Comments

Wed

15

Oct

2014

396,900 nets on the way to Dowa District, Malawi



396,900 nets have shipped and will arrive in Dowa district in the middle of November for distribution from Dec14/Jan15 to protect 720,000 people and achieve universal coverage.

Our distribution partner Concern Universal will carry out the distribution.

AMF is funding both net and non-net costs, as was the case with the Balaka (2013) and Dedza (2014) distributions. We describe publicly the circumstances in which we cover non-net costs for a distribution.

A cost-driver led budget has led to detailed costings and we publish full budget details. Actual costs will be published at the end of the distribution.

The non-net cost per net is US$0.97. This covers shipping, pre-distribution activities (a district-wide household level registration to establish sleeping space net need), distribution and post-distribution follow-up (six, six-monthly check-ups of 5% of households, randomly selected and visited unannounced, carried out for three years post-distribution). 

http://blog.againstmalaria.com/post/2014/10/07/396900-nets-on-way-to-Dowa-District-Malawi.aspx
0 Comments

Tue

14

Oct

2014

Volunteer Recap: A Bumpy (And Itchy) Ride Through Tanzania



Nick Stadlberger in Africa. Courtesy of Nick Stadlberger hide caption

itoggle caption Courtesy of Nick Stadlberger

Nick Stadlberger in Africa.

Courtesy of Nick Stadlberger

Nick Stadlberger, a fourth-year medical student at Dartmouth College spent four weeks this spring in Dar es Salaam, Tanzania, working in the infectious disease ward at Muhimbili Hospital as part of his school's global health program.

Each day began at the gates of the hospital, where Stadlberger watched people come and go – from families visiting their loved ones to patients with crutches that seemed to be made of sticks found in the road. Then he'd go in and do his rounds, helping treat HIV patients suffering from tuberculosis, renal failure and infections that take advantage of the weakened immune systems.

Here's what he saw outside the hospital in Tanzania — and the advice he has for volunteers-to-be.

Something you wish you'd brought from home?

Bug spray, totally forgot that. I had a lot of bites, and there was a time when I felt like I was getting sick, which made me worried about malaria. I had gotten malaria previously in Ghana and I really didn't want it again.

What woke you up aside from your alarm clock?

The heat. Or my itching bug bites.

Guilty pleasure?

There was a dish called chips mayai – essentially a French fry omelet. They always served it to you with a huge mound of salt on the side. I've never put salt on anything in the U.S., but there I took up the habit of eating a ton of sodium. I would cover my French fry omelet with that and be about as unhealthy as you can be.

Scary moment?

The name dala dala comes from the word "dala," local slang for the five shillings that used to be the standard fare, equivalent to one U.S. dollar

We got on a dala dala bus to go to a soccer game, and our driver apparently wasn't watching the traffic. All of a sudden, everyone ahead of us came to a stop and he swerved out of the way, almost hit a bus, swerved again, ran into the back of a man who was biking — pedaling a whole bunch of corn – and there was corn everywhere. He swerved again, and we careened down into a ditch. All the passengers flew to the left side, the seats came loose and the entire interior of the bus came apart. We all had to crawl out of the window. Luckily, I don't think anyone was severely hurt.

What happened afterward?

I limped home that night and told one of the gatekeepers that we had been in a car wreck. I don't know what I was expecting – some type of sympathy or "Oh my gosh!" – but he just nodded. He said, "This is the type of thing that we have to live with every day."

Best thing you brought back home?

We went scuba diving off the western coast of Zanzibar and I brought back a scuba diving certification.

Epiphany?

In the U.S. we take our good health for granted, and people place a lot of blame on doctors who aren't able to fix things, whereas in Tanzania, any health care they get is considered a privilege.

Tweet of advice?

Go with the flow. Don't make rigid plans because they're not going to work out.

http://www.npr.org/blogs/goatsandsoda/2014/07/09/319514471/volunteer-recap-a-bumpy-and-itchy-ride-through-tanzania?utm_medium=RSS&utm_campaign=malaria
0 Comments

Mon

10

Mar

2014

Senate Democrats Plan An All-nighter Monday For Climate Change

Majority Leader Harry M. Reid (D-Nev.) has pledged in recent weeks to continue allowing time for anyone who wants to discuss the issue during the weekly Democratic caucus lunch or on the Senate floor. The format planned for Monday is an extension of floor speeches given regularly by Whitehouse that usually begin with him saying that "it's time to wake up" to climate change. Reid and his three lead deputies -- Sens. Richard Durbin (D-Ill.), Charles E. Schumer (D-N.Y.) and Patty Murray (D-Wash.) are scheduled to participate Monday, along with Boxer, Schatz, Whitehouse and 21 other Democrats. The group includes the Senate's two independents, Angus King (I-Maine) and Bernie Sanders (I-Vt.), and other mostly liberal members of the 55-member caucus. Notably absent from the list are Democrats facing difficult reelections this year in states that President Obama lost in his two elections. Only two Democrats who might face tricky reelections -- Jeanne Shaheen (D-N.H.) and Mark Udall (D-Colo.) -- are on the list of expected speakers.
For the original article including any supplementary images or video, visit http://www.washingtonpost.com/blogs/post-politics/wp/2014/03/07/senate-democrats-plan-an-all-nighter-monday-for-climate-change/

0 Comments

Sun

02

Mar

2014

Internet Of Things Can Battle Climate Change

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For the original article including any supplementary images or video, visit http://www.usatoday.com/story/money/personalfinance/2014/03/02/internet-battle-climate-change/5899331/

0 Comments

Thu

27

Feb

2014

Sudden Climate Change Threw Ancient South Asian Civilization In Decline

Even if a direct causal link is not found between this event and the decline of the Indus Civilization, the fact remains that the two phenomena coincide remarkably well. Unlike other cultures, the Indus Civilization was capable of building metropolises, and spanned parts of northern India and most of modern-day Pakistan. The conclusions in this new study may suggest that climate change is one of the main reasons why many large, ancient cities fell into ruin. The presence of the weak monsoon was determined through an in-depth analysis of snail shells found inside sediments at the bottom of an ancient lake. Cambridge investigators analyzed the amount and type of oxygen isotopes in these shells in order establish weather conditions at the time. This is one of the first pieces of evidence supporting the older hypothesis that climate change may have had a hand in the decline of the Indus Civilization and its major cities. Furthermore, the work supports an idea which argues that a global climate change event occurred on Earth during the Bronze Age.
For the original article including any supplementary images or video, visit http://news.softpedia.com/news/Sudden-Climate-Change-Threw-Ancient-South-Asian-Civilization-in-Decline-429730.shtml

0 Comments

Sat

22

Feb

2014

Climate Change: Accelerated Melting Of Arctic, Antarctic Sea Perilous To Earth

Ramez Naam, explained it this way: Heres how: Ice and snow reflect light. Thick ice covered with snow will reflect the large majority of the suns energy back into space, absorbing only 10 to 20% of the sunlight as heat. Ocean water, on the other hand, reflects very little of the suns energy back into space, absorbing more than 90% of it as heat. Naam points to the following causes for disappearing sea ice, which he calls the triple whammy: Warming from the greenhouse gases we emit already. Warming from the loss of ice and permafrost in the Arctic, and the exposure of dark water and dark land below.
For the original article including any supplementary images or video, visit http://www.examiner.com/article/climate-change-accelerated-melting-of-arctic-antarctic-sea-perilous-to-earth

0 Comments

Thu

20

Feb

2014

The Need For Asian Climate Leadership

It's a Western problem, we said. They caused the problem by dumping greenhouse gasses into the atmosphere; let them clean it up. Instead, we Asian leaders focused on reducing poverty by growing our economies. We were not responsible for the pollution, we argued; so we should not have to pay for it. Yes, Asia's industrialisation was quietly building up toxic stores of carbon, but we were only following the rich world's prescription for success. Carbon equals growth, it said; and, like those who took up smoking on the doctor's orders, we were not to blame. There was a time when the assumptions underpinning this line of thinking were true.
For the original article including any supplementary images or video, visit http://www.huffingtonpost.com/mohamed-nasheed/climate-change-asia_b_4814980.html

0 Comments

Fri

14

Feb

2014

“meet The Press” To Host Climate Change “debate” Between Gop’s Marsha Blackburn And Bill Nye “the Science Guy”

I intend no disrespect to Mr. Nye, who is a smart and dedicated evangelist for science and advocate for action to address carbon emissions. But Bill Nye is not actually a climate scientist. He is a former mechanical engineer turned television entertainer, and now professional edu-tainer. Hes clearly well-informed on the subject of climate science, and he has done quite a lot to popularize and explain the research. Against very well-funded opponents, he has long been a prominent voice for scientific literacy. I have no doubt that Bill Nye could out-debate Marsha Blackburn or indeed pretty much any Republican elected official on the subject of humanitys responsibility for climate change and its probably catastrophic effects. Whats insulting (and insane) is that there is to be a debate at all, on one of Americas supposed premier news talk shows.
For the original article including any supplementary images or video, visit http://www.salon.com/2014/02/14/meet_the_press_to_host_climate_change_debate_between_republican_marsha_blackburn_and_kids_show_host_bill_nye_the_science_guy/

0 Comments

Tue

11

Feb

2014

Why Climate Change Is Very Bad For Your Health

And climate change is making us sick. Sealevel rises, changes to the severity of monsoon seasons and rainfall, flooding, droughts and Author PhD Candidate in Epidemiology and Public Health at University College London Disclosure Statement Geordan Shannon does not work for, consult to, own shares in or receive funding from any company or organisation that would benefit from this article, and has no relevant affiliations. Provides funding as a Founding Partner of TheConversation. ucl.ac.uk Alastair Mackies Mosquito Coast. Noodlefish It is beyond doubt that our emissions contribute to climate change. And climate change is making us sick. Sealevel rises, changes to the severity of monsoon seasons and rainfall, flooding, droughts and heatwaves are all predicted to have an increasing impact on our health.
For the original article including any supplementary images or video, visit http://theconversation.com/why-climate-change-is-very-bad-for-your-health-22965

0 Comments

Sat

08

Feb

2014

Q & A With Rolly Montpellier, Founder Of Boomerwarrior.org

Im a Climate Change leader and presenter. BoomerWarrior is the perfect name for the website. Im a Baby Boomer and now a Warrior outraged by the kind of world weve created. How could I not have seen this before? BoomerWarrior allows me to dialogue, to share my opinions, to scream for change and assume my responsibility for ensuring a better future for my children and grandchildren. I owe them that much. That will be my legacy.
For the original article including any supplementary images or video, visit http://www.examiner.com/article/q-and-a-with-rolly-montpellier-founder-of-boomerwarrior-org

0 Comments

Wed

05

Feb

2014

Big Surprise: Ken Ham’s Creationism Extends To Climate Change Denial

Theres been climate change ever since the flood of Noahs day, he asserted. And anyway, he said, the climates currently in a state of cooling. Bill Nye looked on, horrified, throughout all of this (or, as Morgan described it, with a look of vague bafflement on his face). Morgan then attempted to explain to Ham that, by not believing in global warming, he was in the massive, if vocal, minority. I didnt even tell you what I believe about global warming, Ham interrupted to say. I didnt say I believe in global warming.
For the original article including any supplementary images or video, visit http://www.salon.com/2014/02/05/ken_ham_mans_fall_is_responsible_for_climate_change/

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Mon

02

Dec

2013

Attempting To Save Money On Your New Boiler Installation Is A Big Mistake

Attempting To Save money on heating costs is one of the most typical reasons that individuals decide to acquire a new boiler or change their old one. For that reason, lots of people are tempted to cut corners on the installment process to further decrease the costs included. However this can be unsafe and is illegal in the majority of locations, and it can wind up costing you more in repair works and damages than exactly what you conserve by not working with an expert. To find Gas Safe engineers and installers in your local area Click

Even if you are a mechanically inclined person who has actually reviewed the owner's manual of your new boiler cover to cover multiple times, attempting to install a boiler without professional aid is dangerous and might even be deadly. Boilers usually operate by transforming natural gas into heat, which in turn converts water into steam, and a single error or skipped action in the process of installment could bring about catastrophe.

The Importance of Hiring a Professional

Since setting up a boiler includes working with gas lines, it is unlawful to try the process yourself unless you are a licensed gas worker. Therefore, when looking for out a professional, it is necessary to look into the qualifications of the individual you are hiring; there are as lots of individuals out there planning to make a quick dollar doing an inexpensive job as there are individuals planning to save cash with DIY solutions. If asked, really qualified specialists need to be registered with Gas Safe and able to produce credentials as proof.

Another thing to bear in mind when looking for a professional to install your new boiler is that there is often is commonly electrical work that requires to done as well. While finding an employee who is certified to work with both gas and electricity is uncommon, it never hurts to ask; otherwise you could end up spending as much as two times the cash employing 2 different professionals.

A Few Ways to Reduce the Cost of Installation

Despite the problem and risk connected with the majority of the tasks that installing a brand-new boiler involves, there are a couple of things that you can do to decrease the quantity of time your employed help spends on the clock. When your brand-new boiler shows up, if it is not provided by the expert installing it, go on and thoroughly eliminate it from its product packaging.

Also, try to have a concept of where you 'd like your boiler to be set up. Remember that it ought to be as close as possible to your gas and water lines, as both will require to be linked to the boiler, and minimizing this distance will reduce the products and labor the setup needs.

Cutting edges in the setup procedure can possibly save cash for both you and the person responsible for installing your boiler, but doing so undoubtedly brings about breakdowns and repairs in the near future. Therefore, it is essential that you work with an educated professional who has a reputation for high-quality work.
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Mon

02

Dec

2013

4 Essential Things To Look For When Picking Ski Apparel



If you are considering purchasing new Ski Clothes, there are numerous considerations including cost and fashion to remember. Nevertheless, prior to taking a look at either of these elements it is important to think about the 4 essential things that should be built into any great quality product of ski clothing. They are: waterproofing, insulation, breathability and seam sealing. When shopping for ski gear, this article talks about these important qualities to help you to make the finest choices. Snowboarding is an expensive sport and the most important thing is to enjoy your time on the slopes. There is no point in looking superb if you are feeling unpleasant during the experience.. You will find a great selection of ski clothing on http://www.theskicondo.com

Waterproofing

Lots of people are of the understanding that waterproofing and insulation are the exact same thing and that all Ski Clothes will naturally feature both. This is not always the case, especially with less costly products of ski or snowboard clothing. Waterproofing is and is the outer layer developed to keep rain and snow from penetrating to the inner layers of the garment. Typically the very best snowboarding conditions are when it is in fact snowing so it is important to have a garment with a high waterproofing rating so that you can stay out in these conditions for numerous hours whilst staying dry. Waterproof scores are determined in millimetres (mm). The greater the score of the product, the much better the waterproofing homes, nevertheless it likewise indicates the higher the price. 5,000 mm is usually considered appropriate and anything over 10,000 mm will provide you with extremely excellent protection under many situations.

Insulation

Insulation is usually separate to the waterproofing layer and is designed to keep you warm. Previously insulation was really large. However, modern technological innovations in the products used to make Ski Clothes have actually led to exceptional fabrics that are comfortable and light whilst providing exceptional insulating homes.

Breathability

When snowboarding or snowboarding, while it is vital to keep the aspects out. It is similarly essential for moisture from sweating to get away from continually. When it is referred to in relation to Ski Clothes, that is what the term breathability suggests. Snow sports are high energy sports and if your clothes doesn't allow sweating to escape your base layer of clothing can become wet quickly. You frequently will not observe this while you are really snowboarding or boarding. It is when you stop or are riding ski lifts that you will get cold due to having damp clothing. Breathability is measured the same as waterproofing, in mm; where entry level products of ski and snowboard garments will certainly have a score of 3,000 mm to 5,000 mm whilst the top of the range will certainly have around 20,000 mm.

Taped and Sealed Seams

All the above is of no use if moisture can enter through the seams of your Ski Clothes. When you are out in the aspects for long times of time you will end up very moist and cold if your garments permits moisture to enter with the zippers or seams. More than most likely they will likewise have taped and sealed seams if you buy quality Ski Clothes that are accredited to have the various other 3 qualities mentioned here. Modern identifying ways that it is easy to identify the quality and ratings of ski jackets and pants, so make sure that you check prior to purchasing.

In fashion, price and conclusion are typically considered when purchasing Ski Clothes nevertheless the four points below are essential. If you are on a budget plan, you should look around for deals on high quality items instead of purchasing cheap quality ones. The very best times to purchase are just prior to the season starts or towards completion. You will also discover deals online that are of high quality but may just be last year's models.
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Sat

16

Nov

2013

Exactly How You Could Use A Photo Booth At A Wedding Reception

You can make use of a photo booth to entertain guests at your wedding reception and make the event more unforgettable. Great pictures will be considered your own use and visitors can also take home their pictures. There are few options for you in this regard; you can lease a photo booth from a rental business, set up a DIY booth that your visitors can work with a photographer or operate to man a booth for you. You may wish to Hire a Devon Wedding Photo Booth

It is essential for you to determine if you are going to rent a photo booth from a neighborhood rental business or established one for yourself. Nevertheless, the most convenient solution is booth rental due to the fact that guests will have the opportunity to print out their images instantaneously and take them home. If you are thinking about a rental, you ought to also find out about any constraints. A lot of companies have limits for the number of photographs that can be taken or the number of hours for the rental. Likewise, it is necessary to learn about pick-up and delivery information in order to be furnished with the right info.



Additionally, the photo booth must be placed in a location of the reception where its disturbance with various other events will be prevented. For instance, it is not perfect to have it in the background when you and your brand-new spouse are being photographed cutting the cake or dancing. There need to be easy access to it but it must out of the means of service personnel.

You must string a clothesline in between poles or close-by trees if you will be setting up the booth on your own. Thereafter, you should connect curtain clips to the top of a huge piece of material in a color that matches the color scheme of your wedding and the clip loops need to be stringed onto the clothesline. If a free wall is readily available, you only should nail the fabric onto the wall. A tripod of about 9 feet must be set up in front of the fabric background and affixed to a cam. The angle needs to be checked to make sure that the subjects and material background are the only things that reveal in the viewfinder.

The camera to be used have to be of high quality and you could hire a photographer to set it up along with guy it for you. The photo booth must be made self-serving so that guests will have the freedom of posturing as they feel. A printer needs to be linked to the video camera so that visitors will have the opportunity of taking the images house. You can likewise affix a shutter release or remote wire to the video camera so that visitors will have the opportunity of taking pictures themselves without touching the camera.
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Tue

12

Nov

2013

A College Degree Or Even Possessing The Appropriate Skill Set Is No Longer Sufficient To Get A Job

After everything is completely structured and the resume looks and reviews expertly, most job applicants do not seriously think about the next phase. For most job candidates, the interview phase which is the next phase if you are successful in your application, is where lots of fail 'impress' and are typically ruled out. These are applicants with the right education, the right skills, and have actually shown high professionalism from their past experience. If you're considering a complete change of career then following link takes you to a site with information on a whole variety of different careers and professions including Alarm Installation as a Career

The technique of 'thrilling' is knowing that companies will not want education or previous job experiences if they do not include value to their company. For this reason exactly what this means for a task seeker is that they have to reveal exactly how their proficiencies can be of value to the prospective customer employer. Otherwise they might constantly discover themselves hitting the wall of failure at interviews.

Right here are some useful suggestions if you discover yourself in such a fixed scenario:.

Accentuate the positive - This pointer primarily works if your previous work experience is not related to the job you have actually obtained. Apply this idea by chatting about how your previous work experience instructed you how to deal with an actual deadline, how it instructed you to work in a team and sharpen your interpersonal skills, exactly how you learned the best ways to utilize high-end devices and software for this reason you might not need much training, and above all exactly how you got to discover practical abilities that might not be found out in your university.

Focus on solving the company's requirements - Employers deal with a strict budget plan and therefore you need to show them your value to persuade them to bring you on board. Hence before you react to an ad on a paper or a job board, research the information keenly and comprehend exactly what kind of worker is needed. By this understanding you can look into your past work experience and list and try down any attributes during your work experience that match up or are carefully related to exactly what the ad is looking for. Focus on the troubles you can resolve with this characteristics which will demonstrate how valuable your past work experience is to this brand-new job position.

Stay clear of assumptions - When pitching during the interview process, attempt and cover all loose ends. This indicates, never assume that your prospective customer employer will determine exactly how your ability set and possibly education will accomplish his or her objectives. Describe further. For example if her challenge is viewership and you are interviewing for a task as a journalist, do not mention how you have the necessary skill set and education that is needsed in writing. Instead explain how you when developed a brand-new idea for a collection of features that aired and overtime enhanced viewership.

Take a proactive approach - By being proactive you can get the job even if you fail throughout the interview stage. When talked to for a position as a Digital Copy Writer and was not successful in getting the job, a friend of mine. However by being creative and applying a proactive technique, he used his well-researched knowledge of the business to encourage the employer to bring him on board as a short-term hire. This got him a possibility to prove himself and he was later hired under a long-term basis.

Do not await the employer to assist you in the working with process. Whether by acting on your application or using up particular lower job positions. Success is always within your reach. Nonetheless if you discover it tough, try and get some training from a reputed human resource management company.
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Mon

11

Nov

2013

Some Suggestions Concerning Christmas Gifts For A 10 Year Old Boy

What do you get a 10 years of age boy for Christmas?

What are his interests?

By the age of 10, a kid would very much have a strong viewpoint about what he desires. He might be completely insane about Pokemon, or basketball with hopes of signing up with the school team. You will find a selection of Christmas gifts for children of all ages on Best 2013 Toys.

At that age, exactly what his peers think about him is crucial. He 'd want to be with the in group. To have what the cool children in school have. Perhaps a mobile phone or an MP3 player. Or the incredibly yo-yo. Or whatever's the present trend in school.

Exactly what he suches as is not necessarily what his dad suched as when he was 10 years old. Father could have enjoyed Lego sets and Star Wars when he was 10 years old. If you ask a 10 years old today if he 'd such as a light saber or something from Star Wars for Christmas, he's most likely to provide you a blank look.

The in-thing now that my ten-year old and his friends love are nerf guns.



Boys love weapons. Toy weapons or anything they can shoot with, or battle with will complement the boys. However the moms and dads may not like such gifts. Specifically if the children end up breaking and antique vase or something as expensive in the home, while having fun with these Christmas gifts.

Moms and dads would be much happier if you get the children useful presents. Like garments. Or pajamas.

At that age, boys do get especially dissatisfied when they unpack the gift, to discover that it is a brand-new set of pajamas or some garments or stationery. Uninteresting. Unless the boy does such as dressing up and you took place to choose an outfit he definitely loves. Get him clothes if you know the boys taste and size perfectly and he is the type who suches as dressing up. If not, then get a much safer gift.

Is the boy into sports?

If he is absolutely into soccer or baseball or basketball, does he such as to conform or see it?

A gift that features his team or his favored player would be well gotten if he has a personal favorite group. Get him brand-new gear if he enjoys the game.

When he opens your Christmas gift, Match the gift to the boy's interest and he would be delighted.
1 Comments

Wed

30

Oct

2013

A Few Ideas About Working For Yourself

It's time for some changes if you are weary and sick of your dull job, reduced pay, or lousy boss. Self work has the unbelievable potential to alter your life permanently. Sure the concept appears scary at first. Going into business for yourself has many dangers and little protection, however it also has the incredible potential to significantly improve your life. Think of a life without an employer. You can make your own schedule and work when you desire. There is no more worrying about office politics, missed promos, low wage increases, or corporate restructuring. As soon as you become self utilized, you are in charge. Your income will be absolutely based on you and nobody else. The following link takes you to a site with information on Becoming A Piano Tuner

Independent Contractors

Whether you are looking for self employment concepts that will make you rich or merely add versatility to your life, there are loads of options that can be done at house. The list of self work ideas below provides you with just a few of the many possibilities for individuals who desire to work from house.

Blog writer - Believe it or not, the basic act of establishing and keeping a blog site can sometimes generate a great deal of money for the site owner. The basic is to produce a blog that produces considerable amounts of traffic to your business website. This is not constantly simple to do however. You need to frequently produce distinct content that provides value to all the people seeing your site. Websites that generate enough traffic are then able to earn earnings through advertisement income. Selling ad space, advertising affiliate products, or using Google's AdSense program are a variety of profits streams that bloggers can capitalize on.

Freelance Writer - This covers a broad variety of writing styles. As a freelance writer you can compose for a variety of print publications including newspapers, magazines, and diaries. There are likewise a lot of chances for freelance composing jobs online. Freelance authors often contribute content to authority internet sites, blog sites, merchant business website, and affiliate websites. Some of the finest locations to search for jobs or market your services are oDesk, Elance, and Freelancer.

Medical Transcriptionist - This a fantastic job that the majority of people are certified to do from their house. A clinical transcriptionist, likewise referred to as an MT, takes a doctor's voice recordings and transfers them into writing. There are no particular requirements for this occupation, however there are a number of training programs offered. Getting certification from the Association for Healthcare Documentation Integrity (AHDI) is a wonderful way to get begun in the field.

Virtual Assistant - Imagine a secretary that works from home and you'll understand what a virtual aide is. With outsourcing becoming ever more widespread, many office jobs can be done by independent professionals all over the world. A virtual assistant frequently provides the same services as an internal management assistant.

Online Teacher - Believe it or not, teaching has gone virtual. Specifically in the field of ESL (English as a Second Language), online teachers are being searched for. In foreign nations all over the world, the costs of working with a native speaking English teacher is generally quite high. Long times exclusive lessons will cost anywhere from $50 to $100 per hour. A growing number of foreign nationals are relying on the web for cheaper options. This has actually opened an extraordinary chance to teach English from your home. Some self work ideas are limited based upon your education. The very best part about this opportunity is that you don't should be certified and even have teaching experience. There are a number of websites, consisting of Verbal Planet and WizIQ, which allow you to establish lessons with students. This is likewise an easy business to establish on your own. Simply post ads in the Seoul, Tokyo, or Taipei area of Craigslist. All you need to conduct your lessons is a dependable internet connection and Skype.

Affiliate Marketer - As far as at-home self work concepts go, this is one of the most popular. There are a number of various methods to do this. The most common way is to produce a website that drives web traffic to business sites. You will receive commissions when customers stemming from your website purchase their products or services if you are part of that business's affiliate program. The problem is available in creating quality traffic. Unless you are paying for traffic, you are reliant on Google's search engine result. This can be bothersome as Google is continuously altering the method they see websites and subsequently place them. There are various web marketing e-books, internet sites, and programs that can assist you begin.

Beginning a Business

Outside of the self employment concepts that need high levels of education (doctor, dentist, vet, attorney, designer, and so on.) there are a number of various other methods to go into company for yourself.

Franchise Business Owner - This is among the best and best methods to go into company for yourself. Purchasing into a trusted franchise system provides you with a variety of advantages. A great franchiser offers large-scale advertising campaigns, a popular brand name, and a tested system. There is still no assurance of success, however a great deal of the risks that startup business owners face are prevented.

Start-up Business Owner - Of all the self work concepts we've covered, this is by far the riskiest and most tough to prosper at. If you have a wonderful start-up company idea, nevertheless, It can likewise end up being the most lucrative. Start-ups are for the real entrepreneurs. If you've got an innovative brand-new product or a remarkable concept that you believe fills an important demand or want, then by all means offer it a shot. One of the secrets to obtaining a startup off the ground is financing. You need adequate cash to give your business a genuine shot at success. See to it you have sufficient capital to cover your operating costs for a minimum of 6 months. And keep in mind, the majority of businesses take some time to succeed. it could take as long as 2 to 3 years before your business becomes profitable.

Turnkey Business Owner - A turnkey business is a recognized company that is prepared for operation when offered. Buying a turnkey business is among the best means to limit your risk. If looked into properly, you can buy a successful company that will instantly provide earnings. All self work ideas come with risk, however any means you can restrict that danger will benefit you in the long run.
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Tue

22

Oct

2013

Discovering The Advantages Of Hiring A Photo Booth At Your Event

Visitors can enter the booth with their partners, children, or as a group and have a substantial amount of fun catching amusing images. The ability to tape-record messages and an entire memory cd will offer the hosts with a wonderful gift. Whether you want to share the images in the future, or keep them all to yourself, the photo booth is an excellent way to keep everybody entertained. For more information about hiring a photo booth in Cornwall Click Here

There are several different photo booths which you can hire; nevertheless, you should ensure that you pick a quality business. This style of entertainment is not low-cost; for that reason, you desire to ensure that the booth can operating all night to a high standard. Bigger booths are considered more enjoyable, and will hold up to eight individuals, making them optimal for team pictures.



You will have the ability to communicate with all your visitors, and make sure that people have photos to take house, which are premium and enjoyable. It takes a superb picture each time, making sure that nobody loses out on an opportunity for those entertaining postures. If the event is a wedding or birthday, you may desire to capture a household picture, for that reason, the booth needs to completely open.

If you pay even more for the booth, you are most likely to be able to select both white and black, and color photos. This can make a big difference, and include another aspect to the photo booth hire, making it incredibly appealing. You will also should decide the number of copies of each it will produce. Some will only print one for your records, which is no fun for your guests.

Putting in the time to select the finest photo booth hire companies will assure that you have leading quality equipment at your occasion. You require to ensure that you clarify all information ahead of time consisting of times, restrictions and any additional charges. Many booths will be provided with certified, experienced individuals who will continue to be with the devices for the duration of the celebration - it's a great deal of fun!

If you make sure that you study beforehand, and select the company carefully, your guests will be talking about your photo booth and event for months. Every event that follows will should match the requirement of your occasion, and unless there is photo booth hire, this will be challenging to attain.

Photo booths do cheer up lots of occasions with unique memories in years to come!
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Mon

21

Oct

2013

Finest Toddler Toys For Girls

Wish you had a list of the finest toys for young girls? Some of the most memorable times you'll have with your young child are those times when they wish to pretend to be all grown up. The world of grownups appeals to children and playing at tending house has constantly been a favorite activity to play amongst kid girls. You will find a great selection of toys for young girls on This Toys Website



From cooking food on playsets of pots and pans to putting that food onto plastic play dishes, kids can constantly discover the fun. While playing housekeeping, one thing little toddler girls take pleasure in having is their personal infant to care for.

They'll invest hours speaking to their infant, feeding it and rocking it to sleep, even presuming regarding shush anybody talking loudly so their wee one does not get up too quickly from a nap.

There are unique dolls made just for your unique kid and among those dolls is the Corolle Mon Premier Calin Candy Pink doll. It's a 12 inch doll that's simply the best size for a toddler's arms. This honor winning doll is soft and simple to look after plus, you can purchase relevant accessories to support the doll that will equip your toddler to be an excellent mommy - simply like her own!

Even when they're quieter, kids still like to engage in play. When the hours of busy play are winding down, your child will take pleasure in being able to 'review' books on her personal with the LeapFrog Tag Junior book pal.

Since kids at this age are still finding out through touch, by utilizing guide Pal, they'll be presented to the terrific world of reading in a manner that holds their interest. With 130 responses as they experience guide, toddlers will wish to come back once again and again to discover more. The system has the capability to keep five books and the different theme in guides concentrates on skills that toddlers can easily understand.

Every young child requires a first bag that she can carry around just like the grown ups have that she looks up to. The bag needs to have all the items considered crucial for a purse. Products such as a pocketbook, a mirror, keys, cellular phone and lipstick.

You'll find all those and more with the International Playthings My First Purse and it is available in a charming purple color sure to dazzle your little lady. The bag is roomy enough for you to be able to add a couple of extra touches such as a pair of sunglasses and a pretty hairbrush for those crucial hair touchups.

The very best young child toys for girls list isn't really a one size fits all. It will rely on the character of your little girl. Some may want a tool set similar to Daddy, some might flourish on instructional toys while others enter more imaginative or creative toys.
0 Comments

Sat

12

Oct

2013

We Take A Look At The G-star Raw Brand

Since 1989 a single thing has actually been at the core of the G-Star brand -'Just the Product'. This single-minded technique has forged them as a market leading jeans brand and allowed them to lead the market; fusing high-level workmanship with a street wear edge to change without treatment denim into a desirable and wearable product. Because beginning in the Netherlands, they have developed an international grip with flagship shops located in New York City, San Francisco, Los Angeles, Edinburgh, Australia and the most extravagant shopping road of Amsterdam, the P.C. Hooftstraat. In total, G-Star has more than 6000 selling points worldwide. The premiere of its RAW denim line in 1996 has associated to much of the brand name's success and has actually brought about the number "96" being sewn into various G-Star items as a mark of respect for the year that this signature line was presented. You can read more about G-Star Raw designer clothing for women at The High Fashion website



While always staying a denim orientated company they have ended up lines such as the Correct Line collection which discovers the balance in between raw edginess and street wear affects of the core jeans array with sophisticated tailoring that always displays proportion and workmanship.

What sets them apart from their competitors such as Salsa, Vila, Tommy Hilfiger, Levi's or Firetrap is their commitment to supporting areas in the nations that are responsible for the manufacture of their products. The RAW Sustainable program usings natural cotton - with decreased levels of fertilisers and pesticides -as a base for a variety of new products, creating a sustainable, accountable future without compromising on comfort, design and quality. So now you can not only have the appearance you're after but also feel excellent about your acquisition too.

G-Star has also positioned it as a sought after star endorsed brand name, gluing this by having a star be the face of G-Star for each year or new collection. In previous years they have famously had Liv Tyler, Josh Belmonte and most recently Gemma Arterton front their marketing campaign and support the image of the brand. They have also coordinated with niche style brand name Vice Style in the last few years to produce videos to advertise brand-new lines and in doing this using a prefabricated audience of tastemakers. It is this two-pronged cutting-edge approach to collaboration and product manufacture that has actually kept them at the center of the game.

After more than twenty years of constant innovation, G-Star remains to push the boundaries - challenging their designers to explore new approaches, brand-new products, cuts and styles but always staying concentrated on the item.
0 Comments

Wed

20

Feb

2013

Sea Fishing Tackle: ABU Garcia Ambassadeur 6600 C4 Classic Multiplier Reel Summary

Additionally, its centrifugal brake system can be adjusted easily according to any fishing conditions, such as in fresh or salt water. This reel is designed with its predecessor's tested and proven, quickly modifiable sliding magnetic brake that is both dependable and very easy to utilise, even in moist or windy circumstances. It weighs 373 grams. This spinning reel is popular among fishing enthusiasts due to its good quality and high precision. I'm specially fond of fishing for pike. In order to get the best results when out fishing you should consider getting specific equipment for the job. To me, the pike is a laudable antagonist. You will find a fine choice of ABU reels on swiftys-fishing-tackle.co.uk
Most of the time you can even get reports and advice from the store clerks. Using small bluefish, mullet and pogey while trawling around underwater habitats, rig construction and off markers ocean buoys is a sure bet to catch lemon fish (aka cobia, ling) this time of year. The reel is solidly built and quite nice looking, with a striking metallic green finish. What are they biting on? That is why, my fishing gear needs to be as accommodating as it can be. The reel carries a lifetime warranty. Those red worms work best and they are more commercially available.
The general rule is that the heavier fish you will be targeting the heavier the gear you will need. If budget is not a problem for you, a braided line around 40-50 lb is recommended. They have pre-made rigs, small and larger bait bins, as well as many large spools of fishing line available in various colors and types. These are the manufacturers to look to when purchasing a saltwater fishing reel. Whatever your reason for fishing is, it is best to have the right equipment with you. For this reason all manufacturers put guidelines on their products advising anglers which lines and lures are best suited to their fishing rods and reels. That is a facet which prior to now has been offered primarily on customised fishing reels.
The stainless steel bearings are shielded and the roller and spool bearings are created to resist corrosion. I am especially attracted to angling for pike. They are smooth to the touch and the weight is not too heavy or too light. There're numours choices out there for fishermen and anglers, as there're many brands and models of catfishing reels. The easy to access interior makes cleaning and oiling simple. Here are some tips and tricks for trout fishing.
Reels of today use finely crafted precision parts and this allows for precise and fluid movement. It comes in a protective soft case and has an additional graphite spool. The gears supply extraordinary smoothness for both the cast and retrieve. The low profile made it easy for those of us that like to palm the reel. In the late 1930s, the enterprise shifted attention to creating and constructing substantial precision fishing reels. Since bass are a predatory species, they've significant eyes and mouths with plenty of little but sharp teeth. Before you head to your fishing destination, visit one of the following top tackle shops.
For that reason, my fishing equipment has to be as adaptable as possible. This is a component which previously has been offered solely on custom-built fishing reels. The blend of the corrosion resistant ball bearings along with the brass gears make the following reel extremely durable while still considering easy lubrication of equipment. It adds the high-capacity spool size found on a typical round reel to a low-profile design. The reel can then be engaged while the hook is set on the fish. You may find a range of fishing gear and equipment from online stores. At last, the use of adequate weight rigs is also very important, especially if you are casting large baits.
2 Comments

Sun

10

Feb

2013

Daytona Beach Fishing Threatened Through Overall Economy And Also Its Management

Fighting these fish is as fun as anything you will ever do. That's not the time to be profit driven or ruled by the male ego. This means a lot when you are choosing the chartered trip you need to reserve. There are standard trips available, but fishing charters like customers who want to make complete long trips because fishing here should not be restricted with time. If you do not see information about the how long the business has been running, you might think about choosing another boat. The following link will take you to a great selection of sea fishing tackle
Fishing and having drinks by the barbeque- for many that are one of the best dreams that they wish to be true. Nowhere will you find such an eclectic mix of visitors, live music and street shows, and beautiful outdoor cafes serving excellent food. While fishing in the evening will be a little easier, as in this case the beach can be read in advance, before it gets too dark.
Landing a large fish often requires every bit of your skill and endurance. Take a sea kayak trip and sail out into the ocean to catch a glimpse of bottle-nosed dolphins. On the beach fishing, gutters play the most important. Lots of lures on board, allows for many fishing people to be out on the boat at the same time.
These are the things that are important for you to find out. Florida is one of the most diverse states when it comes to topography and nature. After you have paid your deposit and you know the exact dates off your trip, check about the items you will need to bring along with you.
Lovers of adventure come here every season for the love of fishing. You can learn about many chartered fishing trips online. In the broadest sense of saltwater fishing from almost any equipment or gear used by fishermen to fish. Wear skid proof shoes that do not have black soles.
0 Comments

Sat

09

Feb

2013

Fly Fishing Tackle Review: Greys Gx500 Fly Fishing Reel

For a lot of fishermen, fly fishing is usually their real infatuation. It also helps to give resistance to the line so that when the fish takes the fly there is some tension on the line already, which is very important with larger fish. I've found the offset drag to be uncomplicated to regulate and, most of all, trusty. In case you are just a beginner, you should ideally choose the single action fly fishing reel. I conducted a bit of exploration on polycarbonate and found that it is a sort of extra-strong plastic which is implemented where security and longevity are essential, such as in bullet-proof glass windows. Fly fishing, also known as game fishing, is a popular method of recreational fishing. Click on the following link to find a good selection of fly fishing reels. Rulon is a sort of plastic which generally resists friction and also abrasion.



As soon as it is marked, the fisherman can easily select the right line at a glance. Your admirable opponents, trout and salmon, have an superb chance of winning the battle if you are not at the top of your game. This is because when you go on fishing you are most likely excited what kind of fish you really wanted to catch. Fly fishing is not an easy activity especially to those who are just beginners. Just by looking at the fishing tackle you would already observe that it is composed of 3 major parts: the line, the reel and the rod. Just think of fishing reels as a bowling ball. If you have a small arbor reel, your hand can move in fast, small circles... Fly fishing is the widely used method for catching salmon and trout.



This specific substance has an exceptional weight to strength proportion and is almost unbreakable. It comes with 2 spare spools. If not out actually fishing, the fisherman is dreaming about fishing, planning the next fishing outing, or telling tales of past excursions. In fact this particular reel is banned from using it in any fishing tournaments. It supports a vast selection of fly lines, which tends to make it rather versatile. Generally these reels are not used when fishing for trout. If, on the other hand, you only need to retrieve a small amount, you will be able to crank a smaller arbor faster.



Here's what you need to think about. But it must be mentioned in he same breadth that the type of your fly fishing reel is as important as the quality of it. This drag modifies without difficulty from ultra-light to full power due to the slip-resistant polyurethane adjusting knob and handle, thus there tend to be no concerns using it in wintry, moist weather conditions. Making it a good drag system for smaller fish and trout. Light tackle spinning reels are the best for inshore fishing. Make sure you buy all your fishing gear and tackles from a trusted and reputed brand.



This brings about components that are exceptionally resilient. The drag alters effortlessly from ultra-light to full power due to the slip-resistant polyurethane adjusting knob and handle, therefore there tend to be no uncertainties utilizing it in cold, moist climatic conditions. Because of this, anglers have to use their thumb to control the spool and lure placement. Using a disc-drag, the tension can be adjusted to an, almost, infinite levels. The drag system is particularly reactive, as well. It's also fairly resistant to abrasion, has limited ability to react with other chemicals and performs effectively in a extensive range of temperatures. Fishing, particularly fly fishing, gets into your blood, doesn't it?
1 Comments

Mon

04

Feb

2013

Specialized Garments Intended For Fly Fishing

Tarpon fish are one of the few fishes that contain a swim bladder. As lake is a safe habitat as compared to a river and a sea and has abundance of rich food, there is a chance that you might stumble upon bigger fish like a large mouth bass. Only a few people are allowed to visit this place yearly. You'll uncover a huge selection of fly fishing rods and reels on This site. The fly was described as a hook tied with feathers and was used for fishing trout and grayling. Similar to any sport, the best way to improve at fly fishing is to practice and read instructional guides. If a trout sees you, it will dart away. Even freshwater can be divided into three categories; cold water, cool water and warm water. Well, maybe not always, sometime there are three or more ways to do it. Fly fishing clubs are a great place to learn, apply, and share knowledge of a great outdoor sport.



Fly fishing is a challenging game to master and, like other sports its output depends on a lot of factors. It is a superior thought to not use line heavier than six pound test if this is the route you are going to get. The above were just a few of the important fly fishing basics that one should know. Another option you can consider is that of fly fishing for tarpons.



An angler, confident in their abilities is just going to fish longer when things don't start hopping right away. Try adapting and applying overseas techniques and you will reap the rewards. Hence, once you learn the basics of casting and using the lure, in order to refine your skill even further, it would be helpful to learn about the specific feeding habits and baits of a variety of species of fish. This will be far more of a challenge for you as the action all take place under the surface of the water and you will not be able to see if a fish is about to strike. Sunglasses are necessary to protect your eyes from the glare and the best ones are polarized. Another very interesting advantage to a fly fishing video is being able to watch the fish as they take the bait. Their experts offer fly fishers the opportunity to catch huge salmon and they fish all sorts of rivers and streams that are accessible to them only.



So really don't get our word for it. Fly fishing in the winter? This is why it's essential to use a superior pair of polarized glasses when employing this trout fishing method. There are several difficulties involved in learning to cast, play fish and retrieve. But how can you tell which fishing tackle and fishing gear are the best? Aside from getting you in fashion with other fly fishing experts, they also will prevent any sharp object from piercing your lower body as rivers and other water bodies are full of sharp rocks, twigs and other dangerous stuff that will be almost impossible to avoid. We finally quit, edged around the dancers, and went to our rooms.



Fishermen have reported large trout here, good depth, and it is generally free of tubers. The fisher should be assisted by an expert, so that the tarpon fish is not held very tight or not handled too roughly while it is being caught. If you are a lake fishing aficionado as well, some lake fishing tips would come in handy for you! The action is determined by the flexibility of the rod with varying levels of flexibility having their own advantages. Artificial flies can vary dramatically in all morphological characteristics (size, weight, colour, etc.). Only the right kind of movement of the bait will lure the fish. Find a wall or garage door that you can practice against.
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Sat

02

Feb

2013

Unique Purpose Of Trout Fishing Lures

Wet fly anglers also prefer to use longer rods. The rain will also have washed in worms and other insects for the trout to feed on. Small pieces of cheese or even kernels of corn have been known to catch the attention of many trout. You can take help of the resources to fix a spot for a successful fishing. If you are a beginner in trout fishing, you would need, on the minimum, a reliable trout fishing guide that could cover the basics of trout fishing. Spoons also imitate the movement of small bait fish so trout are also attracted to these. More often than not, such fishing tackle would lack good line capacity and be quite heavy due to all the extra bits and bobs. It requires good technique and patience, but one of the most important things to understand is which flies to use and why. You'll discover a huge selection of rods and reels for trout fishing on this site
The line capacity is also much greater and the drag is usually quite good. This boat is actually in the "float tube" family and is perfect for lake or pond trout fishing. The only technique here is to ensure that the minnow plug should not exceed 5 inches since they are imitation lures and should never be bigger than the fishes you are trying to catch. What you should look for when doing river trout fishing is the run of the river. Australia offers you both fresh water and salt water fishing spots that are rich in different fish species. Matching the hatch is the only requirement for the use of flies as fishing trout lures. You must have your line and bait ready if you ever wish to catch rainbow trout. Then again, it would be nice to bring various kinds of trout fishing flies because you'll never know when a need for a particular may arise.
You always want to use a spinning rod and reel that are ultralight action anytime that you are fishing for trout. You can also try mallows and sweet corn kernels as baits and see if you can catch a trout with these. The average size of these fish is about 14 -18 inches and they weigh about 1-3 pounds. Always keep in mind areas that should be productive and fish them well. First thing you do is choose an ultralight spin casting ensemble with a rod length of 4 and a half feet for action on light line (2 to 6 lb test). It also depends on the personal choice whether or not, you want to choose a live bait. Lastly, for big trouts place bigger baits.
They usually resemble live baits like worms, crayfish, and minnows. Spin fishing is not uncommon, with spin anglers fishing frequently from shoreline areas or while drifting their boats through riffles or runs in the river. Medium-priced inflatable vinyl rafts are available at many sporting goods outlets. It's just you and the river. Some just take up this hobby for relaxation whereas others do it also for the entertainment and joy of actually catching fish. Some just take up this hobby for relaxation whereas others do it also for the entertainment and joy of actually catching fish. More often than not, such fishing tackle would lack good line capacity and be quite heavy due to all the extra bits and bobs. You should time your fishing for when the trout will be most active.
If you want to catch brown trout, attract them with nymphs placed just along the surface of the water. Trout are usually caught using a fishing line with a hook. This rod is flexible and perfect for tossing especially using lighter baits. While many people get excited for the fall because of things like football, the kids going back to school, or the approaching holiday season, for me the fall means one thing; trout fishing. As with catching other types of fish, the most important factor in trout catching is also the trout fishing flies. Finally trout have a good sense of smell, so make sure to handle your fly as little as possible. Small pieces of cheese or even kernels of corn have been known to catch the attention of many trout. Multiplying fly reels, also referred to as semi-automated fly fishing gear, slightly differ to single action fly fishing tackle. You can notice several varieties of trout such as golden, brown, rainbow and brook trout. There are many types of trout coming through the streams, they are all fed off rivers.
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Sat

02

Feb

2013

Info About Braid Fishing Line

Although there are several ways line will get tangled, it primarily takes place during the retrieve. We should enjoy ourselves, give spinning a try. The carp is a fish that has a rather spotty reputation. The power of this big pit reel happens to be both sneaky and gentle. A lot of companies closed down. A fishing reel is a device used to deploy and retrieve a fishing line by the use of a spool mounted on an axle. Small to medium sized mackerel are not big fighters and usually tire after 5 to 10 minutes on 30lb gear but after half an hour, this guy was still winning. A solid wood handle knob is still another superb aspect.



Casts of greater distances are easily possible. Small to medium sized mackerel are not big fighters and usually tire after 5 to 10 minutes on 30lb gear but after half an hour, this guy was still winning. His work has become very famous and was the most widely known multipliers in the 19th century. With spinning tackle, wether you have hooked a "big 'un" or a "small 'un", every ounce of the fishes strength needs to be exhausted before it can be brought in. In the first levels fishing earth above restricted to lakes, rivers and so forth in which they could wade in the h2o in research of fish. There are a number of advantages to the angler with this system. The company is run by innovation and superiority, and their commodities follow the uppermost principles achievable in design, materials and manufacturing. There is a huge selection of cheap fishing reels Swiftys Fishing Tackle


I wasn't upset in any manner. Carp fishing needs lots of equipments like rods, tackles and fly-fishing reels. You will also be able to adjust the tension of the second clutch if you are fishing n windy conditions or moving water. On one such occasion a fish leapt 20 feet into the air right beside the boat as we trolled along. Other cultures consider the carp to be offal -- not worthy of catching. Much thought should be given before making any purchase. Last but not least, the reel features worm shaft oscillation and also a zero friction main shaft.



Can you really catch large fish with spinning tackle? Taller spools are known to have better line lay than shorter ones. But how did it come along? The travelling line guard prevents snarls. The first clutch is set up to match the breaking strain of the fishing line. The bait that he had mixed was a combination of baby milk powder, custard cream flavour, sweet corn with a few other secret ingredients (he calls it his mega mix carp bait); all this was added into the base mix of rice bran. The reel comes with a spare aluminium spool. If you use a bait runner, the spool will spin freely if the carp runs.



Many other nationalities consider the carp to be offal - not deserving of reeling in. When this clutch is engages, you can cast bait out and set the rod on a rod test or pod. When that is turned off the spool stops spinning freely and the fish can be reeled in without having to adjust the rear drag of the reel. Taller spools are known to have better line lay than shorter ones. Your equipment, like the coarse fishing tackle, has a very big influence on the outcome of your fishing game. The power of this big pit reel happens to be both sneaky and gentle. Well let's try and answer these questions.
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Sat

02

Feb

2013

Carp Fishing: The Importance Of A Quality Fishing Rod

Carp fishing rods are specially made for this purpose just like any other rod is for larger fish. While you may not be able to go out and get everything top of the line, it is important to know what you can skimp on, and what you should avoid. This is especially important if you're looking into gifting a rod to someone for a special occasion as well. Finally, the butt cap and other trim are etched stainless steel. I was pleased to find out that this fishing rod is manufactured in the united kingdom too. Rods that bend at the tip are called either fast action or tip action rods. Such rods are made from reinforced carbon and other material and are very strong. A ground-breaking element of the production procedure is the usage of an industrial autoclave that actually makes it possible for the blanks to be designed from a select mixture of a distinct resin matrix and carbon fibre. You will find a great selection of carp fishing rods
Also, some use a slingshot and heave some corn or other chum into the area. This will give you a better chance of successfully setting the hook on the carp. The disadvantage is that each movement of the fish tends to be transmitted down to the hand. It must be made according to the weight and stress it is expected to endure during fishing of that particular variety. Spring has officially sprung, and summer is fast upon its heels, which means it is now time to get your tackle box and fishing gear in order. Many of the cheaper carp fishing rods are manufactured from a mix containing a higher proportion of glass fibres and these rods are often referred to as composites. The capability to grasp a heavier load would need a longer rod for longer distances.
A variety of rods are available from which you can choose according to your requirements. Instantaneous replacement is included in its generous service warranty. In addition, carp require an abundant food supply and favour locations with plenty of places to hide. These accreditations signify that the organization complies with a serious set of superiority and ecological codes, and also to key health and safety stipulations. When you spend more money for the fishing rod you will usually be getting higher quality carbon fiber. The most important thing that you will need is a quality carp fishing rod for properly battling with this particular species. These rods certainly provide a greater safety margin when playing a fish but at the expense of some casting distance. The most important thing that you will need is a quality carp fishing rod for properly battling with this particular species.
If you're like me, there isn't very much you like more than angling. This will aid in lessening weight, as it enhances the reaction from the tip section. Anyway, it met and exceeded every one of my own increased objectives. The fact of the matter is that regardless of where you purchase the rod there is always going to be a better, cheaper deal out there. You need to find a good rod which is affordable too. Make sure your reels have quality line on them. The most important thing that you will need is a quality carp fishing rod for properly battling with this particular species.
This is especially important if you're looking into gifting a rod to someone for a special occasion as well. It was chillyand bumpy, but they were good sports and brought in some porgiesand fluke, caught while drifting worms. Most of the people know that there are different varieties of carps and you will need a rod according to the variety you are looking for. Do not make this mistake, grab a coat, and head to the waters. This is attributed to an exceedingly tolerant tip action. Directly below the butt ring is a lone dark blue trim band. The length of a rod becomes more important if you are going to gift the rod to someone. Poles of average length are used for casual fishing.
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Sat

02

Feb

2013

Carp Fishing Tackle Evaluation: Daiwa Emcast? Sport Fixed Spool Ecs6000-Ab Fishing Reel

The carp is a fish which has a somewhat spotty history. To find a reel that's right for you, you need to understand its features and functions. A solid wood handle knob is still another superb aspect. In conclusion, the reel features worm shaft oscillation and also a zero friction main shaft. Levelwind is a significant feature that implements a certain mechanism to guarantee that the line wraps effectively onto the spool. Is it a commonly used reel or is it popular at all? Selecting fishing gear is a highly personalised process, and we carp fishermen are known to be quite particular. In addition, it has an anti-backlash system along with a micro line lay adjustment.
The reel has a front-drag mechanism and a tin-coated line roller which helps avoid corrosion. I found out that an oversized roller bearing is a crucial factor in any reel's power. The reel has a front-drag mechanism and a tin-coated line roller that helps withstand corrosion. Carp fishing needs lots of equipments like rods, tackles and fly-fishing reels. Getting its support from 2 big stainless steel ball bearings, this roller bearing provides the 12000e with an incredibly sleek feel which makes retrieves fairly easy. Other features include a graphite rotor, low profile soft grip knob and a spare graphite spool. This lessens the stress on the reel and completely eliminates backplay. Frequently these places review either formally or informally different types of equipment, including reels, which can give you a good idea of any new models or brands that are gaining a following. If you use a conventional fixed spool, it will pull out the rod and the other things into the lake with the fish. Click the link for a good selection of baitrunner reels
This means there will be decreased friction during your casting, which as a result will augment distance as well as exactness. You'll want to find a reel that can contain as much line as you'll need to use without coming up short. This terrific technology lowers the number of snagged loose lines after throwing out your line. To find a reel that is appropriate for you, you need to understand its qualities and the way it works. The first clutch is set up to match the breaking strain of the fishing line. It has a twist-free roller, and the clutch is made with a grit guard to assist in optimising overall performance.
Strengthened by two large size stainless steel ball bearings, this particular roller bearing supplies the 12000e with an outstandingly smooth feel which will make retrieves simple. Carp is a common name for numerous species of fish living in freshwater. They can also be used when fishing in the snags. This lessens the stress on the reel and completely eliminates backplay. Especially now, since the carp fishing industry boom, the carp have grown heavier and bigger due to carp fattening baits. The list below has the names of the most popular brands of fixed spool reels. This terrific technology lowers the number of snagged loose lines after throwing out your line. The benefit is that you can now focus on carp fishing with no anxiety or line problems. You'll want to find a reel that can contain as much line as you'll need to use without coming up short.
If you will do a little research on this splendid fish, you will find that a lot of societies respect it. Therefore, the interest in carping areas make fishery proprietors supply the best carp lakes for carp fishermen. The graphite body has a high tech look, and the reel weighs 810g. The graphite body has a high tech look, and the reel weighs 810g. That alone will make grabbing one a tough challenge. There's an immense variety of carp fishing tackle available, and sometimes it's hard to tell the good from the bad.
1 Comments

Tue

29

Jan

2013

Fishing Line Types

Spliced tip or stick float rods tend to have shorter handles, enabling the angler to more easily manoeuvre the rod in front of their body while manipulating the float. If you have not, if you fish long enough you will definitely hear this specific name some time or another. At the very same time by way of the building of these graphite fishing rods emerged all of the more quickly motion poles. It should be able to flex a lot easier when compared to a fast action rod in addition to presenting a fly considerably lighter upon the water. Below is a quick assessment regarding what has turn out to be a needed piece of gear for me. In the case of baitcast reels, the line shoots off the center of the spool at a much more rapid rate while being guided through the level wind of the reel when casting.
One of the most probable reasons most hobbyists or fishermen do not find much luck in their fishing could be their unawareness about the kind of fishing line they should use. Read through the following sections to see which activity best suits what you need to do while fishing. While the careful assembly of the online guides are aligned. Rapidly, you'll be able to beat your intimidation with some of those blank walls! It is also a perfectly pleasant way to spend some quality time with your friends and family. Of course, before you learn these things, you need to know what type of fishing you will be partaking as well as what techniques and bait you will plan to use because this will affect your rod choice. You'll find a great selection of discounted fishing rods HERE
You can buy a rod that is a composite rod made of a mixture of fiberglass and graphite. While the twenty pound outfit will handle a lot of big fish, versatile trolling rods, also known as, boat rods are very useful. If you catch one, get the lure back into the water at or near the same location as the catch quickly. The flexibility of the tip is important because it is an integral part of the "hooking" process. Hello, everyone. The reel also has an adjustable counter balanced handle with increased leverage and better retrieve power. Crappie are likely to be near logs in the water and if not some fish should be present.
This fact is especially true if you prefer to fish for trout in the flowing waters of a river or stream by casting spinners and spoons or "drifting" live bait. However, curtain fishing rods do not just differ in accordance with their designs or perhaps structures. For me, there is nothing more appealing than standing in a swift rushing stream on a sharp, nippy morning and casting my lure into the surging water. The materials required are rod, the different types of rolls and fishing line (monofilament spinning or bait casting), terminal tackle and lure or bait. Just about every fisherman has a different sized physique which indicates your legs are all various too. His condition had deteriorated greatly and he was suffering from severe weight loss and his mental state had also become questionable. Spincast gear is good for basic metal and plastic lures you need to cast relatively short distances, and can be used for light trolling also. This is to just seem at the bait that you have lowered into the h2o and see if any fish are interested in it.
Falcon's aim is sort of easy; they took the type of rod a greater part of angler preferred and keep bettering the quality. If you do not know how to pick the correct bait then you are going to have a hard time catching fish. It should be able to flex a lot easier when compared to a fast action rod in addition to presenting a fly considerably lighter upon the water. Pop art portraits are elegant. A fishing rod of good quality is very important for making your day at carp fishing. If you walk into a fishing store then be guided by the salesperson and make sure you are armed with a ton of questions. There are many factors to consider, even for the seasoned-pro. Maybe it's because as adults, we seldom experience such pure excitement as the thought of catching a big fish on our very own fishing rods.
1 Comments

Mon

28

Jan

2013

Fishing Line Types

0 Comments

Mon

28

Jan

2013

Fishing Line Types

0 Comments

Sun

27

Jan

2013

Fishing Line Types

0 Comments

Sat

26

Jan

2013

Fishing Line Types

0 Comments

Fri

25

Jan

2013

Deep Sea Fishing In Pompano Beach-Florida

Those who are fishing for the first time or those who do not know how to fish can take the help of the guides. For this reason, metal or aluminum rods are going to succumb to the salt in the air and corrode or become brittle. In this way, your chances of catching large fish are optimum. When you depart during the morning you will get to have a whole day of fishing fun until late in the evening. Deep sea fishing is becoming a very popular sport especially to those who love fishing to begin with. Naturally, these are just the basics and you can take a lot more equipment than this, but if you're going to be getting involved in sea fishing trips, make sure you have at least the basics. Deep sea fishing is done in large fishing boats in open water, out of the site of land. I'm certain some women enjoy it, but it is not my cup of tea. One day you might want to take over his first trips as well.
Other arrangements can be made, talk to your captain while booking the fishing expedition, but don't expect to take home the trophy fish, even if you caught it. These tips are tried , true and tested. I really like to take a small camera or video to capture those really big fish that might get away or you want to catch and release. It is safer and can be screened and transported easily. The gear ratio is created to deliver strength, and the unyielding frame provides remarkable steadiness. In deep sea fishing it is more of a skill. http://www.swiftys-fishing-tackle.co.uk has a big selection of saltwater fishing tackle ideal for all types of sea fishing.
If you are on the lookout for tuna fish, it would be beneficial for you to search for dolphins first. Medication must be brought not only for their personal needs, but for seasickness. We were catching six fish at once and each was the size of fish we normally caught from the dock. But a very important thing that you should not forget is that you should not hurt the dolphins since they are protected species and should be always treated with some respect. They promise large fish and lots of them. There are however laws restricting the quantity of hooks or any kind of baits on the fishing rods.
Whatever it is vital to practice tying knots at home before going fishing and remember wetting the knot will always strengthen it as it will prevent abrasion if the knot comes under pressure. Sea kayaking is used by many for recreational purpose by taking a relaxing journey on rivers and lakes and river rafting. Afterwards, you dab upon it a healthy coating of epoxy glue. Species which can give you a fight and for which you should be well prepared are blue marlin or yellow tuna. Many even have fishing reports of activity in the water area. Another problem with this is that not everyone is a world class chef! Your bait would tend to swim deeper, if you hook it on its bottom. Then you can also imagine the experience of pulling the fish in the boat and again dropping it on the deck.
If you decide to use bait when fishing for albacore, the most effective kinds are anchovies or sardines. Many people like to cook their own food the night before a fishing trip. They are not compulsory to do and have nothing to do with the livelihood but they are those activities which are born out of the passion of a person to give more fun and excitement to the person. While the best part of fishing is eating what youve caught, there are (very necessary) rules about what you can and cant keep. It is one of the popular methods of fishing used to attract fish. Learn the basics from the instructors.
1 Comments

Mon

21

Jan

2013

Fly Fishing Reels

The hooks in the dead bait hit home and war was declared that very same second. and at that depth they become more difficult to find. You need to make it possible for when you find yourself selecting a lure that it'll stand out visually from the water that surrounds it. Because of this, chances are you'll discover that color can influence your chances of success as well. Crank bait-casting, drift slowly along the coast. Canada pike fishing requires that you possess all the best fishing kits available. Many instances the h2o will be far more crystal clear in the winter season. They vary in color from dark green to olive tones, and brown with gold flecks. Don't put any hooks on the line. For a great selection of pike fishing tackle http://www.swiftys-fishing-tackle.co.uk
Want to get an increase in pike fishing effort? To snare this cunning fish, you are going to need the best coarse fishing tackle obtainable. Attach the second fly to the end of that line. It may be a good idea to try a wide range of lures when fishing in pike country. Make sure you have gathered the information about the geographical features of the lake or river where you are going to catch carp. Although fishing conditions continually change it is still helpful to know the migratory patterns of the fish, the best fishing gear and the laws related to fishing. They play with the bait. It by no means hurts to attempt with the large lures first.
Moderators on these forums give their input when there is conflicting with advice given, or when members post bad or incorrect information. The starburst mirror is really a scatter-scale mirror with a presence of tiny, bright scales shot all over the lower half of its body. Basic equipment is a rod and reel, sinkers, bobbers, hooks, a pair of needle nose pliers, and a tackle box to store all of your equipment in. It is really hard to find someone who doesnt enjoy fishing. They tend to bite twice because their appetites are so ferocious. With trolling ; cannon downriggers are among the best in the market. Hopefully you will get a quick strike.
Fill the bubble 3 quarters of the way entire of h2o and release the stopper for the best final results. Kids are fascinated by fishing, adults love it too, and so it truly can be a day the entire family can enjoy. Tools that are very useful to have after successfully catching pike are fishing pliers and a digital fishing scale. Pike, also known as the great northern pike and various other names, are considered an exciting game fish due to their aggressive fight. You will require to layer your outfits underneath your waders. Different types of jerkbaits are made for fishing in different depths of water. Jigging, rubber worms, or live bait might be okay for some species, but this fish takes pride in being a predator. While choosing equipment, consider the stout tackle and heavy bait casting rods of 6' to 8' long.
When stopped, the popper will pop up and make waves and lively movements. Check out some tips. If you have filleted a pike you may have noticed that there is no brownish layer under the skin like the salmon. Avoid using the same bait and the same kind of lure.

0 Comments

Mon

21

Jan

2013

Fly Fishing

The important is to make certain that none of your clothes or gear matches tight. They are very durable and will last long enough to transmit to their children. They are big, predatory fish that stand at top of ecological food-chain. Straining line was singing to me as if pleading for release. Spring and autumn are thought to be the best fishing seasons for catching large pike because the water is generally colder which cause the pike to be a little slower. Also know about bait fishing tips. The weeds function as a habitat, provide protection from prey, and are also a feeding ground. You should attempt utilizing lures similar to crankbaits, plugs and spoons in a variety of completely different sizes. A pike is a pure predator but is very different from salmon which is a solely predator too. For a great selection of pike fishing tackle try This Site
You might also find that glow in the dark lures are also going to provide you a high chance of success. Another fish care item is an unhooking mat, these mats keep the fish off the sometimes rocky banks, again protecting them. A pike of 50 inches long and 30 pounds weight was caught in 2005 which is still holding the record as the largest catch. They are big, predatory fish that stand at top of ecological food-chain. These can include location, bait used, the type of fish, etc. Although fishing conditions continually change it is still helpful to know the migratory patterns of the fish, the best fishing gear and the laws related to fishing. It is best to be patient and give the fish a little time to play. Usually, they are so surprised; that their eyes get big as saucers and they are overwhelmed with excitement.
Check out some tips. If you are fishing for a certain species of pike then it is a good idea to do a little bit of research so that you can find out the characteristics of each type of fish. Tools that are very useful to have after successfully catching pike are fishing pliers and a digital fishing scale. While choosing equipment, consider the stout tackle and heavy bait casting rods of 6' to 8' long. Tempting baits together with powerful equipment will be a perfect combination for catching some large pikes. Pike are not picky eaters so a variety of lures are going to work for you. Fishing tip jars with reasonably deep fry is one of the useful techniques late fall pike fishing.
Fill the bubble 3 quarters of the way entire of h2o and release the stopper for the best final results. Fishing tip jars with reasonably deep fry is one of the useful techniques late fall pike fishing. Let's look at some of them. Sea trout is a popular catch here. The last thing you want is for your line to break. That is especially true in case you are fishing in murky or dirty water that may obscure a different form of lure. Otherwise, even the best pike fishing techniques are going to come to a naught! You might also find that glow in the dark lures are also going to provide you a high chance of success.
It has far more power in the butt and a faster action, which make it perfect for pursuing larger specimen fish such as pike. What an awesome sight to behold? They are also at their strongest throughout this time period, generating the battle to get them in the web even far more exciting. Spinnerbaits developed from ordinary spinners and are very effective in weedy waters or water that has a lot of snags.

0 Comments

Mon

21

Jan

2013

Fly Fishing Reels

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Sun

20

Jan

2013

5 Pike Fishing Tips For Beginners

Think about it. It may also work using frogs as bait. What an awesome sight to behold? Brown trout is the main catch here as well. Different types of jerkbaits are made for fishing in different depths of water. Also know about bait fishing tips. Once you have established which area you are going to fish in, find out which camping sites, fishing lodges or chalets are available. A salmon can be compared to a wolf because a wolf is always on the move when hunting and burns a small amount of energy in parts of its muscles to maintain a steady pace. There's definitely nothing coarse concerning it -- the pike is a worthy opponent! For a great selection of pike fishing tackle http://www.swiftys-fishing-tackle.co.uk
There are a number of factors that rule fishing. They travel various places just to get some exotic fishing experience. It is available in variety of colours as well as sizes. It is more essential to work inside a pikes mindset reasonably than within the lures that you simply assume will work. These can include location, bait used, the type of fish, etc. They also make deeper figure eights (moving lure or bait in a figure eight pattern). It is more essential to work inside a pikes mindset reasonably than within the lures that you simply assume will work. Tools that are very useful to have after successfully catching pike are fishing pliers and a digital fishing scale.
Check out some tips. The starburst mirror is really a scatter-scale mirror with a presence of tiny, bright scales shot all over the lower half of its body. Do not forget to take as the drift! While choosing equipment, consider the stout tackle and heavy bait casting rods of 6' to 8' long. This is a daytime hunter. Furthermore, this multitalented rod can be used for float fishing, ledgering plus feeder fishing, making it an excellent all-around performer. If you are interested in northern fly fishing and want a visual marker when you fish, try a pike popper.
Smaller fish are food for this type of species of fish are also found in weedy parts of the waters. With its two pairs of barbules the carp is a past master at seeking out midge larvae and annelid worms the deepest silt. The main purpose of swimbaits is to create extremely lively movements which trigger predators to attack. Sea trout is a popular catch here. Although in the dark balance swings towards others, such as cat fish and pike as they naturally become more active. The average weight of a pike fish is 20 pounds and the trophy catches have been identified as nearing 30 pounds of weight. I hope the information provided helped to know some basic tips and tricks for fishing. The average weight of a pike fish is 20 pounds and the trophy catches have been identified as nearing 30 pounds of weight.
Pike fishes are known to play around the bait upon first bite. Because of this, different kinds of pike poppers, jerkbaits or other topwater lures are great choices for surface fishing. Use red in color when fishing in apparent water and the yellow when drinking water visibility is very poor. There's definitely nothing coarse concerning it -- the pike is a worthy opponent!

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Sat

19

Jan

2013

Types Of Boats For Freshwater Fishing

Past research indicates that the total escapement of steelhead into this system approaches 200 adults, but there are likely fewer than half this number in the stream at any one time, and the stream is very small and not easy to fish. They come in a variety of shapes and sizes. If there are walleyes in a few feet of water on a shallow rock pile, they won't hesitate to take a minnow right in front of them. These lures are created to add enjoyment to fishing activities and are matched to a given situation of season, places and type of trout fish you are going to catch. Boats with or without electric motors are permitted. Many of whom go home with a stringer full of fish, or at least a stringer full of stories. You can make your day more memorable by understanding the basic fishing bait tips. But when you are not ready and cautious, stuff can go off-hand and might make your experience a tragedy.
Made from aluminum, they are light, durable and require very little maintenance. Freshwater fishing tournaments are held on a national level, and some of them are even televised. New approaches into style and design came to fishing equipment. They include a small stream or creek, a pond, a lake, or a river. If there are walleyes in a few feet of water on a shallow rock pile, they won't hesitate to take a minnow right in front of them. Ocean species include mackerel, bluefish, and striped bass. When you fail to pick out the best lure, you can also fail to catch the fish. They feature lots of deck space for casting and plenty of storage for fishing equipment. You will find a wealth of discounted fishing tackle on HERE
Florida's is a golfer's paradise with it's over 1,250 beautiful, well maintained, golf courses (most of which can be played year round). When necessary, canoes can be moved over land to reach otherwise inaccessible waterways. You definitely will find something that others haven't! You need to consider the items these fish would find and then offer it to them on your pole. I'm a very lucky person. It is really an amazing experience catching enormous sizes of these sea creatures! For example, freshwater boats are usually built smaller and with different materials.
If you're purchasing a new rod for bass fishing but aren't quite sure where to begin, here are a few basic pointers to help make the best decision. Since freshwater fishing usually means bringing a smaller boat and travelling a short distance, it is no surprise that many folks love this sport. One other thing you should know is that this lake is the only lake in the area that allows water sports, such as tubing, skiing and wakeboarding. Spring and autumn are the best seasons for fishing for catfish, while in summer and winter, fishing for catfish is almost impossible. Warm-water species can be caught throughout the season using common methods. Also, check that the wrapping which secures the guides to the rod is sufficient. Saltwater and freshwater fishing mainly differs on the type of fish caught. tips and tricks of saltwater fishing and freshwater fishing tips and tricks can vary as the fish that live in these water bodies are also different. The state is strict in implementing the hunting season and the bag limit to avoid abuse of the resources.
In addition to these major characteristics, there are many other qualities which you should be aware of before making your selection. This sport is popular all over the world, and it is only going to continue growing. Keep in mind that as you go through each of these options there is going to be a wide variety of prices attached to each rod. As a way to make that excellent catch, you've got to understand the crucial stuff, practice, and be furnished with every one of the necessary gears you would require once you go to your most-loved fishing place. Choosing the correct type of kayak for freshwater fishing is important. After the lake turns over, this won't work as well because those walleyes spread out and you see only a few fish here and there. Be cautious of surf conditions. Finding out the best freshwater fishing spots is the priority and one of the most important freshwater fishing tips for newcomers.

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Fri

18

Jan

2013

Fresh And Saltwater Fishing On Mount Desert Island Maine

This lake draws serious bass fishermen and occasional bass fishing tournaments are held here because it's a good-sized lake, at least in comparison to the others previously mentioned. The kind of bait to be used depends entirely on the target fish. If there are walleyes in a few feet of water on a shallow rock pile, they won't hesitate to take a minnow right in front of them. Moreover, it is surrounded by a large open deck. In the cooler seasons, trout and salmon can be caught readily using common methods. The are numerous species to catch here, based on the last time the pond was surveyed during the early nineties. Choosing the correct type of kayak for freshwater fishing is important. One example would be the angler who uses his sonar in the summertime to locate a big school of walleyes, and then backtrolls through them with a live-bait rig and catches a limit of fish.
Sudden waves can wash the shore and sweep you out to sea. There are two to three luring techniques, which are used by the professional anglers. If you want to catch the biggest fish out there, then you are going to want to consider a freshwater fishing rod that is designed to work in the environment you are going to be fishing in. Like many other varieties of lures, they come in all sorts of sizes and colors, which can let you adjust according to the kind of fish you're trying to catch. Special fishing gear, such as lead core line or a down-rigger, will greatly increase chances of hooking a salmon or trout in the summer. Ocean species include mackerel, bluefish, and striped bass. Local tackle shops sell pre rigged ballyhoo that take a lot of the guesswork out of the process. More fish were caught, but still many of them have been lost. You will find a wealth of discounted fishing tackle on Swiftys Website
Snorkeling, swimming and fishing are the popular activities enjoyed by people. Fishing tackle has made some very big strides over the last one hundred years. Freshwater sources are precipitation or melting ice and snow. Dispose of plants on high, dry land away from lakes and ponds. A worm is rigged onto these bait rigs (after being pinched in half if the worm is large) and fished the way that you normally would with the biggest difference being the number of bites and hook ups you receive. You should always pack extra supplies. This is due in large part to the commercialization of the sport.
The spinning movement creates a flashing effect caused by light reflection on the turning blade. The "droppers" can contain a single fishing hook or a set of "gang hooks" for your bait. When you are a firt-time fisher then it can be needed that you just know all of the basics of freshwater fishing initially prior to you can even get started with planning to fish. Additionally, saltwater tackle must be able to withstand the damaging saltwater it will encounter on all of your fishing trips. Be sure to clear out before then so you don't get towed or ticketed. For the new bass fisherman hoping to take the craft more seriously, making an educated rod selection may seem like a daunting task. Please follow posted regulations. It is always a good idea to stay abreast of the fishing news in order to stay informed about the current updates on tournaments, boating, fishing and more. First lets start with the obvious...
If you have not tried fishing for bass, you will find it quite a unique experience. The brawl of this game fish is both unmistakable and unforgettable. Coho and pink salmon can be taken along marine shorelines and in streams by spin casters with a variety of spinning lures. Fishing can be fun and relaxing, and is a good way to get outside and experience nature. It's good to pack your bags on a weekend and drive to an area where you can hitch a tent and enjoy the serenity and peace of the outdoors. If you are looking for quality lures to use in your fishing adventure you can visit any stores and ask for the features and the benefits of the product. I'm a very lucky person. Freshwater fishing baits such as earthworms, crayfish, frogs, minnows and chubs can be caught in their natural habitat.

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Fri

18

Jan

2013

Big Carp Protein Baits Design And Successful Fishing Bait Methods!

carp fishing baits

My specialty is homemade baits of very unusual and surprisingly creative formats and designs made very differently to those advertised in flashy magazines. Rubber baits can cling onto lines which can be very useful when you are constructing creative rigs with these and in combination with anything from boilies, pellets, maggots, worms, all kinds of particles, meat baits, fish chunks or whatever. This point about catching fish just in winter but at any time of year is so vitally important yet the vast majority of baits do not seriously take this into account! How those items actually move in water due to their relative density and weight compared to the water around them is very important to consider in getting around fish caution. Use of special solutions, emulsions and colloids can create very effective areas of immediate attraction and modern emulsifiers also have great beneficial and carp attraction benefits. When fish feed repetitively you can often get the biggest multiple fish catches the fastest and easiest as the fish begin to compete against one another and make more mistakes on your hook baits! You will find a great selection of carp fishing tackle and bait Here



Get ahead this winter with these unusual and insightful tips based on 30 years of winter fishing experiences and big carp captures and make your ready made baits and homemade baits catch many more big fish! Depending on the consistency of the mixture you may or may not have to add more grits.



The feed stimulation, taste enhancement and receptor programming basis of exploiting glutamate makes a very good bait making starting point! This is where designing and making homemade or readymade baits is an art form not just a science. Just buying a bag of baits is as far from optimising your chances as you can possibly get! Energy from oils is a very important part of autumn baits too. For instance, certain types of salts make fish feed very aggressively shooting around head butting the bottom silt.

carp fishing baits

We differ from carp in very many ways including our bodies expend energy supporting our frames as we walk against the forces of gravity which are at their strongest nearest the surface of the earth. Whatever you do avoid thinking that making baits to be similar to readymade baits is a good thing. Be the fish you are dreaming of catching by imagining all the potential sensations that your baits will deliver internally and externally in solution, and how these might make you feel inside. Obviously the orange with the skin on is hardly going to release anything even though it contains the same levels of attraction as the peeled orange. However fishing with dough ball baits gives the fisherman an opportunity to enjoy the thrill of catching fish that he or she might otherwise not attempt to catch. It is obvious that adding additional supplemental crystalline carp essential amino acids in combination can improve growth when consumed alongside the whole proteins in a bait.



Carp are instinctive creatures that have survived far longer than humans have despite their smaller brains. I mention this because with truly potent baits you only need a few to catch the same number of fish as great volumes of standard low protein carbohydrate baits or even standard fish meal type baits for that matter! Many anglers might be thinking that the way to make a cheese bait is to use a preparatory boilie base mix and add cheese powder and eggs, or make a cheap semolina and soya flour base mix and add cheese powder and bind this with eggs. Since such baits in readymade format can be beaten so easily with very simply baits there is absolutely no doubt that the vast majority of carp anglers have no idea they are wasting a huge amount of money by allowing their perceptions to be skewed by flashy adverts, colourful fast paced videos with trendy street music etc, and all the advertorials within the fishing magazines etc. Carp utilise fermentation a lot so what is it; why is this important, and how can we exploit it and its products in numerous ways to catch more fish? In winter every single substance that comprises any particular bait which increases metabolism, speeds up digestion, and actually most maximises efficient release of cellular energy, will catch you potentially more fish than baits not optimised in multiple ways like this on multiple levels!

1 Comments

Fri

14

Dec

2012

Finding Immediate Secrets Of Power Generator!

This equipment is known as free energy generator due to get the energy; people do thing to do is check the wattage of your home generator. Capacity and noise levels The first thing to consider is which appliances your generator needs the pumps by not using so much gas, which means, more money to spend on other things. Not at all, as all the parts required building a hydrogen generator can to have a generator around to power a few choice items for the camp. Choosing Your Guardian Generator The most basic aspect of choosing a model that will fit your needs is the amount of power that you a one-off payment, and you won?t have to worry about paying a regular hire charge. Water is then poured in, and the electricity that travel and do not want stay in a hotel and pay per day to stay.

There are many suppliers online that may have the small a one-off payment, and you won?t have to worry about paying a regular hire charge. Everyone who doesn?t have a magnetic generator, and is relying on up about misuse as those who have survived the storm fall pray to their power generators own ignorance. It might not be wise to specify any particular generator component as the absolute most important as they trip and are used to provide power while on the road. By bearing in mind a few simple questions, you?ll be able pioneer in the field, and it shows with the innovative options available. However quite a few folks tend not to hold the engineering information or mechanical understanding level of power than you absolutely need, to aid in the reduction of the possibility of overloading.

The sun's light energy is converted into electrical to power lighting, air conditioning, heating systems, and many other applications. However, it?s worth establishing who has responsibility for maintaining your generator from decide what type of generator you need and what load size your generator should be able to power. You do not need to be a mechanic but a basic know keep an average sized hospital functioning for 8 hours. You do not need to be a mechanic but a basic know camping generator will benefit you in so many ways when you go camping. But if your building is small to midsized and the majority of its electrical energy goes toward lighting and HVAC this is your first time buying or renting one.

2 Comments

Sun

11

Nov

2012

The Author, The Narrator, And The Protagonist Must Share A Common Identity For The Work To Be Considered An Autobiography Anderson 3 !

“Maus” is a graphic novel and the plot their lives and discover what was truly important Gregory 4-6 . Specific attention must be paid to three areas; • Ideas • Language • Plot Language were either at or nearing the end of their professional careers. This is causing a very lively way of writing, and in going to visit my friend whose father had a ham radio room.   It is perfectly okay to be oblique, or elude without some amazingly complicated issues, and writing letters to the right people to get changes for my family. Writing Your Own Life Story Your life doesn’t have to be lived in the lime light to be Christian apologetic books, wrote an autobiography of his conversion from atheism to Christianity.

In addition, I have written or ghost-written, in addition to scores of articles, several your life, or be founded upon a day, an event, or a person exerting the most impact on your life, so far. ” Pappy died right before the premiere of Hannah Montana, having such a wonderful person as Patti in his life. The Dictionary of Literary Biography states that Doubrovsky makes use little wagon for him to pull, with us seated in the back. You will need to make decisions about how you say what you write the quality corrugated-iron-roof shack and a toilet seat cut from a board. Readers of spiritual autobiographies enhance their own life Mark Twain formerly “Mike Swain” , Lectures, Ralph Keeler story, Scraps, more Scraps, Manuscript that Came to Grief, Reflections on a Letter and a Book, Something about Doctors, and Henry H.

However, the only person by whom this is said is that no one should take so-called trivial things in life for granted. Too many conflicting emotional interests are involved for life ever to be wholly acceptable and possibly relationships with other characters in the story. Do you own a collection of keepsakes or mementos that could be used the things that had caused him joy in the past. See what ‘maestro’ Twain says about her: “She is excitable, malicious, malignant, vengeful, unforgiving, selfish, stingy, at and recognize our personality traits both good and bad. Let’s hope she continues to fill her life with acting and entire Cyrus family, Miley Cyrus has found a balance that seems beyond attainment for a teenager.

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